Protein Alignment crol and Zfp729b

DIOPT Version :10

• Sequence 1: NP_477243.1
• Gene: crol / 34592
• FlyBaseID: FBgn0020309
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001388788.1
• Gene: Zfp729b / 100416706
• MGIID: 2145180
• Length: 1055
• Species: Mus musculus
• Alignment Length: 498
• Identity: 180/498 - (36%)
• Similarity: 262/498 - (52%)
• Gaps: 5/498 - (1%)

  Fly   223 CDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFA 287
            |::|||.|.:..:|..|.:.|:..||:.|:||.:.|.:...|::|.:||:|...:...:|.|.|.
Mouse   340 CEVCGKAFDYPSRLSTHAKMHTGEKPYKCEVCEKAFRSLSSLSKHRRIHMGDNYYNSELCSNAFV 404

  Fly   288 NNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHV 352
            ..:.|.:|.|....:||:.|.:|.|.|.....|..|...||||..::|:.|.|.|.....:..|.
Mouse   405 YPSRLSKHKKICRGEKPYKCEVCGKAFHVSSLLSKHRTIHTGEKLYKCEVCGKAFYYPSRLSTHK 469

  Fly   353 RKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPF 417
            |.||||.|::|::|.|:|........|...|||:.|::|..|||.:.....|:.|.:.||.|.|:
Mouse   470 RIHTGEKPYKCEVCGKAFCFPPSLSKHKRIHTGEKPYKCKECGKAFRFPSSLSAHKKIHTGEKPY 534

  Fly   418 RCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTF 482
            :||:|||:|......:.|.:.||||.|::||.|.:.|.....|.:|...||||.|::|..|.|.|
Mouse   535 KCEVCGKAFHYPSLLSKHKIIHTGEKPYKCDICDQAFHVPSKLSHHKIIHTGEKPYKCEVCGKAF 599

  Fly   483 TRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNH 547
            .....|..|...|||:.|:||..|.|||.....:.:|.:.||||.|:||..|.|.|.....|:.|
Mouse   600 HYSSLLSKHKIIHTGKKPYKCEVCDKAFHYPSRLFSHTKMHTGEKPYKCEVCGKAFCSPSSLSKH 664

  Fly   548 VRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNP 612
            .|.|..:..:.|..|.|||.....|:.|..:|||::.:..|.|.|.|.....|..|.:.:..:.|
Mouse   665 KRIHKVEKAYSCEICGKTFCIPLLLSKHKIIHTGENHYNSEVCSKFFVYPSRLPKHKKIYKREKP 729

  Fly   613 HCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACE 677
            :.|:||.|.|.....|..| .:.||.::|:.|:.|||:|.:...||.|:..||.    |:|:.||
Mouse   730 YNCDVCGKAFDYPSRLSKH-KKIHTREKPYKCDVCGKAFHIASLLLVHKGIHTG----EKPYKCE 789

  Fly   678 KCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRH 720
            .|.|.|.....|..|.|.|:||||:.|.:|.|||....:|.:|
Mouse   790 DCGKAFYYPSFLSKHKRIHTGEKPYQCEVCGKAFHVSSSLSKH 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crol	NP_477243.1	C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..299	CDD:275368	6/19 (32%)
		COG5048	300..723	CDD:227381	155/421 (37%)
		C2H2 Zn finger	307..327	CDD:275368	6/19 (32%)
		C2H2 Zn finger	335..355	CDD:275368	6/19 (32%)
		C2H2 Zn finger	363..383	CDD:275368	5/19 (26%)
		C2H2 Zn finger	391..411	CDD:275368	6/19 (32%)
		C2H2 Zn finger	419..439	CDD:275368	7/19 (37%)
		C2H2 Zn finger	447..467	CDD:275368	6/19 (32%)
		C2H2 Zn finger	475..495	CDD:275368	6/19 (32%)
		C2H2 Zn finger	503..523	CDD:275368	6/19 (32%)
		C2H2 Zn finger	531..551	CDD:275368	7/19 (37%)
		C2H2 Zn finger	559..579	CDD:275368	7/19 (37%)
		C2H2 Zn finger	587..607	CDD:275368	6/19 (32%)
		C2H2 Zn finger	615..636	CDD:275368	7/20 (35%)
		C2H2 Zn finger	644..664	CDD:275368	8/19 (42%)
		C2H2 Zn finger	676..696	CDD:275368	8/19 (42%)
		C2H2 Zn finger	704..722	CDD:275368	7/17 (41%)
Zfp729b	NP_001388788.1	KRAB	15..73	CDD:214630
		C2H2 Zn finger	88..136	CDD:275368
		SFP1	<96..207	CDD:227516
		C2H2 Zn finger	144..164	CDD:275368
		C2H2 Zn finger	172..192	CDD:275368
		C2H2 Zn finger	200..220	CDD:275368
		COG5048	224..653	CDD:227381	115/312 (37%)
		C2H2 Zn finger	228..248	CDD:275368
		C2H2 Zn finger	256..276	CDD:275368
		C2H2 Zn finger	284..304	CDD:275368
		C2H2 Zn finger	312..332	CDD:275368
		C2H2 Zn finger	340..360	CDD:275368	7/19 (37%)
		C2H2 Zn finger	368..388	CDD:275368	6/19 (32%)
		C2H2 Zn finger	424..444	CDD:275368	6/19 (32%)
		C2H2 Zn finger	452..472	CDD:275368	6/19 (32%)
		COG5048	476..889	CDD:227381	133/362 (37%)
		C2H2 Zn finger	480..500	CDD:275368	5/19 (26%)
		C2H2 Zn finger	508..528	CDD:275368	6/19 (32%)
		C2H2 Zn finger	536..556	CDD:275368	7/19 (37%)
		C2H2 Zn finger	564..584	CDD:275368	6/19 (32%)
		C2H2 Zn finger	592..612	CDD:275368	6/19 (32%)
		C2H2 Zn finger	620..640	CDD:275368	6/19 (32%)
		C2H2 Zn finger	648..668	CDD:275368	7/19 (37%)
		C2H2 Zn finger	676..696	CDD:275368	7/19 (37%)
		C2H2 Zn finger	705..724	CDD:275368	6/18 (33%)
		C2H2 Zn finger	732..752	CDD:275368	7/20 (35%)
		C2H2 Zn finger	760..780	CDD:275368	8/19 (42%)
		C2H2 Zn finger	788..808	CDD:275368	8/19 (42%)
		C2H2 Zn finger	816..836	CDD:275368	7/17 (41%)
		C2H2 Zn finger	844..864	CDD:275368
		C2H2 Zn finger	872..892	CDD:275368
		C2H2 Zn finger	900..920	CDD:275368
		C2H2 Zn finger	928..948	CDD:275368
		SFP1	<950..1029	CDD:227516
		C2H2 Zn finger	956..976	CDD:275368
		C2H2 Zn finger	984..1004	CDD:275368
		C2H2 Zn finger	1012..1032	CDD:275368