DRSC/TRiP Functional Genomics Resources

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Protein Alignment crol and ZNF75D

DIOPT Version :9

Sequence 1:NP_001245993.1 Gene:crol / 34592 FlyBaseID:FBgn0020309 Length:962 Species:Drosophila melanogaster
Sequence 2:NP_009062.2 Gene:ZNF75D / 7626 HGNCID:13145 Length:510 Species:Homo sapiens


Alignment Length:178 Identity:66/178 - (37%)
Similarity:89/178 - (50%) Gaps:13/178 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   294 RHMKRHSTDKPFACTICQKTFARKEHL----DNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK 354
            |...|....||..|         |:.|    |.|.:..|||.||:||.|.|:|.....::.|.|.
Human   331 RAFPRKKRKKPAT
C---------KQELPKLMDLHGKGPTGEKPFKCQECGKSFRVSSDLIKHHRI 386

  Fly   355 HTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRC 419
            ||||.|::|..|.:.|........|:|.|.|..|::|..|||.::...:|..|.|.||.|.||:|
Human   387 HTGEKPYKCQQCDRRFRWSSDLNKHFMTHQGIKPYRCSWCGKSFSHNTNLHTHQRIHTGEKPFKC 451

  Fly   420 EICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQH 467
            :.|||.|.:..|...|...||||.|:.|..|.:.|:|:..||.|.:.|
Human   452 DECGKRFIQNSHLIKHQRTHTGEQPYTCSLCKRNFSRRSSLLRHQKLH 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crolNP_001245993.1 C2H2 Zn finger 223..243 CDD:275368
C2H2 Zn finger 251..271 CDD:275368
C2H2 Zn finger 279..299 CDD:275368 1/4 (25%)
COG5048 300..723 CDD:227381 64/172 (37%)
C2H2 Zn finger 307..327 CDD:275368 5/23 (22%)
C2H2 Zn finger 335..355 CDD:275368 7/19 (37%)
C2H2 Zn finger 363..383 CDD:275368 5/19 (26%)
C2H2 Zn finger 391..411 CDD:275368 7/19 (37%)
C2H2 Zn finger 419..439 CDD:275368 7/19 (37%)
C2H2 Zn finger 447..467 CDD:275368 7/19 (37%)
C2H2 Zn finger 475..495 CDD:275368
C2H2 Zn finger 503..523 CDD:275368
C2H2 Zn finger 531..551 CDD:275368
C2H2 Zn finger 559..579 CDD:275368
C2H2 Zn finger 587..607 CDD:275368
C2H2 Zn finger 615..636 CDD:275368
C2H2 Zn finger 644..664 CDD:275368
C2H2 Zn finger 676..696 CDD:275368
C2H2 Zn finger 704..722 CDD:275368
ZNF75DNP_009062.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35
SCAN 45..133 CDD:307924
KRAB 234..275 CDD:307490
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 313..343 4/11 (36%)
zf-C2H2 365..387 CDD:306579 8/21 (38%)
C2H2 Zn finger 367..387 CDD:275368 7/19 (37%)
COG5048 <378..>492 CDD:227381 43/113 (38%)
C2H2 Zn finger 395..415 CDD:275368 5/19 (26%)
C2H2 Zn finger 423..443 CDD:275368 7/19 (37%)
C2H2 Zn finger 451..471 CDD:275368 7/19 (37%)
C2H2 Zn finger 479..499 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR23226
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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