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Protein Alignment Pde1c and pde5a

DIOPT Version :9

Sequence 1:	NP_001137817.1	Gene:	Pde1c / 34594	FlyBaseID:	FBgn0264815	Length:	1173	Species:	Drosophila melanogaster
Sequence 2:	XP_012821480.2	Gene:	pde5a / 780273	XenbaseID:	XB-GENE-479676	Length:	943	Species:	Xenopus tropicalis

Alignment Length:	300	Identity:	78/300 - (26%)
Similarity:	138/300 - (46%)	Gaps:	17/300 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   721 DRMYRRVSSSALTAFPPDVVRLLKNLDDWTFDVFALTEAASGQVVKYVAYELFNRYGSIHKFKIA 785
            :.|..:|::.|:.   |....|  .|.::.|..|.|::..:    ......:|.....:..|::.
Frog   600 ETMELQVTAGAIV---PSAQSL--KLTEFYFSDFELSDMET----TLATSRMFTDLNLVQTFQMK 655

  Fly   786 PGILEAFLHRVEEGYCRYRNPYHNNLHAVDVMQTIHYCLCNTGLMNWLTDLEIFASLLAALLHDY 850
            ...|..::..|::.| |....|||..||.:..|.:...|....:...|.||||.|.::|.|.||.
Frog   656 YETLCRWILSVKKNY-RKNVAYHNWRHAFNTAQCMFAALRTGKIQGKLNDLEILALMIATLSHDL 719

  Fly   851 EHTGTTNNFHVMSGSETALLYNDRAVLENHHASASFRLLREDEYNILSHLSREEFRELRGLVIEM 915
            :|.|..|:|...|....|.|| ..:::||||......:|......|||.||.::::.:..::.:.
Frog   720 DHRGVNNSFIQRSEHPLAQLY-CHSIMENHHFDQCLMILNSQGNQILSGLSVQDYKTVLKMIKQA 783

  Fly   916 VLGTDMTNHFQQMKAMRQLLTLQEATID----KQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLE 976
            :|.||:..:.::.....:|:..::...|    |:..|::::..||:|...|.|.|..|...|:..
Frog   784 ILATDLALYIKRRSDFFELVNKKKFKWDDPSQKELFLAMLMTACDLSAITKPWPVQQRIAELVAS 848

  Fly   977 EFFRQGDLE-KELGL-PFSPLCDRNNTLVAESQICFIDFI 1014
            ||:.|||.| :||.: |...:.......:...|:.|||.:
Frog   849 EFYDQGDKERRELNIEPIDLMNREKKDKIPSMQVGFIDAV 888

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.