Protein Alignment Mal-B1 and IMA5

DIOPT Version :9

• Sequence 1: NP_609522.1
• Gene: Mal-B1 / 34597
• FlyBaseID: FBgn0032381
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_012319.1
• Gene: IMA5 / 853214
• SGDID: S000003752
• Length: 581
• Species: Saccharomyces cerevisiae
• Alignment Length: 611
• Identity: 189/611 - (30%)
• Similarity: 290/611 - (47%)
• Gaps: 112/611 - (18%)

  Fly    33 WWQHEVFYQIYPRSFQDSNGDGIGDLQGITSRLQYFKDTGITSVWLSPIYESPMVDFGYDISNYT 97
            ||:....|||||.||:|||.||.|||.||||:|.|.|:.|:.::|:.|.|:||..|.||||:||.
Yeast     9 WWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANYE 73

  Fly    98 NIQPEYGTLEDFDALIAKANELGVKVILDFVPNHSSNKHPWFIKSVAREPG-YEDFYVWE----- 156
            .:.|.|||.||...:|.:|::.|:|||:|.|.||.|.:|.||.:|.:.:.. ..|::.|.
Yeast    74 KVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANPKRDWFFWRPPKGY 138

  Fly   157 DGILLENGTRVPPNNWLSVFSGSAWMWNDERQQYYLRQFTYGQPDLNYRNPAVIKAM-DDVMLFW 220
            |    |.|..:|||||.|.|.||||.::::..:::|..|..||||.|:.|....||: |..:.:|
Yeast   139 D----EKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWENEECRKAIYDSSVGYW 199

  Fly   221 LNKGIAGFRIDAIIYIYEDAQ-LRDEPPSGTT-----------DDPNNEAYLS--HIYTRNQ-PE 270
            |...:.||||| :..:|...: |.|.|.:..|           :.|....|..  |.|..:| ||
Yeast   200 LRHNVDGFRID-VGSMYSKVEGLPDAPITDPTVPYQKGTEFFINGPRIHEYHKEMHNYMLSQVPE 263

  Fly   271 DYGLLQHWRQLLDN------YTANHDGPLRIMMTEGYASVSQLME-YYEDSNGVQGPQFPFNF-D 327
            ...::......:.|      ||:..:|.|.:|....:.||.:..: .||        ..||.. |
Yeast   264 GKEIMTVGEVGIGNEDDFRVYTSAKEGELNMMFNFKHTSVGENPKCKYE--------LIPFTLKD 320

  Fly   328 FITELNANSTAADFVFYISR--W-LIYMPHGHVANWVMGNHDNPRVASRFG-------EKSVDAM 382
            |...|     |..|:|..:.  | .||:.          |||.||..||||       |.|...:
Yeast   321 FKLAL-----AESFLFIENTDCWSTIYLE----------NHDQPRSVSRFGSDSPKWREISSKML 370

  Fly   383 NMLLMTLPGIGITYNGEELGMTDYRDISWSDTVDQPACEAGIDNYKT------------------ 429
            ..|:::|.|....|.|:||||.:::    :..::|..|..|...|..
Yeast   371 ATLIISLTGTVFIYQGQELGMPNFK----NRKIEQIKCVEGTGTYAAIKRDYGEDSEKMKKFFEA 431

  Fly   430 ---ISRDPERTPMQWSSD-VNAGFSSADRTWLPVNPNYKE-LNLRNQQQARRSHYKIYQSLLKLR 489
               ||||..|||..||:| .:||||...:.|:.:|.:::: :|...:.:.:.|.:..::..|::|
Yeast   432 LALISRDHGRTPFPWSADEPSAGFSKDAKPWIDMNESFRDGINAEAELKDKNSVFFFWKKALQVR 496

  Fly   490 Q-----LPVLKNGSFVPEVVNRRVFAFKRELKNEHTLLTIVNVSNRTELVDIADFIEQPNRLSVL 549
            :     |....|..|: ::.|.::|.|.::..|: .:..:.|.|:     |..||....|..|..
Yeast   497 KEHKDILVYGHNFQFI-DLDNDKLFMFTKDTDNK-KMFAVFNFSS-----DNTDFSVPDNEASYT 554

  Fly   550 VAGVDSQHRVGDRLKAETIELAPNEG 575
            :...:..:..||   :.|::  |.||
Yeast   555 MFFGNYANSNGD---SRTLQ--PWEG 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-B1	NP_609522.1	AmyAc_maltase	30..500	CDD:200467	171/534 (32%)
		trehalose_treC	33..538	CDD:274115	179/572 (31%)
IMA5	NP_012319.1	AmyAc_SI_OligoGlu_DGase	11..498	CDD:200472	167/518 (32%)
		Malt_amylase_C	509..>548	CDD:413446	10/45 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342200
Domainoid	1	1.000	192	1.000	Domainoid score	I624
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	257	1.000	Inparanoid score	I641
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000282
OrthoInspector	1	1.000	-	-		mtm9159
orthoMCL	1	0.900	-	-		OOG6_100402
Panther	1	1.100	-	-	O	PTHR10357
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X202
TreeFam	0	0.000	Not matched by this tool.
	11	10.790