Protein Alignment Tsp33B and CD81

DIOPT Version :10

• Sequence 1: NP_523552.1
• Gene: Tsp33B / 34590
• FlyBaseID: FBgn0032376
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: XP_054226604.1
• Gene: CD81 / 975
• HGNCID: 1701
• Length: 335
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 48/224 - (21%)
• Similarity: 79/224 - (35%)
• Gaps: 72/224 - (32%)

  Fly    52 YLFGIYVF---GAQVVVTFLCSIAMWRRIWRRRCTPNIRLLLSVWAFYSCVIIASGFGC-----V 108
            :..|||:.   ||  |:.|:..:..:..|...:|      ||.  .|::|::|.  |.|     :
Human   157 FYVGIYILIAVGA--VMMFVGFLGCYGAIQESQC------LLG--TFFTCLVIL--FACEVAAGI 209

  Fly   109 WNLYRGVDVLENAA---DTSLTRGI---DMYYSCPEWKLLWDGLQWHKECCGVHGYKDWMNAEWM 167
            |.......:.::..   |.:|.:.:   |...:....|...:.|    :|||    ...:.|
Human   210 WGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETL----DCCG----SSTLTA--- 263

  Fly   168 PRRENNCTSMVLAPFACCKRSCDSCFNNFLPSEGQSIGGN-----SRQPFPALTVDSINANGCLP 227
                  .|:.||.             ||..|| |.:|..|     ..|....|....:...| :.
Human   264 ------LTTSVLK-------------NNLCPS-GSNIISNLFKEDCHQKIDDLFSGKLYLIG-IA 307

  Fly   228 AFVSAVWNCFYILMALWVLALKFLIVLCC 256
            |.|.||...|.:::::         ||||
Human   308 AIVVAVIMIFEMILSM---------VLCC 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp33B	NP_523552.1	CD151_like_LEL	112..237	CDD:239408	26/135 (19%)
CD81	XP_054226604.1	Tetraspanin	122..327	CDD:459767	46/222 (21%)