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Protein Alignment crol and ZNF470

DIOPT Version :10

Sequence 1:	NP_477243.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_001001668.3	Gene:	ZNF470 / 388566	HGNCID:	22220	Length:	717	Species:	Homo sapiens

Alignment Length:	504	Identity:	198/504 - (39%)
Similarity:	285/504 - (56%)	Gaps:	6/504 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 HRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDK 303
            |::...|:|...|..|.:.|:....||.|.:||.|...:.||.|...|:.:..|.:|.:.|:.:|
Human   218 HKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIHTGEK 282

  Fly   304 PFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKK 368
            ||.||.|.|.|::..||..|.|.||||.|::|:.|.|.|::..|:..|.|.||||.|:.|..|.|
Human   283 PFECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQCNKAFSQLAHLAQHQRVHTGEKPYECIECGK 347

  Fly   369 SFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMR-SHTNETPFRCEICGKSFSRKEHF 432
            :|:......:|...|||:.|::|..|||.:.:...|..|.| .||.|.||.|..|||:|:.....
Human   348 AFSDCSSLAHHRRIHTGKRPYECIDCGKAFRQNASLIRHRRYYHTGEKPFDCIDCGKAFTDHIGL 412

  Fly   433 TNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTG 497
            ..|...||||.|::|:.|.|.|:....|..|.|.||||.|:.|:.|.|.|:.:..|..|.|.|||
Human   413 IQHKRTHTGERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTG 477

  Fly   498 ETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYC 562
            |.|::|..|.|||.:..|:.:|.|.||||.|::|..|:|||::..||..|.:.|||:.|:.|..|
Human   478 EKPYECKECGKAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECKEC 542

  Fly   563 KKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEH 627
            .|.|::..||..|.|:|||:.|::|..|.|.|:...:|..|.|.||...|:.|..|.|.|.::..
Human   543 GKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGSYLVQHQRLHSGKRPYECLECGKAFRQRAS 607

  Fly   628 LINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSH 692
            ||.| .|||||::|:.|..|||:|..:.:|..|||.||.    |:|:.|::|.|.|....||..|
Human   608 LICH-QRCHTGEKPYECNVCGKAFSHRKSLTLHQRIHTG----EKPYECKECSKAFSQVAHLTLH 667

  Fly   693 MRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQI 741
            .|.|:||:|:.|..|.|||.:..:|..|.:::..::.:......|:.|:
Human   668 KRIHTGERPYECKECGKAFRQSVHLAHHQRIHTGESSVILSSALPYHQV 716

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.