Protein Alignment Pde1c and pde9aa

DIOPT Version :10

• Sequence 1: NP_001137817.1
• Gene: Pde1c / 34594
• FlyBaseID: FBgn0264815
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: XP_009302928.2
• Gene: pde9aa / 799942
• ZFINID: ZDB-GENE-130920-1
• Length: 509
• Species: Danio rerio
• Alignment Length: 462
• Identity: 117/462 - (25%)
• Similarity: 206/462 - (44%)
• Gaps: 72/462 - (15%)

  Fly   661 TRLADEDDELSEVQPDAVPPEVREW----LASTFTRQMATSRRKSD-------EKPKFRSVAHAI 714
            ::|||:::....|.........|.:    |.:..|.::|...::.:       |..|.||....:
Zfish    82 SQLADKEELFQNVLTQVAEQFSRAFKINELKTEVTNRLAMLEKRVELEGMKVVEIEKCRSDIKKL 146

  Fly   715 RAGIFVDRMYRRVSSSAL------------TAFP-----PDVVRLLKN--LDDWTFDVFALTEAA 760
            |     :.|..|.:||.|            .::|     .|.|..||.  .|.|.::
Zfish   147 R-----EEMASRNNSSFLEDNKKLTPRRDVPSYPKYHLSQDTVEALKQPLFDVWQWE-------- 198

  Fly   761 SGQVVKYVAYELFNRYGSIHKFKIAPGILEAFLHRVEEGYCRYRNPYHNNLHAVDVMQTIHYCLC 825
            |.:::..:.: :::..|.:..|.|.|..|:.:|..:.:.|  ..||:||..|...|.|.::..:.
Zfish   199 SNEMLSCLEH-MYHDLGLVKDFNINPITLKRWLLCIHDNY--RNNPFHNFRHCFCVTQMMYSMIY 260

  Fly   826 NTGLMNWLTDLEIFASLLAALLHDYEHTGTTNNFHVMSGSETALLYNDRAVLENHHASASFRLLR 890
            ..||....|.::|...:.||:.||.:|.|..|.:.:.:.:|.|:.|||.:.|||||.:.:|::..
Zfish   261 LCGLQEKFTQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFS 325

  Fly   891 EDEYNILSHLSREEFRELRGLVIEMVLGTDMTNHFQQMKAMRQLLTLQEATIDKQ-KVLSLVL-H 953
            :.:.||.:....|.|:::|...|.::|.|||..|.:.|.:.:|.:...:...::. ..|.:|| .
Zfish   326 QPDCNIFASFDPEAFKQIRQGTITLILATDMARHGEIMDSFKQKVDSFDYNNEEHVTCLKMVLIK 390

  Fly   954 CCDISHPAKQWGVHHRWTMLLLEEFFRQGDLEKELGLPFSPLCDRNNTLVAESQICFIDFIVEPS 1018
            |||||:..:...|...|...||||:|.|.|.||..|||.:|..||.......:||.||.|::.|.
Zfish   391 CCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKAEGLPVAPFMDREKVTKPTAQIGFIKFVLIPM 455

  Fly  1019 ----MGVMSDMLELILAPIAPMNKSKPATLVEHETTANSTTNSAIVIPNSGITPSMDKPRDHRTE 1079
                |.:...:.|:::.|:.. ::.|...|.:                   |..:|::.:..:||
Zfish   456 FETVMKLFPQIEEVMVQPLRE-SRDKYEELKQ-------------------IDDAMNEMQKKKTE 500

  Fly  1080 AKTTAAE 1086
            ..||..:
Zfish   501 NLTTGGK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde1c	NP_001137817.1	PDEase_I_N	662..722	CDD:462497	13/70 (19%)
		PDEase_I	807..1027	CDD:459723	72/225 (32%)
pde9aa	XP_009302928.2	None