Protein Alignment Pde1c and pde1cb

DIOPT Version :9

• Sequence 1: NP_001137817.1
• Gene: Pde1c / 34594
• FlyBaseID: FBgn0264815
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: XP_017207862.1
• Gene: pde1cb / 100536162
• ZFINID: ZDB-GENE-090902-2
• Length: 698
• Species: Danio rerio
• Alignment Length: 912
• Identity: 303/912 - (33%)
• Similarity: 425/912 - (46%)
• Gaps: 282/912 - (30%)

  Fly   313 GSASAGDSRSSN---------QGPSNSGPAASAAVKMQPSSPNATNYLADNIQISS-ANLSQTEM 367
            ||.::..:||.|         |...:..|....||:.:.:|..:   ||.....|| ||..||..
Zfish     2 GSVTSAFTRSRNTLVKVGSEPQKEPDGKPRTGTAVRAKHTSRQS---LAQKTTGSSRANTPQTAT 63

  Fly   368 VVGRD-------------SADYTAM-HSINVGVGNSFL-RGDTDIPQESGHSFETPSNMSFTAGQ 417
            |...|             |...:|: :::..|...... :...|:|.:.....|..:
Zfish    64 VANEDGETNSRPLARFARSKSQSALWNTLTAGTSKKEKGKAQRDVPDDPQRIEEILA-------- 120

  Fly   418 WDTESLPPVDTPDALNKAAGRIRSLLRRMDHETVAYEDMQRNLHYAARVLEAVFIDESREGCNGN 482
               :.||..|||:|..|.|.|:|.|:::::....:..|:::||.|||.|||:|:|:|:|
Zfish   121 ---DELPSTDTPEATEKTAVRLRCLVKQLERGEASLVDLKKNLEYAATVLESVYIEETR------ 176

  Fly   483 CKNLNCSRHSHGRDDQQQDNNNSNRSCSLQEASPGGAGAGVTPGADNQDSIESRTKGVSQAPQTH 547
                                                                             
Zfish   177 ----------------------------------------------------------------- 176

  Fly   548 SGPTGPPSNTSSETIAQPAPKLQPALETVRESVMEESPSKDPGDKGPPPPASTSTLTSQTTTSSS 612
                                                                             
Zfish   177 ----------------------------------------------------------------- 176

  Fly   613 ATAEPSAKAAESQAGSAGSSGSCSNPAAVHRQRRLRTPTWARSMSTNKTRLADEDDELSEVQPDA 677
                                                             ||.|.:||||::|.|:
Zfish   177 -------------------------------------------------RLVDTEDELSDIQSDS 192

  Fly   678 VPPEVREWLASTFTRQMATSRRKSDEKPKFRSVAHAIRAGIFVDRMYRRVSSSALTAFPPDVVRL 742
            ||.|||:||||||||||....|:::|||:|||:.||::|||||:|||||.|:....::||:|:.:
Zfish   193 VPSEVRDWLASTFTRQMGLMLRRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPNVIAV 257

  Fly   743 LKNLDDWTFDVFALTEAASGQVVKYVAYELFNRYGSIHKFKIAPGILEAFLHRVEEGYCRYRNPY 807
            |||:|.|:||||||.|::....:|::.|||..||..|.:|||....|.:|:..:|.||.:|:|||
Zfish   258 LKNVDRWSFDVFALNESSGDHALKFIFYELLTRYDLISRFKIPVSALVSFVEALEVGYSKYKNPY 322

  Fly   808 HNNLHAVDVMQTIHYCLCNTGLMNWLTDLEIFASLLAALLHDYEHTGTTNNFHVMSGSETALLYN 872
            ||.:||.||.||:||.|..||:::|:|:|||||.:.||.:|||||||||||||:.:.|:.|:|||
Zfish   323 HNLIHAADVTQTVHYLLLKTGMVHWMTELEIFAMIFAAAIHDYEHTGTTNNFHIQTRSDAAILYN 387

  Fly   873 DRAVLENHHASASFRLLR-EDEYNILSHLSREEFRELRGLVIEMVLGTDMTNHFQQMKAMRQLLT 936
            ||:|||:||.|||:|||: :||.|||.:||::::||.|.||:||||.|||:.||||:|||:..|.
Zfish   388 DRSVLESHHVSASYRLLQDDDEMNILYNLSKDDWREFRALVVEMVLATDMSCHFQQVKAMKNYLQ 452

  Fly   937 LQEATIDKQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLEEFFRQGDLEKELGLPFSPLCDRNNT 1001
            ..|. |||.|.:||:||..|||||||.|.:|||||..||||||.|||.|.||||||||||||.:|
Zfish   453 QPEG-IDKPKAISLLLHAADISHPAKTWDLHHRWTTSLLEEFFLQGDKEAELGLPFSPLCDRKST 516

  Fly  1002 LVAESQICFIDFIVEPSMGVMSDMLELILAPIAPMNKSKPATLVEHETTA-----NSTTNSAIVI 1061
            :||:|||.||||||.|:..|::||.|.|:.|           |:|..|::     .|.|...:
Zfish   517 MVAQSQIGFIDFIVVPTFTVLTDMTEKIVTP-----------LIEEATSSGLSGFRSITGGDV-- 568

  Fly  1062 PNSGITPSMDKPRDHRTEAKTTAAECLARKSVTGTTASKFNIPKPWLTCLVENKRIWKEQAVKDA 1126
                          .|:...::|::..:..:.:..|....|....|...:..|:..||.||.|:.
Zfish   569 --------------KRSSVNSSASDSSSSHNGSLLTVDLKNFKALWNEEVSLNRERWKMQAAKET 619

  Fly  1127 EARA---LATAAEEAAAAAAAEAEESKPETETAD---------------------GEQSEPAAEP 1167
            |.:|   |....|........|.|.|:|:.:..:                     ||.||.|..|
Zfish   620 EEKAKRELEEQQEVENQVQKKELELSEPKKDDPEPGVVNGPPEESPHGKSKKLQNGEVSEEAESP 684

  Fly  1168 AD 1169
            ||
Zfish   685 AD 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde1c	NP_001137817.1	PDEase_I_N	666..722	CDD:285672	35/55 (64%)
		PDEase_I	807..1026	CDD:278654	140/219 (64%)
pde1cb	XP_017207862.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	300	1.000	Domainoid score	I1397
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	522	1.000	Inparanoid score	I1218
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D439875at33208
OrthoFinder	1	1.000	-	-		FOG0001902
OrthoInspector	1	1.000	-	-		otm25613
orthoMCL	1	0.900	-	-		OOG6_100946
Panther	1	1.100	-	-	O	PTHR11347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X171
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.970