Protein Alignment Tsp33B and TSPAN5

DIOPT Version :10

• Sequence 1: NP_523552.1
• Gene: Tsp33B / 34590
• FlyBaseID: FBgn0032376
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 59/270 - (21%)
• Similarity: 102/270 - (37%)
• Gaps: 84/270 - (31%)

  Fly    43 DIECRLVYGYLFGIYVFGAQVV-----VTFLCSIAMWRRIWRRR-CTPNIRLLLS------VWAF 95
            ::.|.:.|      ::||..|:     :||| .|.:|  .|..: ...||..:..      ||.|
Human    10 EVSCCIKY------FIFGFNVIFWFLGITFL-GIGLW--AWNEKGVLSNISSITDLGGFDPVWLF 65

  Fly    96 --YSCVIIASGF-GCV------------WNLYRGV----------------DVLENAADTSLTRG 129
              ...|:...|| ||:            ::::.|:                |.:::.....:...
Human    66 LVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNN 130

  Fly   130 IDMYYSCPEWKLLWDGLQWHKECCGVHGYKDW-MNAEWMPRRENNCTSMVLA------PFACCKR 187
            |..|....:.:.|.|..|.:.:|||..|..|| :|..:      |||....:      ||:||.:
Human   131 IRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYF------NCTDSNASRERCGVPFSCCTK 189

  Fly   188 SCDSCFNNFLPSE---GQSIGGNSRQPFPALTVDS---INANGCLPAFVSAVWNCFYILMALWV- 245
            .         |:|   ....|.::||. |  .||.   |...||:|.|...:.:...|:..:::
Human   190 D---------PAEDVINTQCGYDARQK-P--EVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIG 242

  Fly   246 LALKFLIVLC 255
            :||..:..:|
Human   243 IALLQIFGIC 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp33B	NP_523552.1	CD151_like_LEL	112..237	CDD:239408	34/153 (22%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	58/265 (22%)
		TM4SF9_like_LEL	113..233	CDD:239412	33/137 (24%)