Protein Alignment Mal-B2 and Slc3a1

DIOPT Version :9

• Sequence 1: NP_001188791.2
• Gene: Mal-B2 / 34598
• FlyBaseID: FBgn0032382
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_033231.2
• Gene: Slc3a1 / 20532
• MGIID: 1195264
• Length: 685
• Species: Mus musculus
• Alignment Length: 593
• Identity: 209/593 - (35%)
• Similarity: 323/593 - (54%)
• Gaps: 54/593 - (9%)

  Fly     5 LIQILLFSLLNSGSIMAGLVKSDTEDFIDWWPHTVFYQIYPRSFKDSNGDGIGDLKGITSKLRYL 69
            |..:.:|.|:  |:.:|.:|.|  ...:|||.....|||||||||||:.||.||||||..||.|:
Mouse    91 LTVVSVFLLI--GATIAIIVIS--PKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYI 151

  Fly    70 ADTGITATWLSPIFQSPMIDFGYDISDYKAIQPEYGTMQDFEELIDTAFELGIKVVLDFVPNHSS 134
            ....|...|::..::|.:.||.|.:.|:|.|.|.:|||:|||.|:....:.|:|:::||:|||:|
Mouse   152 TALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTS 216

  Fly   135 DQHEWFKKSAAREPGYEDFYVWHDGIVQENGTRVPPNNWPSVFYGSAWEWHEGREQYYLHQFTKE 199
            |:|.||:.|..|...|.|:|:||: ....||...|||||.||:..|:|.:.|.|:|.|.|||.||
Mouse   217 DKHPWFQSSRTRSGKYTDYYIWHN-CTHVNGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKE 280

  Fly   200 QPDLNYRNPKVVQAMDDVLLFWLNKGVAGFRIDAVNHLFEDESLKDE--PLSGKTTDSLS-YDYT 261
            |||||:|||.|.:.:.:::.|||:|||.||..|||..|.|.:.|::|  ..:.:..|::: |...
Mouse   281 QPDLNFRNPAVQEEIKEIITFWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTSQIPDTVTHYSEL 345

  Fly   262 KHIYSRDLPEVLEMIHHWRQLLDDFSAKHPERPTRIMMTEAYAGLTQLADYYEDSNGVRGSHLPF 326
            .|.::.....:.:::..:||.::.:| :.|.| .|.|..||.|...:....|.....::.:..||
Mouse   346 YHDFTTTQVGMHDIVRDFRQTMNQYS-REPGR-YRFMGAEASAESIERTMMYYGLPFIQEADFPF 408

  Fly   327 NFHFIT--DVKGDSDARDYVYNV-EKWLIYMPRGHAANWVMGNHDNPRVASRFGPASVDAMNMLL 388
            |.:|.|  .:.|.:     ||.| ..|:..||.|...||:.|..:.||:.||.|...|:||:|||
Mouse   409 NKYFTTIGTLSGHT-----VYEVITSWMENMPEGKWPNWMTGGPETPRLTSRVGSEYVNAMHMLL 468

  Fly   389 LTLPGVAVTYNGEELGMVDYRELSWEETVDPPARNVGEKLYQEVSRDPVRTPFQWNNETNAGFST 453
            .||||..:||.|||:||.|....::.|:.|....         ||    ::|.||:|.:||||:.
Mouse   469 FTLPGTPITYYGEEIGMGDISVTNFNESYDSTTL---------VS----KSPMQWDNSSNAGFTE 520

  Fly   454 AAKTWLPVHPNYLELNLEAQKVANRSHYQVYKDLLELRKSAIMRVGRFNIEPLTRWVF------- 511
            |..||||.:.:|..:|::.||....|..::|:||..|..:.::         |:|..|
Mouse   521 ANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATELV---------LSRGWFCLLRDDS 576

  Fly   512 ---AFKRSYPNFESI-ITVINVSDKEQLVDLSEFLSQ-PKKLVVEVSGVDSKYQPGQSLAASALL 571
               .:.|.....::: :.|:|..:...:::|...:|. |.:|.:.:|  .:....|.::...|:.
Mouse   577 HSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLS--TNSASKGSAVDTRAIS 639

  Fly   572 LAAREGLV 579
            |...||||
Mouse   640 LEKGEGLV 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-B2	NP_001188791.2	AmyAc_maltase	33..502	CDD:200467	184/474 (39%)
		Malt_amylase_C	510..>541	CDD:351862	5/41 (12%)
Slc3a1	NP_033231.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53
		SLC3A2_N	64..122	CDD:292647	10/34 (29%)
		AmyAc_SLC3A1	115..568	CDD:200494	186/482 (39%)
		trehalose_treC	116..604	CDD:274115	189/517 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833817
Domainoid	1	1.000	276	1.000	Domainoid score	I1723
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37289
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2073
Isobase	1	0.950	-	0.709012	Normalized mean entropy	S2995
OMA	1	1.010	-	-		QHG53234
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000282
OrthoInspector	1	1.000	-	-		otm42374
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10357
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R680
SonicParanoid	1	1.000	-	-		X202
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.880