DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment crol and ZNF232

DIOPT Version :9

Sequence 1:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_055334.2	Gene:	ZNF232 / 7775	HGNCID:	13026	Length:	444	Species:	Homo sapiens

Alignment Length:	162	Identity:	65/162 - (40%)
Similarity:	90/162 - (55%)	Gaps:	4/162 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 SRKEHFTNHILWH----TGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEH 487
            :::|.|...::.|    ||:..|.|..|.|||....||:.|.|.|:||.|::||.|.|||.:..:
Human   281 AQEESFRQMVVIHKEIPTGKKDHECSECGKTFIYNSHLVVHQRVHSGEKPYKCSDCGKTFKQSSN 345

  Fly   488 LVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHT 552
            |..|.|.||||.||:|..|.|||....|:|.|.|.|:||.|::|..|.|.|::..:|:.|.|.|:
Human   346 LGQHQRIHTGEKPFECNECGKAFRWGAHLVQHQRIHSGEKPYECNECGKAFSQSSYLSQHRRIHS 410

  Fly   553 GDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSP 584
            |:.|..|..|.|.:.....|..|.|:|....|
Human   411 GEKPFICKECGKAYGWCSELIRHRRVHARKEP 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		COG5048	300..723	CDD:227381	65/162 (40%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368
		C2H2 Zn finger	419..439	CDD:275368	2/11 (18%)
		C2H2 Zn finger	447..467	CDD:275368	9/19 (47%)
		C2H2 Zn finger	475..495	CDD:275368	9/19 (47%)
		C2H2 Zn finger	503..523	CDD:275368	9/19 (47%)
		C2H2 Zn finger	531..551	CDD:275368	7/19 (37%)
		C2H2 Zn finger	559..579	CDD:275368	6/19 (32%)
		C2H2 Zn finger	587..607	CDD:275368
		C2H2 Zn finger	615..636	CDD:275368
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..722	CDD:275368
ZNF232	NP_055334.2	SCAN	75..188	CDD:128708
		SCAN	75..162	CDD:280241
		COG5048	<303..409	CDD:227381	49/105 (47%)
		zf-C2H2	303..325	CDD:278523	10/21 (48%)
		C2H2 Zn finger	305..325	CDD:275368	9/19 (47%)
		zf-H2C2_2	317..342	CDD:290200	14/24 (58%)
		C2H2 Zn finger	333..353	CDD:275368	9/19 (47%)
		zf-H2C2_2	345..368	CDD:290200	12/22 (55%)
		C2H2 Zn finger	361..381	CDD:275368	9/19 (47%)
		zf-H2C2_2	373..398	CDD:290200	12/24 (50%)
		COG5048	385..>437	CDD:227381	17/51 (33%)
		C2H2 Zn finger	389..409	CDD:275368	7/19 (37%)
		zf-H2C2_2	401..424	CDD:290200	9/22 (41%)
		C2H2 Zn finger	417..437	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100