Protein Alignment Vha100-5 and atp6v0a1b

DIOPT Version :10

• Sequence 1: NP_609515.1
• Gene: Vha100-5 / 34587
• FlyBaseID: FBgn0032373
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_009295518.1
• Gene: atp6v0a1b / 553691
• ZFINID: ZDB-GENE-050522-215
• Length: 868
• Species: Danio rerio
• Alignment Length: 885
• Identity: 416/885 - (47%)
• Similarity: 582/885 - (65%)
• Gaps: 88/885 - (9%)

  Fly     1 MGDMFRSEKMALCQLFIQPEAAYASIAELGEKGCVQFRDLNEEVSAFQRKYVNEVRRCDDMERRL 65
            ||::||||:|.|.|||:|.||||..::||||.|.|||||||.:|:.||||:|||||||::|:|:|
Zfish     1 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGMVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKL 65

  Fly    66 RYVESEMKKDEVKLPVLRPEEEPIAPNPREIVDLEAQLEKTDNELREMSANGASLDANFRHMQEL 130
            |:||.|:||  ..:|.:...|.|..|.||:::||||..||.:|||:|::.|..:|..||..:.||
Zfish    66 RFVEKEIKK--ANIPTMDTGENPEVPFPRDMIDLEATFEKLENELKEINTNQEALKKNFLELTEL 128

  Fly   131 KYVLENTEGFFSDQEVINL--DVNRKLDPEDPANLPGAAQRG---QLAFVAGVIKLERFFSFERM 190
            |::|..|:.||.:.|..||  :.:..|||.:       |.||   :|.||||||..||..:||||
Zfish   129 KHILRRTQQFFDEMEDPNLLEESSSLLDPSE-------AGRGAPLRLGFVAGVINRERIPTFERM 186

  Fly   191 LWRISRGNIFLRRADIDGLVADEETGRPVLKTVFVAFFQGEQLKQRIKKVCTGYHAAVYPCPSSH 255
            |||:.|||:|||:.:|:..:.|..||..|.|:||:.||||:|||.|:||:|.|:.|::||||.:.
Zfish   187 LWRVCRGNVFLRQTEIEDPLEDPTTGDQVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETP 251

  Fly   256 AERKEMIKDVNVRLEDLKLVLSQSADHRSRVLNSASKHLPRWSIMVRKMKAIYHILNFFNPDVTG 320
            .|||||...||.|::||::||:|:.|||.|||.:|:|.:..|.|.|||||||||.||..|.|||.
Zfish   252 QERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKTMRVWFIKVRKMKAIYHTLNLCNIDVTQ 316

  Fly   321 KCLIGEGWVPTNDISTVQDALARASKISESSIPAFMNVIETNEMPPTYTRTNKFTNGFQNLVDSY 385
            ||||.|.|.|.:|:.::|.||.|.::.|.|::|:.:|.::|.:.||||.:|||||:||||:||:|
Zfish   317 KCLIAEVWCPVSDLDSIQFALRRGTERSGSTVPSILNRMQTKQTPPTYNKTNKFTSGFQNIVDAY 381

  Fly   386 GMASYREVNPALYACITFPFLFAVMFGDLGHGLILLLFASWLIIKEKQLSSIK--EEIFNIFFGG 448
            |:.:|||:|||.|..|||||||||||||:|||:::...|.:|:::|.:|.:.|  .|:||:.|.|
Zfish   382 GIGTYREINPAPYTIITFPFLFAVMFGDMGHGVLMTSAALYLVLRETRLLAQKSDNEMFNMIFAG 446

  Fly   449 RYIIFLMGIFSIYTGFIYNDVFSKSMNIFGSAWHM--------NYTRDVVEDENLKYITLRPNDT 505
            ||||.|||:||:|||.||||.||||:|:|.|.|.:        |:|...:|..::..:....:..
Zfish   447 RYIILLMGMFSVYTGLIYNDCFSKSLNMFSSGWSVRPMFAPNGNWTDQTLESNSVLQLNPSVSGV 511

  Fly   506 VYKTYPFGMDPIWQLADNKIIFLNTFKMKLSIIVGVIHMIFGVSMSVVNFAYYKKYASIFLEFLP 570
            ....||.|:||||.:|.||:.|||:||||:|:|:|||||:|||::|:.|..|:||..:|||.|:|
Zfish   512 FGGPYPLGIDPIWNIAANKLTFLNSFKMKMSVILGVIHMLFGVTLSLFNHLYFKKPLNIFLNFIP 576

  Fly   571 QVLFLLLLFGYMVFMMFFKWVVYNDTVEGPLSPACAPSILILFINMILQGSQDTPEPCKEFMFDG 635
            :::|:..||||::.::|:||:.|:     .::...|||:||.||||.|....|   |..:.::.|
Zfish   577 EIVFMSSLFGYLILLIFYKWIAYD-----AVTSKDAPSLLIAFINMCLFNYND---PTNKPLYRG 633

  Fly   636 QKSIQQVFVVVAIICIPWMLLGKPLYI-----------------------MIKRKTNGAPPPKPQ 677
            |..||.:.||:|:.|:|.||:.|.:.:                       .:::....:||...|
Zfish   634 QAGIQSLLVVIALACVPVMLVVKTMILRRQHLWKKHLSQMRDARPAENLETLEQTGTSSPPGLTQ 698

  Fly   678 SG-------------------------------GGEGHGEDD--EMGEIFIHQAIHTIEYVLSTV 709
            .|                               .|:.|.|::  ..|::.:|||||||||.|..:
Zfish   699 QGTQKFGGVRVGNGPTEDEAEIIDHDQLSQHSEEGDEHSEEEPFNFGDMAVHQAIHTIEYCLGCI 763

  Fly   710 SHTASYLRLWALSLAHAQLSEVLWNMVFSMGFKYDSYIGGILIYVFFGAWALLTVGILVLIEGLS 774
            |:||||||||||||||||||||||.||..:|....|..|...:.:.|.|:|.|||.||:::||||
Zfish   764 SNTASYLRLWALSLAHAQLSEVLWGMVMRLGLSSRSGGGFFGLSIIFSAFATLTVCILLIMEGLS 828

  Fly   775 AFLHTLRLHWVEFMSKFYEGAGYAFEPFAFKTILDVSEDD 814
            ||||.||||||||.:|||.|.|:.|.||:|::||:...|:
Zfish   829 AFLHALRLHWVEFQNKFYTGQGFKFVPFSFESILEGRFDE 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-5	NP_609515.1	V_ATPase_I	27..804	CDD:460232	396/847 (47%)
atp6v0a1b	XP_009295518.1	V_ATPase_I	27..858	CDD:460232	396/847 (47%)