Protein Alignment Mal-B2 and MAL12

DIOPT Version :9

• Sequence 1: NP_001188791.2
• Gene: Mal-B2 / 34598
• FlyBaseID: FBgn0032382
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_011808.3
• Gene: MAL12 / 853209
• SGDID: S000003524
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 568
• Identity: 178/568 - (31%)
• Similarity: 260/568 - (45%)
• Gaps: 104/568 - (18%)

  Fly    34 WWPHTVFYQIYPRSFKDSNGDGIGDLKGITSKLRYLADTGITATWLSPIFQSPMIDFGYDISDYK 98
            ||.....|||||.||||||.||.||||||||||:|:.|.|:.|.|:.|.:.||..|.|||||:|:
Yeast    13 WWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYE 77

  Fly    99 AIQPEYGTMQDFEELIDTAFELGIKVVLDFVPNHSSDQHEWFKKS-AAREPGYEDFYVW-----H 157
            .:.|.|||.:|..||||...:||:|.:.|.|.||.|.:|||||:| :::.....|::.|     :
Yeast    78 KVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGY 142

  Fly   158 DGIVQENGTRVPPNNWPSVFYGSAWEWHEGREQYYLHQFTKEQPDLNYRNPKVVQAM-DDVLLFW 221
            |.    .|..:|||||.|.|.||||.:.|...::||..|...|.|||:.|....:|: :..:.||
Yeast   143 DA----EGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFW 203

  Fly   222 LNKGVAGFRIDAVNHLFEDESLKDEPLSGKTTDSLSYDYTKHIYSRDLPEVLEMIHHWRQLLDDF 286
            |:.||.|||||......:...|.|.|:..||:.....::..|...|        ||.:.|.|..|
Yeast   204 LDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPR--------IHEYHQELHRF 260

  Fly   287 SAKHPERPTRIMMTEAYA-----GLTQLADYYEDSNGVRGSH-------------LPF------- 326
            .....:....||.....|     .|...|..||.|.....:|             :||
Yeast   261 MKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQWKE 325

  Fly   327 ----NFHFITDVKGDSDARDYVYNVEKWLIYMPRGHAANWVMGNHDNPRVASRFG-------PAS 380
                ||.||...  ||.|..|:                    .|||..|..:||.       ..|
Yeast   326 AIASNFLFINGT--DSWATTYI--------------------ENHDQARSITRFADDSPKYRKIS 368

  Fly   381 VDAMNMLLLTLPGVAVTYNGEELGMVDYRELSWEETVDPPARNVGEKLYQE-------------- 431
            ...:.:|..:|.|....|.|:|:|.::::|...|:..|...:|..|.:.:.
Yeast   369 GKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKG 433

  Fly   432 ---VSRDPVRTPFQW-NNETNAGFS-TAAKTWLPVHPNYLE-LNLEAQKVANRSHYQVYKDLLEL 490
               :|||..|||..| .::.||||: ...|.|..::.::.: :|:|.:...:.|....:|..|:.
Yeast   434 IALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQA 498

  Fly   491 RK--SAIMRVG---RFNIEPLTRWVFAFKRSYPNFESIITVINVSDKE 533
            ||  ..:|..|   :| |:..:..:|:|.:.|.: :::...:|.|.:|
Yeast   499 RKKYKELMIYGYDFQF-IDLDSDQIFSFTKEYED-KTLFAALNFSGEE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-B2	NP_001188791.2	AmyAc_maltase	33..502	CDD:200467	170/535 (32%)
		Malt_amylase_C	510..>541	CDD:351862	6/24 (25%)
MAL12	NP_011808.3	AmyAc_SI_OligoGlu_DGase	15..501	CDD:200472	165/519 (32%)
		Malt_amylase_C	511..583	CDD:406946	8/36 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342191
Domainoid	1	1.000	192	1.000	Domainoid score	I624
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	257	1.000	Inparanoid score	I641
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000282
OrthoInspector	1	1.000	-	-		mtm9159
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10357
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R680
SonicParanoid	1	1.000	-	-		X202
TreeFam	0	0.000	Not matched by this tool.
	11	10.920