Protein Alignment Tsp33B and UPK1A

DIOPT Version :10

• Sequence 1: NP_523552.1
• Gene: Tsp33B / 34590
• FlyBaseID: FBgn0032376
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: XP_054175633.1
• Gene: UPK1A / 11045
• HGNCID: 12577
• Length: 313
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 55/204 - (26%)
• Similarity: 79/204 - (38%)
• Gaps: 50/204 - (24%)

  Fly    59 FGAQVVVTFLCSIAMWRRIWRRRCTPNIRLLLSVWAFYSCVIIASGFGCVWNLYRGVDVLENAAD 123
            |...:|.:|....|:.||  |......:.|:|.|:.|.....|.|        |...|.:  .::
Human    73 FSFFMVASFGVGAALCRR--RSMVLTYLVLMLIVYIFECASCITS--------YTHRDYM--VSN 125

  Fly   124 TSL-TRGIDMYYSC-----PEWKLLWDGLQWHKECCGVHGYKDWMNAEWMPRRENNCTSMVLAPF 182
            .|| |:.:..:||.     .|...|||.:...:||||..|..||:|.....|.   .|..|:.|:
Human   126 PSLITKQMLTFYSADTDQGQELTRLWDRVMIEQECCGTSGPMDWVNFTSAFRA---ATPEVVFPW 187

  Fly   183 --ACCKRSCDSCFNNFLP--SEGQSIGGNSRQPFPALTVDSINANGCLPAFVSAV--------WN 235
              .||:|:     .||:|  .||..:|          .:|.:...||......|:        |.
Human   188 PPLCCRRT-----GNFIPLNEEGCRLG----------HMDYLFTKGCFEHIGHAIDSYTWGISWF 237

  Fly   236 CFYILMALW 244
            .|.|||  |
Human   238 GFAILM--W 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp33B	NP_523552.1	CD151_like_LEL	112..237	CDD:239408	37/142 (26%)
UPK1A	XP_054175633.1	Tetraspanin	25..>163	CDD:459767	27/101 (27%)
		uroplakin_I_like_LEL	113..231	CDD:239409	38/145 (26%)