Protein Alignment Mal-B1 and Slc3a1

DIOPT Version :9

• Sequence 1: NP_609522.1
• Gene: Mal-B1 / 34597
• FlyBaseID: FBgn0032381
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_033231.2
• Gene: Slc3a1 / 20532
• MGIID: 1195264
• Length: 685
• Species: Mus musculus
• Alignment Length: 592
• Identity: 210/592 - (35%)
• Similarity: 326/592 - (55%)
• Gaps: 46/592 - (7%)

  Fly     1 MVVVKIAFILSVGLVGILAHKHQSKELDAKYNWWQHEVFYQIYPRSFQDSNGDGIGDLQGITSRL 65
            :.||.: |:|....:.|:.  ...|.||    |||....||||||||:||:.||.|||:||..:|
Mouse    91 LTVVSV-FLLIGATIAIIV--ISPKCLD----WWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKL 148

  Fly    66 QYFKDTGITSVWLSPIYESPMVDFGYDISNYTNIQPEYGTLEDFDALIAKANELGVKVILDFVPN 130
            .|.....|.::|::..|:|.:.||.|.:.::..|.|.:||::||:.|:|..::.|:|:|:||:||
Mouse   149 DYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPN 213

  Fly   131 HSSNKHPWFIKSVAREPGYEDFYVWEDGILLENGTRVPPNNWLSVFSGSAWMWNDERQQYYLRQF 195
            |:|:|||||..|..|...|.|:|:|.:...: ||...||||||||:..|:|.:::.|:|.|..||
Mouse   214 HTSDKHPWFQSSRTRSGKYTDYYIWHNCTHV-NGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQF 277

  Fly   196 TYGQPDLNYRNPAVIKAMDDVMLFWLNKGIAGFRIDAIIYIYEDAQLRDEPPSGTTDDPNNEAYL 260
            ...|||||:|||||.:.:.:::.|||:||:.||..||:.::.|...||:|....|:..|:...:.
Mouse   278 LKEQPDLNFRNPAVQEEIKEIITFWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTSQIPDTVTHY 342

  Fly   261 SHIY---TRNQPEDYGLLQHWRQLLDNYTANHDGPLRIMMTEGYA-SVSQLMEYYEDSNG---VQ 318
            |.:|   |..|...:.:::.:||.::.| :...|..|.|..|..| |:.:.|.||    |   :|
Mouse   343 SELYHDFTTTQVGMHDIVRDFRQTMNQY-SREPGRYRFMGAEASAESIERTMMYY----GLPFIQ 402

  Fly   319 GPQFPFNFDFITELNANSTAADFVFY--ISRWLIYMPHGHVANWVMGNHDNPRVASRFGEKSVDA 381
            ...||||..|.|    ..|.:....|  |:.|:..||.|...||:.|..:.||:.||.|.:.|:|
Mouse   403 EADFPFNKYFTT----IGTLSGHTVYEVITSWMENMPEGKWPNWMTGGPETPRLTSRVGSEYVNA 463

  Fly   382 MNMLLMTLPGIGITYNGEELGMTDYRDISWSDTVDQPACEAGIDNYKTISRDPERTPMQWSSDVN 446
            |:|||.||||..|||.|||:||.|....:::::.|.....:             ::||||.:..|
Mouse   464 MHMLLFTLPGTPITYYGEEIGMGDISVTNFNESYDSTTLVS-------------KSPMQWDNSSN 515

  Fly   447 AGFSSADRTWLPVNPNYKELNLRNQQQARRSHYKIYQ--SLLKLRQLPVLKNGSFVPEVVNRRVF 509
            |||:.|:.||||.|.:|..:|:..|:....|..::||  |||...:| ||..|.|.....:....
Mouse   516 AGFTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATEL-VLSRGWFCLLRDDSHSV 579

  Fly   510 AFKRELKN-EHTLLTIVNVSNRTELVDIADFI-EQPNRLSVLVAGVDSQHRVGDRLKAETIELAP 572
            .:.|||.. ::..|.::|....:.::::...| :.|..|.:.:: .:|..: |..:....|.|..
Mouse   580 VYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLS-TNSASK-GSAVDTRAISLEK 642

  Fly   573 NEGLVIQ 579
            .||||::
Mouse   643 GEGLVLE 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-B1	NP_609522.1	AmyAc_maltase	30..500	CDD:200467	185/480 (39%)
		trehalose_treC	33..538	CDD:274115	191/516 (37%)
Slc3a1	NP_033231.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53
		SLC3A2_N	64..122	CDD:292647	11/37 (30%)
		AmyAc_SLC3A1	115..568	CDD:200494	185/480 (39%)
		trehalose_treC	116..604	CDD:274115	191/511 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833818
Domainoid	1	1.000	276	1.000	Domainoid score	I1723
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37289
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2073
Isobase	1	0.950	-	0.709012	Normalized mean entropy	S2995
OMA	1	1.010	-	-		QHG53234
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000282
OrthoInspector	1	1.000	-	-		otm42374
orthoMCL	1	0.900	-	-		OOG6_100402
Panther	1	1.100	-	-	O	PTHR10357
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X202
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.750