Protein Alignment Vha100-5 and LOC3290488

DIOPT Version :10

• Sequence 1: NP_609515.1
• Gene: Vha100-5 / 34587
• FlyBaseID: FBgn0032373
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_321521.3
• Gene: LOC3290488 / 3290488
• VectorBaseID: AGAMI1_011388
• Length: 831
• Species: Anopheles gambiae
• Alignment Length: 836
• Identity: 532/836 - (63%)
• Similarity: 643/836 - (76%)
• Gaps: 29/836 - (3%)

  Fly     1 MGDMFRSEKMALCQLFIQPEAAYASIAELGEKGCVQFRDLNEEVSAFQRKYVNEVRRCDDMERRL 65
            |..|||||:|||||:||||||||.|::||||.|.|||||||.:|:|||||:|:||||||:|||:|
Mosquito     1 MAMMFRSEEMALCQMFIQPEAAYTSVSELGETGAVQFRDLNADVNAFQRKFVSEVRRCDEMERKL 65

  Fly    66 RYVESEMKKDEVKLPVLRPEEEPIAPNPREIVDLEAQLEKTDNELREMSANGASLDANFRHMQEL 130
            ||||.|:|||.|::|....::.|.|||||||:||||:||||:||:.|:|.|..:|.:|:..:.||
Mosquito    66 RYVEGEVKKDSVQIPECSVDDWPRAPNPREIIDLEARLEKTENEILELSQNAVNLKSNYLELTEL 130

  Fly   131 KYVLENTEGFFSDQEVI-NLDVNR-KLDPEDPANLPGAAQRGQLAFVAGVIKLERFFSFERMLWR 193
            |:|||.|:.||.:|||| :.|..: .|..|||.   .|..||:|.||||||:.|:...|||||||
Mosquito   131 KHVLERTQSFFFEQEVIVSTDAAKSNLIAEDPT---AAQSRGRLGFVAGVIQREKMPGFERMLWR 192

  Fly   194 ISRGNIFLRRADIDGLVADEETGRPVLKTVFVAFFQGEQLKQRIKKVCTGYHAAVYPCPSSHAER 258
            |||||||||:.:::..:.|..||..:.||||||||||||||.||||||||||.::||||||.:||
Mosquito   193 ISRGNIFLRQVELEEPLEDPATGNEIFKTVFVAFFQGEQLKARIKKVCTGYHVSLYPCPSSGSER 257

  Fly   259 KEMIKDVNVRLEDLKLVLSQSADHRSRVLNSASKHLPRWSIMVRKMKAIYHILNFFNPDVTGKCL 323
            .:|:|.|..|||||::||:|:.|||:.||.|.:|.|..|.|||:|||||||.||.||.|||.|||
Mosquito   258 TDMVKGVCTRLEDLRMVLNQTQDHRAIVLASVAKELFSWRIMVKKMKAIYHTLNLFNMDVTKKCL 322

  Fly   324 IGEGWVPTNDISTVQDALARASKISESSIPAFMNVIETNEMPPTYTRTNKFTNGFQNLVDSYGMA 388
            |||.|||..|:..||.||:..|....|:||:|:|||:|||.||||.||||||.|||||:|:||:|
Mosquito   323 IGECWVPVPDLPKVQKALSDGSAAVGSTIPSFLNVIDTNEAPPTYNRTNKFTRGFQNLIDAYGIA 387

  Fly   389 SYREVNPALYACITFPFLFAVMFGDLGHGLILLLFASWLIIKEKQLSSIK--EEIFNIFFGGRYI 451
            ||||.|||||..|||||||.:||||||||:|:.||..|::..||:|.:.|  .||:|||||||||
Mosquito   388 SYREANPALYTIITFPFLFGIMFGDLGHGMIMALFGLWMVTGEKKLGAKKSTNEIWNIFFGGRYI 452

  Fly   452 IFLMGIFSIYTGFIYNDVFSKSMNIFGSAWHMNYTRDVVEDENLKYITLRPNDTVYKT--YPFGM 514
            |.|||:||:||||:|||:||||||||||||.:||....|...  |.:||.|..|.|.|  ||.|:
Mosquito   453 ILLMGLFSMYTGFVYNDIFSKSMNIFGSAWSINYNTSTVMTN--KDLTLNPGSTDYDTEIYPIGL 515

  Fly   515 DPIWQLADNKIIFLNTFKMKLSIIVGVIHMIFGVSMSVVNFAYYKKYASIFLEFLPQVLFLLLLF 579
            ||:||||.|||||||::|||||||.||:||||||.|||||..::||..||.||||||::||:|||
Mosquito   516 DPVWQLASNKIIFLNSYKMKLSIIFGVVHMIFGVCMSVVNHNFFKKRISIVLEFLPQIIFLVLLF 580

  Fly   580 GYMVFMMFFKWVVYN-DTVEGPLSPACAPSILILFINMILQGSQDTPEPCKEFMFDGQKSIQQVF 643
            .|||||||.||:.|. .|...|.:|.||||:||:||||:|..:.:....|.||||:||..:|:.|
Mosquito   581 AYMVFMMFMKWIAYTAKTDYQPRTPGCAPSVLIMFINMMLFKNSEPFHGCDEFMFEGQNELQRTF 645

  Fly   644 VVVAIICIPWMLLGKPLYIMIKRKTNGAPPPKPQSG----GGEGH----------GEDDE-MGEI 693
            |.:|::||||||||||.|:|.||| |.:|.|.|.:|    ||:.:          ..||| |.||
Mosquito   646 VFIALLCIPWMLLGKPFYLMFKRK-NASPTPIPNNGDVHQGGDANHTSSSPKPHDSHDDEPMAEI 709

  Fly   694 FIHQAIHTIEYVLSTVSHTASYLRLWALSLAHAQLSEVLWNMVFSMGFKYDSYIGGILIYVFFGA 758
            |||||||||||||||||||||||||||||||||||||||||||.|||.|..||.|.|::|..|||
Mosquito   710 FIHQAIHTIEYVLSTVSHTASYLRLWALSLAHAQLSEVLWNMVLSMGLKQTSYKGAIMLYFVFGA 774

  Fly   759 WALLTVGILVLIEGLSAFLHTLRLHWVEFMSKFYEGAGYAFEPFAFKTILDVSEDD 814
            |:|.|:.|||::||||||||||||||||||||||||.||.|:||:||.|:| |:||
Mosquito   775 WSLFTLAILVMMEGLSAFLHTLRLHWVEFMSKFYEGLGYGFQPFSFKLIID-SDDD 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-5	NP_609515.1	V_ATPase_I	27..804	CDD:460232	505/798 (63%)
LOC3290488	XP_321521.3	None