DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Mal-B2 and AGBE

DIOPT Version :9

Sequence 1:NP_001188791.2 Gene:Mal-B2 / 34598 FlyBaseID:FBgn0032382 Length:583 Species:Drosophila melanogaster
Sequence 2:NP_788342.1 Gene:AGBE / 326264 FlyBaseID:FBgn0053138 Length:685 Species:Drosophila melanogaster


Alignment Length:495 Identity:87/495 - (17%)
Similarity:163/495 - (32%) Gaps:166/495 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 FGYDISDYKAIQPEYGTMQDFEELIDTAFELGIKVVLDFVPNHSSDQHEWFKKSAAREPGYEDFY 154
            |||.::.:.|....||..:..:.:||.|...|:.|:||.|.:|:|...:                
  Fly   234 FGYQVTSFYAASSRYGNPEQLKRMIDVAHSHGLFVLLDVVHSHASKNVQ---------------- 282

  Fly   155 VWHDGIVQENGTRVPPNNWPSVFYGSAWEWHEG-REQYYLHQFTKEQPDLNYRNPKVVQAMDDVL 218
               ||:.|.:||.       |.|:      |:| |.::.|.    :....||...:|::.:...|
  Fly   283 ---DGLNQFDGTN-------SCFF------HDGARGEHSLW----DSRLFNYVEYEVLRFLLSNL 327

  Fly   219 LFWLNK-GVAGFRIDAVNHLFEDESLKDEPLSGK---------TTDSLSYDYTKHIYSRDLPEVL 273
            .:|.:: ...|:|.|.|..:........|..||.         .||:|:|              |
  Fly   328 RWWHDEYNFDGYRFDGVTSMLYHSRGIGEGFSGDYNEYFGLNVDTDALNY--------------L 378

  Fly   274 EMIHHWRQLLDDFSAKHPERPTRIM-MTEAYAGLTQLADYYEDSNGVRGSHLPFNFHFITDVKGD 337
            .:.:|....:|          :||: :.|..:|:..|.      ..|....:.|::.....:.  
  Fly   379 GLANHLLHTID----------SRIITIAEDVSGMPTLC------RPVSEGGIGFDYRLGMAIP-- 425

  Fly   338 SDARDYVYNVEKWLIYMPRGHAANWVMGN--------------------HDNPRVASRF------ 376
                      :||:..:.......|.|||                    ||...|..:.      
  Fly   426 ----------DKWIELLKEQSDDEWDMGNLVHTLTNRRWMENTVAYAESHDQALVGDKTIAFWLM 480

  Fly   377 --------------------GPASVDAMNMLLLTLPGVA-VTYNGEELGMVDYRELSWEETVDPP 420
                                |.|....:.::...|.|.| :.:.|.|.|..::  |.:....:..
  Fly   481 DKEMYTHMSTLSDSSVIIDRGLALHKMIRLITHALGGEAYLNFMGNEFGHPEW--LDFPRVGNND 543

  Fly   421 ARNVGEKLYQEVSRDPVRTPFQWNNETNAGFSTAAKT--WLPVHPNYLELNLEAQKVANRSHYQV 483
            :.:...:.:..|..|.::  :::.||.:...:.|.:.  ||...|.::....|..|:        
  Fly   544 SYHYARRQWNLVDDDLLK--YKYLNEFDRAMNEAEERYGWLHSGPAWVSWKHEGDKI-------- 598

  Fly   484 YKDLLELRKSAIMRVGRFNIEPL---------TRWVFAFK 514
                :...::.::.|  ||..|.         |.|...::
  Fly   599 ----IAFERAGLVFV--FNFHPQQSFTGYRVGTNWAGTYQ 632

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mal-B2NP_001188791.2 AmyAc_maltase 33..502 CDD:200467 82/472 (17%)
Malt_amylase_C 510..>541 CDD:351862 0/5 (0%)
AGBENP_788342.1 GlgB 52..682 CDD:223373 87/495 (18%)
E_set_GBE_euk_N 62..161 CDD:199884
AmyAc_bac_euk_BE 167..570 CDD:200460 75/417 (18%)
Alpha-amylase_C 588..683 CDD:280898 8/59 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45443595
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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