Protein Alignment crol and ZNF730

DIOPT Version :9

• Sequence 1: NP_001245993.1
• Gene: crol / 34592
• FlyBaseID: FBgn0020309
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: XP_016881603.1
• Gene: ZNF730 / 100129543
• HGNCID: 32470
• Length: 514
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 149/412 - (36%)
• Similarity: 207/412 - (50%)
• Gaps: 25/412 - (6%)

  Fly   226 CGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNT 290
            |..:.:|:    :|::.::..        .|..|||     |.||      |.|.....||...:
Human   128 CKNVDEFK----MHKKGYNRH--------NQCLTTS-----HSKI------FQCDKYVKVFHKFS 169

  Fly   291 SLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKH 355
            :..||..||::.|||.|..|.|.|....||..|.:.||||..::|:...|.|....:...| ::.
Human   170 NSNRHKIRHTSKKPFKCKECGKLFCILSHLAQHKKIHTGEKSYKCEEYGKAFNESSNCTTH-KRI 233

  Fly   356 TGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCE 420
            |.:.|::|..|.|:|....|:..|...|||:.|:||:.|||.:.:..:|..|.|.||.|.|::||
Human   234 TEKKPYKCKECGKAFNWFSHFTTHKRIHTGEKPYQCEKCGKFFNQSTNLTTHKRIHTGEKPYKCE 298

  Fly   421 ICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRK 485
            .|||:|::..:.|.|...||.|.|::|:.|.|.|.....|..|.|.|.||.|::|..|.|.|.|.
Human   299 ECGKAFNQSSNLTEHKKIHTKEQPYKCEKCGKAFKWSSTLTKHKRIHNGEKPYKCEECGKAFNRS 363

  Fly   486 EHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ 550
            ..|..|...|||..|:|...|.|||.:...:..|...||.|..:||..|.|.|:|..|||.|.|.
Human   364 STLNRHKITHTGGKPYKYKECGKAFNQSSTLTIHKIIHTVEKFYKCEECGKAFSRISHLTTHKRI 428

  Fly   551 HTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCC 615
            |||:.|::|..|.:.|.:...||.|.|:|||:.|::||.|.|.|.|...|..|...||.:..:.|
Human   429 HTGEKPYKCEECGRAFNQSSTLTTHKRIHTGEKPYECEECGKAFNRSSTLTTHKIIHSGEKIYKC 493

  Fly   616 NVCNKPFTRKEHLINHMSRCHT 637
            ..|.|.|.|..||..|.: .||
Human   494 KECGKAFRRFSHLTRHKT-IHT 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368	3/16 (19%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..299	CDD:275368	5/19 (26%)
		COG5048	300..723	CDD:227381	131/338 (39%)
		C2H2 Zn finger	307..327	CDD:275368	7/19 (37%)
		C2H2 Zn finger	335..355	CDD:275368	4/19 (21%)
		C2H2 Zn finger	363..383	CDD:275368	6/19 (32%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
		C2H2 Zn finger	419..439	CDD:275368	8/19 (42%)
		C2H2 Zn finger	447..467	CDD:275368	7/19 (37%)
		C2H2 Zn finger	475..495	CDD:275368	7/19 (37%)
		C2H2 Zn finger	503..523	CDD:275368	5/19 (26%)
		C2H2 Zn finger	531..551	CDD:275368	10/19 (53%)
		C2H2 Zn finger	559..579	CDD:275368	7/19 (37%)
		C2H2 Zn finger	587..607	CDD:275368	8/19 (42%)
		C2H2 Zn finger	615..636	CDD:275368	8/20 (40%)
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..722	CDD:275368
ZNF730	XP_016881603.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100020
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900