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Protein Alignment crol and ZNF594

DIOPT Version :9

Sequence 1:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_115919.1	Gene:	ZNF594 / 84622	HGNCID:	29392	Length:	807	Species:	Homo sapiens

Alignment Length:	536	Identity:	201/536 - (37%)
Similarity:	286/536 - (53%)	Gaps:	36/536 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 IATGT--HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFT 278
            |.||.  :||:.|||.......||:|:|.|:.:||::|..||:.|..|.:|.||.:||.||..:.
Human   148 IHTGNKPYVCNECGKDSNQSSNLIIHQRIHTGKKPYICHECGKDFNQSSNLVRHKQIHSGGNPYE 212

  Fly   279 CIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFT 343
            |..|...|..:::|..|.:.||..||:.|..|.|.|::...|..|.|.||||.|:.|..|.:.|:
Human   213 CKECGKAFKGSSNLVLHQRIHSRGKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYECYDCGQMFS 277

  Fly   344 RKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCG------------- 395
            :..|:|.|.|.||||.|.:|:.|:|:|.:..|...|...|:|:.|::|..||
Human   278 QSSHLVPHQRIHTGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSGRTAFLKHQ 342

  Fly   396 ------------KKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD 448
                        |.:::.|.|....|.|..|..:.|..||::|........|.:.||||.|:.|.
Human   343 RLHAGEKIEECEKTFSKDEELREEQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTHTGEKPYECK 407

  Fly   449 FCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRK 513
            .|.|||.:...||.|.|.|:||.|..||.|.|:|.....|:.|.|.||||.|::|:.|.|||:::
Human   408 ECGKTFNQSSDLLRHHRIHSGEKPCVCSKCGKSFRGSSDLIRHHRVHTGEKPYECSECGKAFSQR 472

  Fly   514 DHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRL 578
            .|:|.|.:.||||.|::||.|.|.|.|:..|..|.|.|:|:.|:.|..|.|.|..:.....|..|
Human   473 SHLVTHQKIHTGEKPYQCTECGKAFRRRSLLIQHRRIHSGEKPYECKECGKLFIWRTAFLKHQSL 537

  Fly   579 HTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFT 643
            |||:   |.| |:|||::.|.|....:.|.....:.||.|.:.|.....||.|.. .||.::|:.
Human   538 HTGE---KLE-CEKTFSQDEELRGEQKIHQEAKAYWCNQCGRAFQGSSDLIRHQV-THTREKPYE 597

  Fly   644 CETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCS 708
            |:.|||:|....:||.|.|.|:.    |:|:.|.||.|:|.....|:.|.|.|:||||:.|:.|.
Human   598 CKECGKTFNQSSDLLRHHRIHSG----EKPYVCNKCGKSFRGSSDLIKHHRIHTGEKPYECSECG 658

  Fly   709 KAFVERGNLKRHMKMN 724
            |||.:|.:|..|.|::
Human   659 KAFSQRSHLATHQKIH 674

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.