Protein Alignment crol and Gm14325

DIOPT Version :10

• Sequence 1: NP_477243.1
• Gene: crol / 34592
• FlyBaseID: FBgn0020309
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001020020.2
• Gene: Gm14325 / 329575
• MGIID: 3702875
• Length: 498
• Species: Mus musculus
• Alignment Length: 445
• Identity: 174/445 - (39%)
• Similarity: 239/445 - (53%)
• Gaps: 5/445 - (1%)

  Fly   260 TSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHF 324
            ||:...||.:..........|.|...||..:..:||..:|:.:|...|..|.|.|.....|..|.
Mouse    58 TSRSHGRHERSCSAEQPSEFIQCGKAFAYESGRQRHQIKHTGEKHHDCNQCGKDFRTWNVLQIHK 122

  Fly   325 RSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPH 389
            |:||||.|:.|:.|.|.|.|..|:..|.|.|.||..:.|:.|.|:|.|:.....|...|||:.|:
Mouse   123 RTHTGEKPYDCKQCGKAFARSCHLRIHNRTHAGEKQYECNQCGKAFKRRSDLQIHKRTHTGEKPY 187

  Fly   390 QCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTF 454
            :|..|||.:.....|..|.|:||.|.|:.|:.|||:||:..|...|...||||.|:.|:.|.|.|
Mouse   188 ECKQCGKAFVSSGELQKHKRTHTGEKPYECKQCGKAFSQSSHLRIHKRTHTGEKPYECNQCGKAF 252

  Fly   455 TRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNH 519
            .|...|..|.|.||||.|:.|..|.|.|....||..|.|:|||:.|::|..|.|||.....:..|
Mouse   253 ARSGDLQKHKRTHTGEKPYECKQCGKAFAHSSHLHIHERRHTGDKPYECKQCGKAFAVFYTLQMH 317

  Fly   520 VRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSP 584
            .|.|||:.|::|..|.|.||....|..|.:.|||:.|:.|..|.|||::..||..|.|.|||:.|
Mouse   318 KRTHTGDKPYECKQCGKAFTVIYTLQMHKQTHTGEKPYECKQCGKTFSQSRHLRIHKRTHTGEKP 382

  Fly   585 HKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGK 649
            ::|..|.|.|.|......|.|.|:.:.|:.||.|.|.|.|:..|..| .|.|||::|:.|:.|||
Mouse   383 YECNQCGKAFARSGDQQEHKRTHTGEKPYECNQCGKAFIRRRVLQIH-KRTHTGEKPYECKQCGK 446

  Fly   650 SFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHAC 704
            :|....:|..|:|:|:.    |:|:.|::|.|.|....||..|.::|:||:|:.|
Mouse   447 AFASSSDLQKHKRTHSG----EKPYECKQCGKAFAQSSHLRIHKQTHTGERPYEC 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crol	NP_477243.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368	4/10 (40%)
		C2H2 Zn finger	279..299	CDD:275368	6/19 (32%)
		COG5048	300..723	CDD:227381	163/405 (40%)
		C2H2 Zn finger	307..327	CDD:275368	7/19 (37%)
		C2H2 Zn finger	335..355	CDD:275368	8/19 (42%)
		C2H2 Zn finger	363..383	CDD:275368	6/19 (32%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
		C2H2 Zn finger	419..439	CDD:275368	8/19 (42%)
		C2H2 Zn finger	447..467	CDD:275368	8/19 (42%)
		C2H2 Zn finger	475..495	CDD:275368	8/19 (42%)
		C2H2 Zn finger	503..523	CDD:275368	7/19 (37%)
		C2H2 Zn finger	531..551	CDD:275368	7/19 (37%)
		C2H2 Zn finger	559..579	CDD:275368	9/19 (47%)
		C2H2 Zn finger	587..607	CDD:275368	7/19 (37%)
		C2H2 Zn finger	615..636	CDD:275368	9/20 (45%)
		C2H2 Zn finger	644..664	CDD:275368	8/19 (42%)
		C2H2 Zn finger	676..696	CDD:275368	7/19 (37%)
		C2H2 Zn finger	704..722	CDD:275368	1/1 (100%)
Gm14325	NP_001020020.2	KRAB	3..44	CDD:460171
		C2H2 Zn finger	79..97	CDD:275368	5/17 (29%)
		C2H2 Zn finger	105..125	CDD:275368	7/19 (37%)
		COG5048	129..498	CDD:227381	151/374 (40%)
		C2H2 Zn finger	133..153	CDD:275368	8/19 (42%)
		C2H2 Zn finger	161..181	CDD:275368	6/19 (32%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
		C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		C2H2 Zn finger	357..377	CDD:275368	9/19 (47%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		C2H2 Zn finger	413..433	CDD:275368	9/20 (45%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)