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Protein Alignment crol and ZNF91

DIOPT Version :9

Sequence 1:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_003421.2	Gene:	ZNF91 / 7644	HGNCID:	13166	Length:	1191	Species:	Homo sapiens

Alignment Length:	602	Identity:	213/602 - (35%)
Similarity:	294/602 - (48%)	Gaps:	58/602 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 IATG--THVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFT 278
            |.||  ::.|:.|||.|.:...|..|:|.|:..||:.|:.||:.|:.|..|.:|.:||.|...:.
Human   595 IHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYK 659

  Fly   279 CIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFT 343
            |..|...|:|:::|..|...|:.:||:.|..|.|||.|...|..|...|.||..::|:.|.|.|.
Human   660 CKECGKAFSNSSTLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFN 724

  Fly   344 RKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHM 408
            |..::..|...||||.|::|:.|.|:|........|...||.:.|.:|..|||.:.....|..|.
Human   725 RSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHK 789

  Fly   409 RSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPH 473
            |.||.|.|::||.|||:|||....|.|...||||.|::|..|.|.|.....|..|...|.||..:
Human   790 RIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLY 854

  Fly   474 RCSYCMKTFTRKEH----------------------------LVNHIRQHTGETPFKCTYCTKAF 510
            :|..|.|.|.:..:                            |..|.|.||.|..:||..|.|||
Human   855 KCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAF 919

  Fly   511 TRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNH 575
            ::..|:..|.|.||||.|:||..|.|.|::...||.|...|||:.|::|..|.|.|.:...||.|
Human   920 SQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEH 984

  Fly   576 VRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDR 640
            ..:|||:.|:|||.|.|.|::...|..|.|.|:.:.|:.|..|.|.|.|...|..| ...|||::
Human   985 KIIHTGEKPYKCEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTH-KIIHTGEK 1048

  Fly   641 PFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACT 705
            |:.||.|||:|.....|..|:|.||:    |:|:.||:|.|.|.....|..|.|.|:||||:.|.
Human  1049 PYKCEECGKAFISSSTLNGHKRIHTR----EKPYKCEECGKAFSQSSTLTRHKRLHTGEKPYKCG 1109

  Fly   706 LCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAG-------VLTQVKQEVKPIIIPHHSA 763
            .|.|||.|...|.:| |:.|...       .|:.....|       :||..|:        .|:.
Human  1110 ECGKAFKESSALTKH-KIIHTGE-------KPYKCEKCGKAFNQSSILTNHKK--------IHTI 1158

  Fly   764 TTTMHTIQQITAGAAGG 780
            |..:..:.:..||.:.|
Human  1159 TPVIPLLWEAEAGGSRG 1175

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.