DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mal-B2 and amy2al1

DIOPT Version :9

Sequence 1:	NP_001188791.2	Gene:	Mal-B2 / 34598	FlyBaseID:	FBgn0032382	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_956722.1	Gene:	amy2al1 / 393400	ZFINID:	ZDB-GENE-040426-1606	Length:	512	Species:	Danio rerio

Alignment Length:	553	Identity:	108/553 - (19%)
Similarity:	176/553 - (31%)	Gaps:	236/553 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 RYLADTGITATWLSPIFQSPMI------------DFGYDISDYKAIQPEYGTMQDFEELIDTAFE 119
            ||||..|.....:||..:|.::            ...|::..      ..||.::.:::|.....
Zfish    45 RYLAPNGYGGVQISPPSESIVLTKPWHPWWQRYQPISYNLCS------RSGTEEELKDMIARCNN 103

  Fly   120 LGIKVVLDFVPNHSSDQHEWFKKSAAREPGYEDFYVWHDGIVQENGTRVPPNN--WPSVFYGSAW 182
            :|:.:..|.|.||          ......|        :|.....||.....|  :|||.| |:|
Zfish   104 VGVNIYADAVINH----------MCGASGG--------EGTHSSCGTYFNAKNEDFPSVPY-SSW 149

  Fly   183 EWHEGREQYYLHQFTKEQPDLNY------RNPKVVQAMDDVL---------LFWLNK----GVAG 228
            ::::.:.:      |..:...||      |:.::|..:|..|         ..::||    ||||
Zfish   150 DFNDNKCK------TANEDIENYSDIFQVRDCRLVSLLDLALEKDYVRGKVAEYMNKLIDIGVAG 208

  Fly   229 FRIDAVNHLFEDESLKDEPLSGKTTDSLSYDYTKHIYSRDLPEVLEMIHH-WRQLLDDFSAKHPE 292
            ||:||..|::..:                   ..::|||     |:.::: |      ||.
Zfish   209 FRVDACKHMWPGD-------------------LSNVYSR-----LKTLNNTW------FSP---- 239

  Fly   293 RPTRIMMTEAYAGLTQLADYYEDSNGVRGSHLPFNFHFITDVKGDS-DARDYV---------YN- 346
                                     |.:    ||.:..:.|:.|:. .|.:||         |:
Zfish   240 -------------------------GTK----PFIYQEVIDLGGEPIKASEYVSLGRVTEFKYSA 275

  Fly   347 -----VEKW----LIYMPRGHAANWVMG--------------NHDNPRVASRFGPASV----DAM 384
                 :.||    |.|:     .||..|              ||||.| ....|.|||    |:.
Zfish   276 KLGTVIRKWEKEKLCYL-----KNWGEGWGFMPSDKALVFVDNHDNQR-GHGAGGASVLTFWDSR 334

  Fly   385 NMLLLTLPGVAVTYNGEELGMVDYRELSWE----------ETVDPPARNVGEKLYQEVSRDPVRT 439
            ...:.|...:|..| |....|..||   |:          :.:.||:...|......::.|
Zfish   335 LYKIATGLMLAHPY-GVTAVMSSYR---WDRHFVNGKDQNDWMGPPSNADGSTKSVPINPD---- 391

  Fly   440 PFQWNNETNAGFSTAAKTWLPVHPNYLELNLEAQKVANRSHYQVYKDLLELRKSAIMRVGRFNIE 504
                        ||....|:..|                 .::..::::..|...       |.:
Zfish   392 ------------STCGDNWICEH-----------------RWRQIRNMVNFRNVV-------NGQ 420

  Fly   505 PLTRW------VFAFKRSYPNFESIITVINVSD 531
            ||:.|      ..||.|....|    .|||.:|
Zfish   421 PLSNWWDNNNNQIAFSRGSKGF----IVINNND 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mal-B2	NP_001188791.2	AmyAc_maltase	33..502	CDD:200467	96/516 (19%)
Mal-B2	NP_001188791.2	Malt_amylase_C	510..>541	CDD:351862	8/22 (36%)
amy2al1	NP_956722.1	AmyAc_bac_euk_AmyA	25..417	CDD:200456	96/508 (19%)
		AmyA	46..>315	CDD:223443	69/367 (19%)
		Aamy_C	424..511	CDD:214749	9/30 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740