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Protein Alignment crol and ZNF43

DIOPT Version :9

Sequence 1:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_001243582.1	Gene:	ZNF43 / 7594	HGNCID:	13109	Length:	818	Species:	Homo sapiens

Alignment Length:	525	Identity:	200/525 - (38%)
Similarity:	282/525 - (53%)	Gaps:	13/525 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 IATGT--HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFT 278
            |.||.  :.|..|.|.|.....|..|::.|...||:.|:.||:.|.....||:|.:||.|...:|
Human   288 IRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYT 352

  Fly   279 CIVC---FNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAK 340
            |..|   ||.|:|.|:   |.:.|:.:|.:.||.|.:.|:|..:|..|.:.||.:.|::|:.|.|
Human   353 CEECGKAFNQFSNLTT---HKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGK 414

  Fly   341 TFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLA 405
            .|.....:..|...||||.|::|:.|.|:|........|...|||:.|::|:||||.:.:..:|.
Human   415 AFKWSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLT 479

  Fly   406 NHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGE 470
            .|.|.||.|.|::||.|||:|||..:.|.|...|..:.|::|:.|.|.|.....|..|...||||
Human   480 THKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGE 544

  Fly   471 SPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCT 535
            .|::|..|.|.|.....|..|.|.||||.|:||..|.||||:..::..|.:.||||..:||..|.
Human   545 KPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECG 609

  Fly   536 KTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHL 600
            |.||:..:||.|.:.|||..|::|..|.|.|.:...||.|..:||.:.|:|||.|.|.|.....|
Human   610 KAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTL 674

  Fly   601 NNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHT 665
            ..|...|:.:.|:.|..|.|.|.....|..| ...|||::|:.||.|||:|....||:.|::.||
Human   675 TKHKIIHTGEKPYKCEECGKAFKLSSTLSTH-KIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIHT 738

  Fly   666 KGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMM 730
            .    |:|:.||:|.|.|....||.:|.|.|:.|:|:.|..|.|||.:..||..|.|::..:.:.
Human   739 G----EQPYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLY 799

  Fly   731 PPPPV 735
            .|..|
Human   800 KPEDV 804

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.