back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment crol and ZNF680

DIOPT Version :9

Sequence 1:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_848653.2	Gene:	ZNF680 / 340252	HGNCID:	26897	Length:	530	Species:	Homo sapiens

Alignment Length:	386	Identity:	145/386 - (37%)
Similarity:	211/386 - (54%)	Gaps:	5/386 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 RHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHR 362
            |.:..|.|.|....|.|.:..:.::|.:.:||:..|:|:.|.|:|....|:..|:|.||.|..::
Human   147 RTTQSKIFQCDKYVKVFHKFSNSNSHKKRNTGKKVFKCKECGKSFCMLSHLTQHIRIHTRENSYK 211

  Fly   363 CDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFS 427
            |:.|.|........:.|...|.|:.|::|:.|||.:.:...|..|.:.|..|.||:||.|||:||
Human   212 CEECGKVLNWFSELIKHKGIHMGEKPYKCEECGKAFNQSSTLIKHKKIHIEEKPFKCEECGKAFS 276

  Fly   428 RKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHI 492
            .....:.|.:.|||:.|::||.|.|.|.....|.||.|.||||.|.:|..|.|.|.:..:|..|.
Human   277 LFSILSKHKIIHTGDKPYKCDECHKAFNWFATLTNHKRIHTGEKPFKCEECGKDFNQFSNLTKHK 341

  Fly   493 RQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPH 557
            :.||||.|:||..|.|||.:..::..|.:.||||..:||..|.|.|.:..:||.|:|.|||:.|:
Human   342 KIHTGEKPYKCEECGKAFNQFANLTRHKKIHTGEKSYKCEECGKAFIQSSNLTEHMRIHTGEKPY 406

  Fly   558 RCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPF 622
            :|..|.|.|.....||.|.|:||.::.:|||.|.|.||....|.||...|:.:..:.|:.|...|
Human   407 KCEECGKAFNGCSSLTRHKRIHTRENTYKCEECGKGFTLFSTLTNHKVIHTGEKSYKCDECGNVF 471

  Fly   623 TRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNF 683
            .....|.|| .|.|..::|:.||.|||:|....:|..|::.|| |:::.:|   |||..||
Human   472 NWPATLANH-KRIHAREKPYKCEECGKAFNRSSHLTRHKKIHT-GEKLYKP---EKCDNNF 527

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.