Protein Alignment Vha100-5 and Vha100-3

DIOPT Version :10

• Sequence 1: NP_609515.1
• Gene: Vha100-5 / 34587
• FlyBaseID: FBgn0032373
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Alignment Length: 917
• Identity: 325/917 - (35%)
• Similarity: 495/917 - (53%)
• Gaps: 147/917 - (16%)

  Fly     5 FRSEKMALCQLFIQPEAAYASIAELGEKGCVQFRDLNEEVSAFQRKYVNEVRRCDDMERRLRYVE 69
            ||||.|.||||.:..|.|:..:.|:|..|.|||.::.:|.......|..:|.:|.::   ||.|:
  Fly    15 FRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYEL---LRIVD 76

  Fly    70 S------EMKKDEVKLPVLRPEEEPIAPNPREIVDLEAQLEKTD-----NELREMSANGAS---- 119
            |      ::..:|:..|               .||.|.:|::.|     :.|:.:....::
  Fly    77 SLHTYIVQLHVNEIFYP---------------DVDRENRLKEKDLAKYSDSLKRIHVEASAVTEH 126

  Fly   120 ---LDANFRHMQELKYVLE----------NTEGFFSDQEVINLDVNRKLDPEDPANLPGAAQRGQ 171
               ||:....|.|..:.|.          .:|..:|:..||.|       .:|.....| |....
  Fly   127 YYRLDSRRNRMMEHSFALNKANKYMVSDMGSELLYSESTVIGL-------VQDATTTSG-AYPAH 183

  Fly   172 LAFVAGVIKLERFFSFERMLWRISRGNIFLRRADIDGLVADEETG-RP--VLKTVFVAFFQGEQL 233
            |.::.|.|:.::|:|||.:|:|:...|:.:|.:::...|.:...| :|  |.|...:.......:
  Fly   184 LNYMIGCIRADKFYSFELLLYRLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMI 248

  Fly   234 KQRIKKVCTGYHAAVYPCPSSHAERKEMIKDVNVRLEDLKLVLSQSADHRSRVLNSASKHLPRWS 298
            ..::.|:|..||..:|.||||.::|::.:|:::..:.:::.||.::...|.::|..|.:.|....
  Fly   249 WPKVLKICAHYHVNIYDCPSSASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIR 313

  Fly   299 IMVRKMKAIYHILNFFNPDVTG-----KCLIGEGWVPTNDISTVQDALARASKIS------ESSI 352
            :.:||...:|.::|...  :.|     :.|:.|.::|::|:..|:..|..||:||      :||.
  Fly   314 VNLRKALKVYDLMNRLR--LVGGVEVPRYLLAEVYIPSSDVPEVEVILRNASRISGGADNIDSSD 376

  Fly   353 PAFMNVIET--------------------------------NEMPPTYTRTNKFTNGFQNLVDSY 385
            ...||.::|                                |.|||||.|.||||.|||||:|:|
  Fly   377 EDEMNDMKTMPNTTPYPIEADFQPLEDMSAGAILLKKNRLVNHMPPTYFRLNKFTRGFQNLIDAY 441

  Fly   386 GMASYREVNPALYACITFPFLFAVMFGDLGHGLILLLFASWLIIKEKQL------SSIKEEIFNI 444
            |||.|:|:|||.|..|||||||||||||||||::|:||:|.:|.|.:::      ::.:.||.||
  Fly   442 GMADYKELNPAPYTIITFPFLFAVMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNI 506

  Fly   445 FFGGRYIIFLMGIFSIYTGFIYNDVFSKSMNIFGSAWHMNYTRDVVEDENLKYITL---RPNDTV 506
            .:.|||||.|||:||:|.|.:||.|.:|..|:|||:|...|....|.|... ::||   .|:...
  Fly   507 LYAGRYIILLMGVFSVYMGLVYNIVMAKGFNLFGSSWSCRYNETTVYDPAF-HVTLDSSHPHFYS 570

  Fly   507 YKTYPFGMDPIWQL-ADNKIIFLNTFKMKLSIIVGVIHMIFGVSMSVVNFAYYKKYASIFLEFLP 570
            ...||.||||:|.: ..:.|...|:.|||::|::|:..|:||:.::..|.....:.|.:.|..:|
  Fly   571 GHPYPLGMDPVWAVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIP 635

  Fly   571 QVLFLLLLFGYMVFMMFFKWVVYNDTVEGPLSPACAPSILILFINMILQGSQDTPEPCKEFMFDG 635
            |::|:|.||||:||::|:||:.|......|.:.|||||:||.||||:|...:|..|.|.::|:..
  Fly   636 QMIFMLCLFGYLVFLIFYKWMSYGGHKPAPYNAACAPSVLITFINMMLMKKEDPVENCLDYMYPN 700

  Fly   636 QKSIQQVFVVVAIICIPWMLLGKPLYIMIKRK-----------------------------TNGA 671
            ::.|:...|.:|...||.:|.|||:|:|.:|:                             .:.:
  Fly   701 ERMIEFALVGIAFCTIPILLAGKPIYLMRRRRKMQQERERDFKRMRRQTIAEMRSTMRYTDDDNS 765

  Fly   672 PPPKPQSGGGEGHGEDDEMGEIFIHQAIHTIEYVLSTVSHTASYLRLWALSLAHAQLSEVLWNMV 736
            ...:.:|...|   |:.||.||:||..|||||.||.:|||||||||||||||||.|||:|||:||
  Fly   766 ETSRQKSVDNE---EEHEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMV 827

  Fly   737 FSMGF--KYDSYIGGILIYVFFGAWALLTVGILVLIEGLSAFLHTLRLHWVEFMSKFYEGAGYAF 799
            .:.||  ....|.|..::...|.|||:|||.|||::|||||||||||||||||.|||:.|||.:|
  Fly   828 LTKGFANTLPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGESF 892

  Fly   800 EPFAFKT 806
            :.|.|.|
  Fly   893 KAFNFPT 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-5	NP_609515.1	V_ATPase_I	27..804	CDD:460232	312/891 (35%)
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:460232	312/890 (35%)