Protein Alignment esc and escl

DIOPT Version :10

• Sequence 1: NP_477431.1
• Gene: esc / 34595
• FlyBaseID: FBgn0000588
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_557691.4
• Gene: escl / 3291747
• VectorBaseID: AGAMI1_011901
• Length: 426
• Species: Anopheles gambiae
• Alignment Length: 418
• Identity: 218/418 - (52%)
• Similarity: 287/418 - (68%)
• Gaps: 4/418 - (0%)

  Fly     4 DKVKNGNEPEESEESCGDESASYTTNSTTSRSKSPSSSTRSKRRGRRSTKSKPKS--RAAYKYDT 66
            ::..|..:.:.|||...:...:.:..||.:.:.|..|.|:..||.||.:|.|.:.  :..:|:.|
Mosquito     7 EEAANNTQGDASEEEDDEMHETSSMGSTCTDNTSNGSETQINRRKRRRSKKKQQKTVKPIFKFST 71

  Fly    67 HVKENHGANIFGVAFNTLLGKDEPQVFATAGSNRVTVYECPRQGGMQLLHCYADPDPDEVFYTCA 131
            :|||:||.::||..||..|...|...|||.||||||:|:|...||:.|..||||||.:|||||||
Mosquito    72 YVKEDHGQSLFGCLFNYNLKNGELPTFATVGSNRVTIYQCQNDGGITLKQCYADPDNEEVFYTCA 136

  Fly   132 WSYDLKTSSPLLAAAGYRGVIRVIDVEQNEAVGNYIGHGQAINELKFHPHKLQLLLSGSKDHAIR 196
            ||:|..|.||||||.|.|||:||.:....|....|||||.||||:||||.:..||:|.||||::|
Mosquito   137 WSHDADTGSPLLAAGGLRGVLRVFNTASLEGHKYYIGHGHAINEVKFHPKEPYLLMSASKDHSLR 201

  Fly   197 LWNIQSHVCIAILGGVEGHRDEVLSIDFNMRGDRIVSSGMDHSLKLWCLNTPEFHHKIELSNTFS 261
            |||.::.:|||:.||||||||||||.||:::|.|.:|.|||||||:|.|:|....:.|..|.||:
Mosquito   202 LWNTKTDICIAVFGGVEGHRDEVLSFDFDIQGRRFMSCGMDHSLKMWRLDTETMKNAIRNSYTFN 266

  Fly   262 QEKSTLPFPTVTKHFPDFSTRDIHRNYVDCVQWFGNFVLSKSCENAIVCWKPGQLHQSFEQVKPS 326
            :.|:...||:|.:|||.||||||||||||||:|.|:|||||||:|.|||||||:|..  .:||.:
Mosquito   267 EAKNLSRFPSVNEHFPVFSTRDIHRNYVDCVRWMGDFVLSKSCQNTIVCWKPGRLED--VEVKQN 329

  Fly   327 DSSCTIIAEFEYDECEIWFVRFGFNPWQKVIALGNQQGKVYVWELDPSDPEGAHMTTLHNSRSVA 391
            ::..|||...||.||.||||||..:.|||.:|||||.|:.|:||||..||.....:||::.:...
Mosquito   330 ETVTTIITTLEYSECIIWFVRFSLDYWQKYLALGNQTGRTYIWELDTDDPVHPRCSTLYHPKCTT 394

  Fly   392 TVRQIAFSRDASVLVYVCDDATVWRWNR 419
            .:||.||||..::|:.||||.|||||::
Mosquito   395 PIRQTAFSRSGNILICVCDDGTVWRWDK 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esc	NP_477431.1	WD40	72..420	CDD:441893	198/348 (57%)
		WD40 repeat	76..122	CDD:293791	24/45 (53%)
		WD40 repeat	128..168	CDD:293791	22/39 (56%)
		WD40 repeat	173..210	CDD:293791	21/36 (58%)
		WD40 repeat	220..282	CDD:293791	30/61 (49%)
		WD40 repeat	289..337	CDD:293791	27/47 (57%)
		WD40 repeat	345..386	CDD:293791	22/40 (55%)
		WD40 repeat	393..417	CDD:293791	14/23 (61%)
escl	XP_557691.4	None