Protein Alignment CG16965 and PGGHG

DIOPT Version :10

• Sequence 1: NP_609528.3
• Gene: CG16965 / 34607
• FlyBaseID: FBgn0032387
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_079368.3
• Gene: PGGHG / 80162
• HGNCID: 26210
• Length: 737
• Species: Homo sapiens
• Alignment Length: 695
• Identity: 221/695 - (31%)
• Similarity: 340/695 - (48%)
• Gaps: 58/695 - (8%)

  Fly    20 ETPETYLLKTHSLPSDLNFMPTLGNGHVGYTIFGDAIFMNGVYNGAGGNSKRARIPNWINISTEA 84
            |.|.|:  ..||||||...:.|:.|.::|..:|.|.:.::||||||||::.||.:|:.:|:..||
Human     6 EDPTTF--AAHSLPSDPRLLATVTNAYLGTRVFHDTLHVSGVYNGAGGDTHRAMLPSPLNVRLEA 68

  Fly    85 CDRFGCATDSDVVNGTSYEMNLRDGYFRVVTTYRGLGISVEQRTYPHKYYNRALVYEVVANRLAG 149
            ....|     :.:..| :.::...|.|  :.|..|......|..|.|:.....|.:.|...|||.
Human    69 PAGMG-----EQLTET-FALDTNTGSF--LHTLEGPRFRASQCIYAHRTLPHVLAFRVSIARLAP 125

  Fly   150 RNSRINSPKFLRLTQFAGNFSDAFDFVVVNNGSSASGNYRTLRGQTKVVENEQFQP--DPQEIFV 212
            .:..|.   .|..:.|:....|    :.::.|....| .|.|.|.|...|    ||  ..||:.:
Human   126 GSGPIT---LLLRSAFSPESPD----LDLHQGPDFQG-ARYLYGHTLTPE----QPGGPQQEVHM 178

  Fly   213 LFSESLEQPLELQWPTWQDQLSHRVIIAIDRDESVTRKELQDVLQLSSDN-LLQKHSQSWNSFWD 276
            |::.:   |.:|.....::..:...:.|:...::..:..|.:.|||.:.. |...|:|:|...|
Human   179 LWTPA---PPDLTLGEGEEARTWDFLTAVGGSQAEAQACLTEALQLQARGALYTAHAQAWAQLW- 239

  Fly   277 DEFSIEIKGDALELSQIVNAGIFYIVSSLPSLETNQKNELFYGLSPTGLGRGNLEADYQGHNFWD 341
            .|..:::.| .|:|.|.:...::|::|:||  :......:.:||||.||..|:.|..|.||.|||
Human   240 VECGLDVVG-PLQLRQALRGSLYYLLSALP--QPKAPGYICHGLSPGGLSNGSREECYWGHVFWD 301

  Fly   342 TEIWMLPIVSLFGLDYAKEVLGYRSRKLEAAKYHANATGYKGARFPWESAYTGTEVTNPCCPE-- 404
            .::||.|.:.:|..:.|:.:|.||.|.|:.|..:|...||:||:|.||||.:|.||    |||
Human   302 QDLWMFPSILMFHPEAARAILEYRIRTLDGALENAQNLGYQGAKFAWESADSGLEV----CPEDI 362

  Fly   405 VAEQEIHISPDISFALQKFFAQSNDSE-WTCGTAWPITADVADFLVSRATCDDSTKTCHLLNVMG 468
            ...||:|::..:..|.:.::..:.|.: :.....|.:...||:|..||.......:..||..||.
Human   363 YGVQEVHVNGAVVLAFELYYHTTQDLQLFREAGGWDVVRAVAEFWCSRVEWSPREEKYHLRGVMS 427

  Fly   469 PDEDHPNVNDNVYTNAVSKIALNFAEWLAKHCGNASTERLEKWREVSDGLVILRDESLNYHPEYA 533
            |||.|..||::||||.:.:.:|.||..||:..|....   .:|..|:|.:.:..|...|:|||:.
Human   428 PDEYHSGVNNSVYTNVLVQNSLRFAAALAQDLGLPIP---SQWLAVADKIKVPFDVEQNFHPEFD 489

  Fly   534 GYVRDTIIKQADTILLGYPLNFDKS-STHINDLRFYANVTRESGPAMTWSMFAANYLRNLQLTLA 597
            ||....::||||.:|||||:.|..| .....:|..|..||...||||||||||..::.......|
Human   490 GYEPGEVVKQADVVLLGYPVPFSLSPDVRRKNLEIYEAVTSPQGPAMTWSMFAVGWMELKDAVRA 554

  Fly   598 NEYFERGYKSYVRPEFKVWSETPIGYDGSANFLTGIGGFLQALIFGYGGLDFGRTDDDQFLMFFG 662
            ....:|.:.:...| ||||:|...| .|:.|||||:||||||::||..|....|.         |
Human   555 RGLLDRSFANMAEP-FKVWTENADG-SGAVNFLTGMGGFLQAVVFGCTGFRVTRA---------G 608

  Fly   663 ISLTP---PNVEEVFINSIPYGQHAKCTLRFKSRHSEISCYDRIG 704
            ::..|   ..:..|.::.|.| |..|....|......:....|.|
Human   609 VTFDPVCLSGISRVSVSGIFY-QGNKLNFSFSEDSVTVEVTARAG 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16965	NP_609528.3	ATH1	41..>551	CDD:441163	158/515 (31%)
PGGHG	NP_079368.3	ATH1	<211..649	CDD:441163	158/460 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	681..737