DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment crol and ZSCAN16

DIOPT Version :9

Sequence 1:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_001307484.1	Gene:	ZSCAN16 / 80345	HGNCID:	20813	Length:	348	Species:	Homo sapiens

Alignment Length:	127	Identity:	49/127 - (38%)
Similarity:	71/127 - (55%)	Gaps:	3/127 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   401 KEHLANHMRSHTNETP---FRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLN 462
            |:.:.|..||...:..   ::|:.||||||.....:.|...||||.|::||.|.|.|.::.||:.
Human   217 KDIIENEGRSEWQQRERRRYKCDECGKSFSHSSDLSKHRRTHTGEKPYKCDECGKAFIQRSHLIG 281

  Fly   463 HVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHT 524
            |.|.|||..|::|..|.|.|:.:..|:.|.|.||||.|::|..|.:.|.....::.|.|.||
Human   282 HHRVHTGVKPYKCKECGKDFSGRTGLIQHQRIHTGEKPYECDECGRPFRVSSALIRHQRIHT 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		COG5048	300..723	CDD:227381	49/127 (39%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368	3/9 (33%)
		C2H2 Zn finger	419..439	CDD:275368	8/19 (42%)
		C2H2 Zn finger	447..467	CDD:275368	9/19 (47%)
		C2H2 Zn finger	475..495	CDD:275368	7/19 (37%)
		C2H2 Zn finger	503..523	CDD:275368	5/19 (26%)
		C2H2 Zn finger	531..551	CDD:275368
		C2H2 Zn finger	559..579	CDD:275368
		C2H2 Zn finger	587..607	CDD:275368
		C2H2 Zn finger	615..636	CDD:275368
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..722	CDD:275368
ZSCAN16	NP_001307484.1	SCAN	37..148	CDD:128708
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	160..184
		COG5048	<183..323	CDD:227381	42/105 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	205..226		2/8 (25%)
		C2H2 Zn finger	238..258	CDD:275368	8/19 (42%)
		C2H2 Zn finger	266..286	CDD:275368	9/19 (47%)
		C2H2 Zn finger	294..314	CDD:275368	7/19 (37%)
		zf-C2H2	320..342	CDD:306579	5/21 (24%)
		C2H2 Zn finger	322..342	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010