Protein Alignment Mal-B2 and AMY1A

DIOPT Version :9

• Sequence 1: NP_001188791.2
• Gene: Mal-B2 / 34598
• FlyBaseID: FBgn0032382
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001008222.1
• Gene: AMY1A / 276
• HGNCID: 474
• Length: 511
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 107/564 - (18%)
• Similarity: 174/564 - (30%)
• Gaps: 259/564 - (45%)

  Fly    67 RYLADTGITATWLSP-----IFQSPMIDF--GYDISDYKAIQPEYGTMQDFEELIDTAFELGIKV 124
            ||||..|.....:||     ...:|...:  .|....|| :....|...:|..::.....:|:::
Human    45 RYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYK-LCTRSGNEDEFRNMVTRCNNVGVRI 108

  Fly   125 VLDFVPNH----------SSDQHEWFKKSAAREPGYEDFYVWHDGIVQENGTRVPPNNWPSVFYG 179
            .:|.|.||          ||....:|      .||..||                    |:|.|
Human   109 YVDAVINHMCGNAVSAGTSSTCGSYF------NPGSRDF--------------------PAVPY- 146

  Fly   180 SAWEWHEGR--------EQYYLHQFTKEQP-------DL----NYRNPKVVQAMDDVLLFWLNKG 225
            |.|::::|:        |.|  :..|:.:.       ||    :|...|:.:.|:.:    ::.|
Human   147 SGWDFNDGKCKTGSGDIENY--NDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHL----IDIG 205

  Fly   226 VAGFRIDAVNHLFEDESLKDEPLSGKTTDSLSYDYTKHIYSRDLPEVLEMIHHWRQLLDDFSAKH 290
            ||||||||                           :||::..|:..:|:.:|:.
Human   206 VAGFRIDA---------------------------SKHMWPGDIKAILDKLHNL----------- 232

  Fly   291 PERPTRIMMTEAYAGLTQLADYYEDSNGVRGSHLPFNFHFITDVKGDS-DARDYVYN-------- 346
                                    :||.......||.:..:.|:.|:. .:.||..|
Human   233 ------------------------NSNWFPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKY 273

  Fly   347 -------VEKW----LIYMPRGHAANWVMG--------------NHDNPRVASRFGPASV----- 381
                   :.||    :.|:     .||..|              ||||.| ....|.||:
Human   274 GAKLGTVIRKWNGEKMSYL-----KNWGEGWGFMPSDRALVFVDNHDNQR-GHGAGGASILTFWD 332

  Fly   382 -----DAMNMLLLTLPG---VAVTY-------NGEELGMVDYRELSWEETVDPPARNVGEKLYQE 431
                 .|:..:|....|   |..:|       ||:::.       .|   |.||..|   .:.:|
Human   333 ARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVN-------DW---VGPPNDN---GVTKE 384

  Fly   432 VSRDPVRTPFQWNNETNAGFSTAAKTWLPVHPNYLELNLEAQKVANRSHYQVYKDLLELRKSAIM 496
            |:.:|         :|..|     ..|:..|                 .::..::::..|
Human   385 VTINP---------DTTCG-----NDWVCEH-----------------RWRQIRNMVNFR----- 413

  Fly   497 RVGRFNI---EPLTRWV------FAFKRSYPNFESIITVINVSD 531
                 |:   :|.|.|.      .||.|....|    .|.|..|
Human   414 -----NVVDGQPFTNWYDNGSNQVAFGRGNRGF----IVFNNDD 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-B2	NP_001188791.2	AmyAc_maltase	33..502	CDD:200467	96/524 (18%)
		Malt_amylase_C	510..>541	CDD:351862	7/28 (25%)
AMY1A	NP_001008222.1	AmyAc_bac_euk_AmyA	25..416	CDD:200456	97/526 (18%)
		Aamy_C	422..510	CDD:214749	9/31 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740