Protein Alignment Pde1c and pde1ca

DIOPT Version :10

• Sequence 1: NP_001137817.1
• Gene: Pde1c / 34594
• FlyBaseID: FBgn0264815
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: XP_073797052.1
• Gene: pde1ca / 101883995
• ZFINID: ZDB-GENE-111215-4
• Length: 777
• Species: Danio rerio
• Alignment Length: 752
• Identity: 283/752 - (37%)
• Similarity: 387/752 - (51%)
• Gaps: 209/752 - (27%)

  Fly   421 ESLPPVDTPDALNKAAGRIRSLLRRMDHETVAYEDMQRNLHYAARVLEAVFIDESREGCNGNCKN 485
            :.||.||:|||:.|.|.|:|.|:::::....:..|:::||.|||.|||:|:|:|:|
Zfish    86 DDLPTVDSPDAMEKTAIRLRCLVKQLERGEASVVDLKKNLEYAASVLESVYIEETR--------- 141

  Fly   486 LNCSRHSHGRDDQQQDNNNSNRSCSLQEASPGGAGAGVTPGADNQDSIESRTKGVSQAPQTHSGP 550
                                                                             
Zfish   142 ----------------------------------------------------------------- 141

  Fly   551 TGPPSNTSSETIAQPAPKLQPALETVRESVMEESPSKDPGDKGPPPPASTSTLTSQTTTSSSATA 615
                                                                             
Zfish   142 ----------------------------------------------------------------- 141

  Fly   616 EPSAKAAESQAGSAGSSGSCSNPAAVHRQRRLRTPTWARSMSTNKTRLADEDDELSEVQPDAVPP 680
                                                          ||.|.:||||::|.|:||.
Zfish   142 ----------------------------------------------RLVDTEDELSDIQSDSVPS 160

  Fly   681 EVREWLASTFTRQMATSRRKSDEKPKFRSVAHAIRAGIFVDRMYRRVSSSALTAFPPDVVRLLKN 745
            |||:||||||||||....|:|:|||:|||:.||::|||||:|||||.|:....::||.|:..||:
Zfish   161 EVRDWLASTFTRQMGLMLRRSEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPSVITALKH 225

  Fly   746 LDDWTFDVFALTEAASGQVVKYVAYELFNRYGSIHKFKIAPGILEAFLHRVEEGYCRYRNPYHNN 810
            :|.|:||||.|.:|:....:|::.|||..||..|::|||....|.:|:..:|.||.::||||||.
Zfish   226 VDTWSFDVFTLNDASGDHSLKFIFYELLTRYDLINRFKIPVSALVSFVEALEVGYGKHRNPYHNL 290

  Fly   811 LHAVDVMQTIHYCLCNTGLMNWLTDLEIFASLLAALLHDYEHTGTTNNFHVMSGSETALLYNDRA 875
            :||.||.||:||.|..||:::|||:|||||.|.||.:|||||||||||||:.:.|:||:||||||
Zfish   291 IHAADVTQTVHYLLLKTGMVHWLTELEIFAMLFAAAVHDYEHTGTTNNFHIQTRSDTAILYNDRA 355

  Fly   876 VLENHHASASFRLLRE-DEYNILSHLSREEFRELRGLVIEMVLGTDMTNHFQQMKAMRQLLTLQE 939
            |.||||.||::|||:| ||.|||.:||::::||||.||:||||.|||:.||||:|||:..|...|
Zfish   356 VQENHHVSAAYRLLQEDDEMNILYNLSKDDWRELRTLVVEMVLATDMSCHFQQIKAMKNFLQQPE 420

  Fly   940 ATIDKQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLEEFFRQGDLEKELGLPFSPLCDRNNTLVA 1004
            . |||.|.|||:||..|||||||.|.:|:|||..||||||||||.|.||||||||||||.:|:||
Zfish   421 G-IDKPKALSLLLHTADISHPAKNWNMHYRWTTSLLEEFFRQGDKEAELGLPFSPLCDRKSTMVA 484

  Fly  1005 ESQICFIDFIVEPSMGVMSDMLELILAPIAPMNKSKPATLVEHETTANSTTNSAIVIPNSGITPS 1069
            :|||.||||||||:..|::||:|.|:.|:  :.::.||.|....   .|:.|:   ||:.|
Zfish   485 QSQIGFIDFIVEPTFTVLTDMIEKIMTPL--IEEASPAGLAGFR---RSSLNN---IPSDG---- 537

  Fly  1070 MDKPRDHRTEAKTTAAE--CLARKSVTGTTASKFNIPKPWLTCLVENKRIWKEQAVKDAEARALA 1132
                  .|:..::|.:|  .....|:.......|.  ..|...:.:|:..||.||.||.|.:|..
Zfish   538 ------KRSSVRSTGSEGGTSVNSSINAVDFKTFK--STWNEEVHKNREKWKAQAAKDLEEKAKQ 594

  Fly  1133 TAAEEAAAAAAAEAEESKPETETADGEQSEPAAEPAD 1169
            ...||.......:.:.|...|:|.|...::..|:..|
Zfish   595 EEMEENEKKKDTDTQSSDDNTKTEDKINTDSNAKSPD 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde1c	NP_001137817.1	PDEase_I_N	662..722	CDD:462497	39/59 (66%)
		PDEase_I	807..1027	CDD:459723	148/220 (67%)
pde1ca	XP_073797052.1	None