Protein Alignment Mal-B1 and SLC3A2

DIOPT Version :9

• Sequence 1: NP_609522.1
• Gene: Mal-B1 / 34597
• FlyBaseID: FBgn0032381
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001012680.1
• Gene: SLC3A2 / 6520
• HGNCID: 11026
• Length: 631
• Species: Homo sapiens
• Alignment Length: 590
• Identity: 117/590 - (19%)
• Similarity: 199/590 - (33%)
• Gaps: 186/590 - (31%)

  Fly    13 GLVGILAHKHQSKELDAKYNWWQHEVFYQIYPRSFQDSNGDGIGDLQGITSRLQYFKDTGITSVW 77
            |.|.|:....:.:||.|: .||.....|:|  ...|...|.|.|:|.|:..||.|.....:..:.
Human   200 GAVVIIVRAPRCRELPAQ-KWWHTGALYRI--GDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLV 261

  Fly    78 LSPIYESPMVDFGYDISNYTNIQPEYGTLEDFDALIAKANELGVKVILDFVPNHSSNKHPWFIKS 142
            |.||:::...|...  ::...|.|.:|:.||||:|:..|.:..::||||..||:...
Human   262 LGPIHKNQKDDVAQ--TDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGE-------- 316

  Fly   143 VAREPGYEDFYVWEDGILLENGTRVPPNNWLSVFSGSAWMWNDERQQYYLRQFTYGQPDLNYRNP 207
                                       |:|.|.                       |.|
Human   317 ---------------------------NSWFST-----------------------QVD------ 325

  Fly   208 AVIKAMDDVMLFWLNKGIAGFRI-------DAIIYIYEDAQLRDEPPSGTTDDPNNEAYLSHIYT 265
            .|...:.|.:.|||..|:.||::       ||..::.|...:                      |
Human   326 TVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNI----------------------T 368

  Fly   266 RNQPEDYGLL-----QHWRQLLDNYTANHDGPLRIMMTEGYASVSQLMEYYEDSNGVQGPQFPFN 325
            :...||..|:     ...:|:|....:|.|    :::|..|.|.|             |......
Human   369 KGFSEDRLLIAGTNSSDLQQILSLLESNKD----LLLTSSYLSDS-------------GSTGEHT 416

  Fly   326 FDFITE-LNANSTAADFVFYISRWLIYMPHGHVANWVMGNHDNPRVASRF-GEKSVDAMNMLLMT 388
            ...:|: |||..         :||         .:|.:   ...|:.:.| ..:.:....::|.|
Human   417 KSLVTQYLNATG---------NRW---------CSWSL---SQARLLTSFLPAQLLRLYQLMLFT 460

  Fly   389 LPGIGITYNGEELGMTDYRDISWSDTVDQPACEAGIDNYKTISRDPERTP-MQWSSDVNAGFSSA 452
            |||..:...|:|:|:         |....|.             .|...| |.|
Human   461 LPGTPVFSYGDEIGL---------DAAALPG-------------QPMEAPVMLW----------- 492

  Fly   453 DRTWLPVNPNYKELNL--RNQQQARRSHYKIYQSLLKLRQLP-VLKNGSFVPEVVNRRVFAFKRE 514
            |.:..|..|.....|:  :.|.:...|...:::.|...|... .|.:|.|........:|::.|.
Human   493 DESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRH 557

  Fly   515 LKNEHTLLTIVN-----VSNRTELVDIADFIEQPNRLSVLVAGVDSQHRVGDRLKAETIELAPNE 574
            .......|.::|     :|...:..|:......|.:..:|::....:.. |..|:.|.::|.|:|
Human   558 WDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREE-GSPLELERLKLEPHE 621

  Fly   575 GLVIQ 579
            ||:::
Human   622 GLLLR 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-B1	NP_609522.1	AmyAc_maltase	30..500	CDD:200467	94/487 (19%)
		trehalose_treC	33..538	CDD:274115	101/527 (19%)
SLC3A2	NP_001012680.1	SLC3A2_N	161..225	CDD:292647	8/25 (32%)
		AmyAc_SLC3A2	208..537	CDD:200483	95/490 (19%)
		AmyA	238..597	CDD:223443	96/517 (19%)
		DUF3459	520..625	CDD:288769	21/105 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384693at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750