DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pde1c and Pde7a

DIOPT Version :9

Sequence 1:	NP_001137817.1	Gene:	Pde1c / 34594	FlyBaseID:	FBgn0264815	Length:	1173	Species:	Drosophila melanogaster
Sequence 2:	NP_112342.1	Gene:	Pde7a / 81744	RGDID:	68391	Length:	482	Species:	Rattus norvegicus

Alignment Length:	351	Identity:	110/351 - (31%)
Similarity:	171/351 - (48%)	Gaps:	28/351 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   671 SEVQPDAVPPEVREWLASTFTRQMATSRRKSDEKPKFRSVAHAIRAGIFVDRMYRRVSSSALTAF 735
            ||::.......:|..|  :|.|.:.:||        |...|...|:...:|..|...:..
  Rat    97 SEIEASVSARNIRRLL--SFQRYLRSSR--------FFRGATVCRSLNILDEDYNGQAKC----- 146

  Fly   736 PPDVVRLLKNLDDWTFDVFALTEAASGQVVKYVAYELFNRYGSIHKFKIAPGILEAFLHRVEEGY 800
                  :|:.:.:|.||:|......:|..:..:.:.||:.:|.|..|.:....|..||..::|.|
  Rat   147 ------MLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDY 205

  Fly   801 CRYRNPYHNNLHAVDVMQTIHYCLCNTGLMNWLTDLEIFASLLAALLHDYEHTGTTNNFHVMSGS 865
             ..:|||||.:||.||.|.:|..|....|.|.:|..:|..||:||..||.:|.|....|.:.:..
  Rat   206 -HSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNH 269

  Fly   866 ETALLYNDRAVLENHHASASFRLLREDEYNILSHLSREEFRELRGLVIEMVLGTDMTNHFQQMKA 930
            ..|.||.:.:||||||..::..||||.  .:.|||..|...|:...:..::|.||::...:.:..
  Rat   270 YLATLYKNTSVLENHHWRSAVGLLRES--GLFSHLPLESRHEMEAQIGALILATDISRQNEYLSL 332

  Fly   931 MRQLLTLQEATID----KQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLEEFFRQGDLEKELGLP 991
            .|..|...:..:|    :..||.:.|.|.||.:|.:.|.:..:|:..:.||||.|||:||:..|.
  Rat   333 FRSHLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLG 397

  Fly   992 FSPLCDRNNTLVAESQICFIDFIVEP 1017
            .||||||....:|..||.|:.::|||
  Rat   398 VSPLCDRQTESIANIQIGFMTYLVEP 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pde1c	NP_001137817.1	PDEase_I_N	666..722	CDD:285672	11/50 (22%)
Pde1c	NP_001137817.1	PDEase_I	807..1026	CDD:278654	79/215 (37%)
Pde7a	NP_112342.1	PDEase_I	211..431	CDD:395177	79/215 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920