DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Or33a and Or23a

DIOPT Version :9

Sequence 1:	NP_523553.1	Gene:	Or33a / 34601	FlyBaseID:	FBgn0026392	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_523458.3	Gene:	Or23a / 33450	FlyBaseID:	FBgn0026395	Length:	379	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	113/376 - (30%)
Similarity:	194/376 - (51%)	Gaps:	21/376 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SENLYKTYWLY----WRLLGV----EGDYPFRRLVDFTITSFITILFPVHLIL-GMYK-KPQIQV 63
            ||.|...|:..    ||:.|.    ||.|     ..:::...|.:..|..::| |:|. :..::.
  Fly     4 SETLKIDYFRVQLNAWRICGALDLSEGRY-----WSWSMLLCILVYLPTPMLLRGVYSFEDPVEN 63

  Fly    64 FRSLHFTSECLFCSYKFFCFRWKLKEIKTIEGLLQDLDSRV--ESEEERNYFNQNPSRVARMLSK 126
            ..||..|...|....||..:..:|.::..::.|:..||:||  ||:.||   ::|.:.....:||
  Fly    64 NFSLSLTVTSLSNLMKFCMYVAQLTKMVEVQSLIGQLDARVSGESQSER---HRNMTEHLLRMSK 125

  Fly   127 SYLVAAISAIITATVAGLFSTGRNLMYLGWFPYDFQATAAIYWISFSYQAIGSSLLILENLANDS 191
            .:.:......|.|.|..:|.|..:|....|||:|::.:...|..:..:|.||....|::..|.||
  Fly   126 LFQITYAVVFIIAAVPFVFETELSLPMPMWFPFDWKNSMVAYIGALVFQEIGYVFQIMQCFAADS 190

  Fly   192 YPPITFCVVSGHVRLLIMRLSRIGHDVKLSSSENTRKLIEGIQDHRKLMKIIRLLRSTLHLSQLG 256
            :||:...::|...:|||:|:|.||:..| :..||.:.|:..|:|...|.:::.:.:|.:....:.
  Fly   191 FPPLVLYLISEQCQLLILRISEIGYGYK-TLEENEQDLVNCIRDQNALYRLLDVTKSLVSYPMMV 254

  Fly   257 QFLSSGINISITLINILFFAENNFAMLYYAVFFAAMLIELFPSCYYGILMTMEFDKLPYAIFSSN 321
            ||:..||||:|||..::|:.|..:..:||..|...:.::.:|.||||.::...|.:|.||:|.||
  Fly   255 QFMVIGINIAITLFVLIFYVETLYDRIYYLCFLLGITVQTYPLCYYGTMVQESFAELHYAVFCSN 319

  Fly   322 WLKMDKRYNRSLIILMQLTLVPVNIKAGGIVGIDMSAFFATVRMAYSFYTL 372
            |:.....|...::||.:.|.....:.||.:|.|.:|.:.|..:.||||:||
  Fly   320 WVDQSASYRGHMLILAERTKRMQLLLAGNLVPIHLSTYVACWKGAYSFFTL 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Or33a	NP_523553.1	7tm_6	61..367	CDD:251636	92/307 (30%)
Or23a	NP_523458.3	7tm_6	59..365	CDD:251636	92/309 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468590
Domainoid	1	1.000	80	1.000	Domainoid score	I15406
eggNOG	1	0.900	-	-		E1_29KC3
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I7421
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326193at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm50671
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21137
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900