DRSC/TRiP Functional Genomics Resources

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Protein Alignment crol and ZNF24

DIOPT Version :9

Sequence 1:NP_001245993.1 Gene:crol / 34592 FlyBaseID:FBgn0020309 Length:962 Species:Drosophila melanogaster
Sequence 2:NP_001362744.1 Gene:ZNF24 / 7572 HGNCID:13032 Length:368 Species:Homo sapiens


Alignment Length:199 Identity:67/199 - (33%)
Similarity:98/199 - (49%) Gaps:29/199 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   374 EHYVNHYMWHTGQTPHQCDVCGK----KYTRKEHLANHMRSHTNETP----------FRC-EIC- 422
            |:.:....|......| ||..|:    ....|:.|.:.:.||  |.|          |:. |.| 
Human   173 ENQLKWASWELHSLRH-CDDDGRTENGALAPKQELPSALESH--EVPGTLNMGVPQIFKYGETCF 234

  Fly   423 --GKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRK 485
              |: |.||.:       .:.:..|.||.|.|.|::...|:.|.|.|:||.|:.|..|.|.|:|.
Human   235 PKGR-FERKRN-------PSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRS 291

  Fly   486 EHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ 550
            ..||.|.|.||||.|:||..|.|||::...::||.|.||||.|::|..|.|::::..:|..|.|:
Human   292 SILVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRR 356

  Fly   551 HTGD 554
            |..:
Human   357 HNAE 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crolNP_001245993.1 C2H2 Zn finger 223..243 CDD:275368
C2H2 Zn finger 251..271 CDD:275368
C2H2 Zn finger 279..299 CDD:275368
COG5048 300..723 CDD:227381 67/199 (34%)
C2H2 Zn finger 307..327 CDD:275368
C2H2 Zn finger 335..355 CDD:275368
C2H2 Zn finger 363..383 CDD:275368 1/8 (13%)
C2H2 Zn finger 391..411 CDD:275368 5/23 (22%)
C2H2 Zn finger 419..439 CDD:275368 6/23 (26%)
C2H2 Zn finger 447..467 CDD:275368 8/19 (42%)
C2H2 Zn finger 475..495 CDD:275368 9/19 (47%)
C2H2 Zn finger 503..523 CDD:275368 8/19 (42%)
C2H2 Zn finger 531..551 CDD:275368 6/19 (32%)
C2H2 Zn finger 559..579 CDD:275368
C2H2 Zn finger 587..607 CDD:275368
C2H2 Zn finger 615..636 CDD:275368
C2H2 Zn finger 644..664 CDD:275368
C2H2 Zn finger 676..696 CDD:275368
C2H2 Zn finger 704..722 CDD:275368
ZNF24NP_001362744.1 SCAN 48..160 CDD:128708
COG5048 <249..329 CDD:227381 36/79 (46%)
Necessary and sufficient for nuclear localization 251..301 22/49 (45%)
C2H2 Zn finger 253..273 CDD:275368 8/19 (42%)
C2H2 Zn finger 281..301 CDD:275368 9/19 (47%)
COG5048 305..>358 CDD:227381 21/52 (40%)
C2H2 Zn finger 309..329 CDD:275368 8/19 (42%)
C2H2 Zn finger 337..357 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23226
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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