DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mal-B1 and C50B6.7

DIOPT Version :9

Sequence 1:	NP_609522.1	Gene:	Mal-B1 / 34597	FlyBaseID:	FBgn0032381	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_506303.1	Gene:	C50B6.7 / 179813	WormBaseID:	WBGene00008220	Length:	713	Species:	Caenorhabditis elegans

Alignment Length:	435	Identity:	87/435 - (20%)
Similarity:	140/435 - (32%)	Gaps:	192/435 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LQYFKDTGITSVWLSPIYESPMVDF-GYDISNY---TNIQP-------EYGTLEDFDALIAKANE 118
            |||:   |..:|.:||    ||... .:..:||   ...||       ..|..::|..::.:.|:
Worm    53 LQYY---GYGAVQVSP----PMEHLKAFPNNNYPWWVRYQPVSYKLDSRSGNEQEFQDMVNRCNK 110

  Fly   119 LGVKVILDFVPNHSSNKHPWFIKSVAREPGYEDFYVWEDGILLENGTRVPPNNWLSVFSGSAWMW 183
            :||::|:|.|.||        :..:.::.|              ||.   .::..|.|.|:..:.
Worm   111 VGVRIIVDIVMNH--------MVGIGQKSG--------------NGV---GSSGSSSFDGTHGVQ 150

  Fly   184 NDERQQYYLRQFT-------------------------YGQPDLNYRNPAVIKAMDDVMLFWLNK 223
            :.....|.|..|.                         .|..|||..: |.::|.   ::.:|||
Worm   151 SFPGVPYSLGDFNNPKCDGDIQGSDYQNSAEHVKDCRLVGLLDLNQAS-ATVRAK---IVAYLNK 211

  Fly   224 ----GIAGFRIDA--------IIYIYEDAQ-LR------DEPPSGTTD--DPNNEA--------- 258
                |:||||.||        |:.|..|.: ||      ::.|....:  |...||
Worm   212 LVDMGVAGFRHDASKHMWPQDILNILNDVKDLRSDIYGSNQRPFAVHEVIDRGGEAVKCGDYFGN 276

  Fly   259 -----------------------YLSHI---YTRNQPEDYGLLQHWRQLLDNYTANHDGPLRIMM 297
                                   ||:::   |.....||:.:|        |:..|||
Worm   277 GRYTNFNFGAAVSAAAKQQSDWKYLANLGPGYGYGNNEDHDVL--------NFIDNHD------- 326

  Fly   298 TEGYASVSQLMEYYEDSNGVQGPQFPFNFDFITELNANSTAADFVFYISRWLIYMPHGHVANWVM 362
              .....|..:..|:|     |.::.....|                    ::..|:|:
Worm   327 --NQRDSSPYVVTYKD-----GQKYNLAVGF--------------------MLAWPYGY------ 358

  Fly   363 GNHDNPRVASRFGEKSVD-------AMNMLLMTLPGIGITYNGEE 400
                 |||.|.|.....|       |.|....|.|    |:||::
Worm   359 -----PRVMSSFAFSYSDQSPPNSGASNDYATTSP----TFNGDQ 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mal-B1	NP_609522.1	AmyAc_maltase	30..500	CDD:200467	87/435 (20%)
Mal-B1	NP_609522.1	trehalose_treC	33..538	CDD:274115	87/435 (20%)
C50B6.7	NP_506303.1	AmyAc_bac_euk_AmyA	31..421	CDD:200456	87/435 (20%)
		AmyA	53..>354	CDD:223443	72/378 (19%)
		Aamy_C	432..511	CDD:214749
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900