Protein Alignment crol and PGBD1

DIOPT Version :9

• Sequence 1: NP_001245993.1
• Gene: crol / 34592
• FlyBaseID: FBgn0020309
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001171672.1
• Gene: PGBD1 / 84547
• HGNCID: 19398
• Length: 809
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 65/403 - (16%)
• Similarity: 118/403 - (29%)
• Gaps: 145/403 - (35%)

  Fly   583 SPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETC 647
            |.|..|.|:..|       .|.....:..|            :|.|......||...||
Human    36 SSHTQEICRLRF-------RHFCYQEAHGP------------QEALAQLRELCHQWLRP------ 75

  Fly   648 GKSFPLKGNLLFHQRSHTKGQEME----------RPFACEKCPKNFICKGHLVSHMRSHSGEKPH 702
                          ..|||.|.||          .|...:.|.|.:..:          |||:
Human    76 --------------EMHTKEQIMELLVLEQFLTILPKELQPCVKTYPLE----------SGEE-- 114

  Fly   703 ACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTM 767
            |.|:........|:..:.                      |.|..| .|::.|::..:.
Human   115 AVTVLENLETGSGDTGQQ----------------------ASVYIQ-GQDMHPMVAEYQ------ 150

  Fly   768 HTIQQITAGAAGGAGAVQLTPGLV-------------PLVTSTLISHNAA-AQQQSQKQQAAAAA 818
                    |.:....::||.||:.             |...|..:.|.:| .|:::.:.:|....
Human   151 --------GVSLECQSLQLLPGITTLKCEPPQRPQGNPQEVSGPVPHGSAHLQEKNPRDKAVVPV 207

  Fly   819 AAQQQAAAAAAAQQQAAQQQAAA--AHQQHQQQVAAQHQQQAAVAAHQQQQQQLQQQQQLLQLSI 881
            ....::......:::.||..||.  :|....::....:..|..|.:.....:::..:.:|.:
Human   208 FNPVRSQTLVKTEEETAQAVAAEKWSHLSLTRRNLCGNSAQETVMSLSPMTEEIVTKDRLFK--- 269

  Fly   882 QQAAHHHQQEQHRQQQQQQHQQQQQQQHHQQQQQGHPQAPPPQQQQQPPPIALISDPSALARAAI 946
                        .:|:..:..:|..:...:..::..||.|             .|.|.|..|.
Human   270 ------------AKQETSEEMEQSGEASGKPNRECAPQIP-------------CSTPIATERT-- 307

  Fly   947 QLQHLPANVEQHP 959
             :.||....::||
Human   308 -VAHLNTLKDRHP 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		COG5048	300..723	CDD:227381	28/149 (19%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368
		C2H2 Zn finger	419..439	CDD:275368
		C2H2 Zn finger	447..467	CDD:275368
		C2H2 Zn finger	475..495	CDD:275368
		C2H2 Zn finger	503..523	CDD:275368
		C2H2 Zn finger	531..551	CDD:275368
		C2H2 Zn finger	559..579	CDD:275368
		C2H2 Zn finger	587..607	CDD:275368	4/19 (21%)
		C2H2 Zn finger	615..636	CDD:275368	2/20 (10%)
		C2H2 Zn finger	644..664	CDD:275368	0/19 (0%)
		C2H2 Zn finger	676..696	CDD:275368	2/19 (11%)
		C2H2 Zn finger	704..722	CDD:275368	2/17 (12%)
PGBD1	NP_001171672.1	SCAN	40..142	CDD:128708	30/175 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..199		5/28 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..297		4/25 (16%)
		DDE_Tnp_1_7	418..775	CDD:372752

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100