DRSC/TRiP Functional Genomics Resources

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Protein Alignment crol and MAZ

DIOPT Version :9

Sequence 1:NP_001245993.1 Gene:crol / 34592 FlyBaseID:FBgn0020309 Length:962 Species:Drosophila melanogaster
Sequence 2:NP_001036004.1 Gene:MAZ / 4150 HGNCID:6914 Length:493 Species:Homo sapiens


Alignment Length:415 Identity:114/415 - (27%)
Similarity:169/415 - (40%) Gaps:99/415 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    87 QLPPPPPLPPQVTSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAGGGLPPATSGNG- 150
            |.|.|||.||.|::.||.||..|:||:...||..||:|..:..|.|..|::    |...|...| 
Human   129 QPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAPTSTVAVAPVASA----LEKKTKSKGP 189

  Fly   151 ------------GQQVTVTTTSSSTSSGGSTTSGG----TTTTAGELLMPKMEGGIHGVDGSGNG 199
                        |..:.......:.:..|...||.    |......|.:|::.|   ...|.|..
Human   190 YICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSG---AGGGGGEA 251

  Fly   200 GNGGGQNVALAPDG--TPIATG-----THVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQG 257
            |.|||. .|:|..|  |..|:|     .|.|::|||.|:..|.                      
Human   252 GAGGGA-AAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYH---------------------- 293

  Fly   258 FTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDN 322
                                              |.||...||.:||:.|.:||:.|.||:.:..
Human   294 ----------------------------------LNRHKLSHSDEKPYQCPVCQQRFKRKDRMSY 324

  Fly   323 HFRSHTG--ETPFRCQYCAKTFTRKEHMVNHVRK-HTGETPHRCDICKKSFTRKEHYVNHYMWHT 384
            |.|||.|  ..|:.|.:|.|:|:|.:|:.:|||: |:.|.|.:|:.|:.:|..|:....|.:.|.
Human   325 HVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHE 389

  Fly   385 GQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTG-ETPHR-- 446
            .:.|  |.||||..: ..::::||:.|:......||:|.|.|:...:...|.:...| :.|..  
Human   390 EKVP--CHVCGKMLS-SAYISDHMKVHSQGPHHVCELCNKGFTTAAYLRIHAVKDHGLQAPRADR 451

  Fly   447 --CDFCSKTFTRKEHLLNHVRQHTG 469
              |..||........|..|::.|.|
Human   452 ILCKLCSVHCKTPAQLAGHMQTHLG 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crolNP_001245993.1 C2H2 Zn finger 223..243 CDD:275368 6/19 (32%)
C2H2 Zn finger 251..271 CDD:275368 0/19 (0%)
C2H2 Zn finger 279..299 CDD:275368 3/19 (16%)
COG5048 300..723 CDD:227381 57/178 (32%)
C2H2 Zn finger 307..327 CDD:275368 8/19 (42%)
C2H2 Zn finger 335..355 CDD:275368 9/20 (45%)
C2H2 Zn finger 363..383 CDD:275368 5/19 (26%)
C2H2 Zn finger 391..411 CDD:275368 7/19 (37%)
C2H2 Zn finger 419..439 CDD:275368 6/19 (32%)
C2H2 Zn finger 447..467 CDD:275368 5/19 (26%)
C2H2 Zn finger 475..495 CDD:275368
C2H2 Zn finger 503..523 CDD:275368
C2H2 Zn finger 531..551 CDD:275368
C2H2 Zn finger 559..579 CDD:275368
C2H2 Zn finger 587..607 CDD:275368
C2H2 Zn finger 615..636 CDD:275368
C2H2 Zn finger 644..664 CDD:275368
C2H2 Zn finger 676..696 CDD:275368
C2H2 Zn finger 704..722 CDD:275368
MAZNP_001036004.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 59..78
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 121..146 9/16 (56%)
C2H2 Zn finger 192..212 CDD:275368 1/19 (5%)
C2H2 Zn finger 281..301 CDD:275368 9/75 (12%)
SFP1 <303..360 CDD:227516 23/56 (41%)
C2H2 Zn finger 309..329 CDD:275368 8/19 (42%)
C2H2 Zn finger 339..357 CDD:275368 7/17 (41%)
C2H2 Zn finger 368..388 CDD:275368 5/19 (26%)
C2H2 Zn finger 394..413 CDD:275368 7/19 (37%)
C2H2 Zn finger 421..437 CDD:275368 5/15 (33%)
C2H2 Zn finger 454..474 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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