Protein Alignment Vha100-5 and vha-7

DIOPT Version :9

• Sequence 1: NP_001260388.1
• Gene: Vha100-5 / 34587
• FlyBaseID: FBgn0032373
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_001379486.1
• Gene: vha-7 / 178219
• WormBaseID: WBGene00006916
• Length: 1210
• Species: Caenorhabditis elegans
• Alignment Length: 909
• Identity: 354/909 - (38%)
• Similarity: 509/909 - (55%)
• Gaps: 116/909 - (12%)

  Fly     4 MFRSEKMALCQLFIQPEAAYASIAELGEKGCVQFRDLNEEVSAFQRKYVNEVRRCDDMERRLRYV 68
            ||||:.|.|.|:.:..|||:..:||:|:.|.|||.|||.::|.:.|.:|.::|||::|||:||::
 Worm   292 MFRSDPMKLYQMILVKEAAFECVAEIGKHGNVQFVDLNAKMSLYSRTFVKQMRRCEEMERKLRFL 356

  Fly    69 ESEMKKDEVKLPVLRPEE----EPIAPNPREIVDLEAQLEKTDNELREMSANGASLDANFRHMQE 129
            |.::...:   |.|.|:.    :..||...|::.||.:|::.:.|..:::.|..:|..|....:|
 Worm   357 EKQVITCK---PGLDPKSIDYTDLSAPTQAEMIQLEHKLDQLEREFLDLNNNDYALRKNLNSSKE 418

  Fly   130 LKYVLENTEGFFS--DQEVINLDVNRKLDPED-------------PAN-----LPGAAQRGQLAF 174
            ...|:...:.||.  .:|.......|....:|             |::     .|.........|
 Worm   419 FLQVMRLVDEFFQVHKEEEAKARFERSATTDDIEMFSKSFGFGGLPSSNEMPLTPLLGSDDNAWF 483

  Fly   175 VAGVIKLERFFSFERMLWRISRGNIFLRRADIDGLVADEETGRPVLKTVFVAFFQGEQLKQRIKK 239
            ||||:.|::..||||:|||..|...|:|.:|....|.|..|..|:.|.||:.||:||.|:..::|
 Worm   484 VAGVLPLDKKESFERVLWRACRRTAFVRTSDASFTVNDPVTLEPLQKCVFIVFFKGESLRLIVEK 548

  Fly   240 VCTGYHAAVYPCPSSHAERKEMIKDVNVRLEDLKLVLSQSADHRSRVLNSASKHLPRWSIMVRKM 304
            ||.|::|..||||.|..:||..:.:...|:.||.:|:..:..||..:|...|..:|.|...::..
 Worm   549 VCDGFNATQYPCPKSSKDRKMKMSETEGRMNDLTVVIDTTQTHRYTILKDMSFEIPIWLKNIQIQ 613

  Fly   305 KAIYHILNFFNPDVTGKCLIGEGWVPTNDISTVQDALARASKISESSIPAFMNVIETNEMPPTYT 369
            |:::.::|.|..|..| .|.||.|:|..:...|:.||....|.|.:.:...:|.:.||..|||:.
 Worm   614 KSVFAVMNMFTVDTNG-FLAGECWIPAAEEDDVRQALHDGFKASGTEVEPILNELWTNAPPPTFH 677

  Fly   370 RTNKFTNGFQNLVDSYGMASYREVNPALYACITFPFLFAVMFGDLGHGLILLLFASWLIIKEKQL 434
            |||||||.||::|||||::.|.|||||.|..|||||||||||||..||.||||.|.:.|..|:::
 Worm   678 RTNKFTNVFQSIVDSYGVSQYCEVNPAPYTIITFPFLFAVMFGDAAHGAILLLAALFFIRNERKI 742

  Fly   435 SS--IKEEIFNIFFGGRYIIFLMGIFSIYTGFIYNDVFSKSMNIFGSAW---------------- 481
            .|  |::||||.|:|||||:.|||||||||||:|||.|:||.|:|||.|
 Worm   743 ESKKIRDEIFNTFYGGRYIMMLMGIFSIYTGFLYNDAFAKSFNVFGSGWSNSYNETQLDWWIARS 807

  Fly   482 ---HMNYTRDVVEDENLKYITLRPNDTVYKTYPFGMDPIWQLADNKIIFLNTFKMKLSIIVGVIH 543
               |..|:.::|.:::.         .:.||||||:||||.:|||::.|||:.|||.|:|:|:..
 Worm   808 YRKHREYSLELVPEKSF---------DIEKTYPFGVDPIWNIADNRLSFLNSMKMKASVIIGITQ 863

  Fly   544 MIFGVSMSVVNFAYYKKYASIFLEFLPQVLFLLLLFGYMVFMMFFKWVVYN---DTVEGPLSPA- 604
            |.|||.:||:|..::|.|..|...|:|||:||..:|.|:...:..||:.::   :.|.|...|.
 Worm   864 MTFGVFLSVLNHIHFKSYIDIISNFIPQVIFLSCIFIYLCIQIIVKWIFFSVNAENVFGFEYPGS 928

  Fly   605 -CAPSILILFINMI---------LQGSQDTPEPCK-EFMFDGQKSIQQVFVVVAIICIPWMLLGK 658
             ||||:||..|||.         |..:.:....|. .:.:..|:.::.:.:.:::.|||.||.||
 Worm   929 HCAPSLLIGLINMFMFKKRNEGYLNENGEVYSNCHLGYWYPNQRLVETILISISLACIPIMLFGK 993

  Fly   659 PLYIMI---KR------------KTNG---APPPKPQSGGGEGHGEDDE---------------- 689
            ||::..   ||            :.||   :.|..|....|....||.|
 Worm   994 PLWVRFVTSKRHKLQENKSLKSLRRNGTTVSAPTSPVVDAGPPRFEDAELLLADELDIGEDIHHS 1058

  Fly   690 MGEIFIHQAIHTIEYVLSTVSHTASYLRLWALSLAHAQLSEVLWNMVFSMGFKYDSYIGG----- 749
            :.:||:||||||||:||..|||||||||||||||||||||||:|:||...|.....:|..
 Worm  1059 LSDIFVHQAIHTIEFVLGCVSHTASYLRLWALSLAHAQLSEVMWHMVLIQGIHTVDHIENETIAM 1123

  Fly   750 ----ILIYVFFGAWALLTVGILVLIEGLSAFLHTLRLHWVEFMSKFYEGAGYAFEPFAFKTILD 809
                ::..|.|..:|.|::.||:::||||||||.||||||||.||||.|.|:.|..|..|..|:
 Worm  1124 CLKPVVACVAFFIFASLSLSILIMMEGLSAFLHALRLHWVEFQSKFYLGTGHPFHAFYLKESLE 1187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-5	NP_001260388.1	NtpI	5..805	CDD:224188	351/902 (39%)
		V_ATPase_I	28..804	CDD:279793	341/878 (39%)
vha-7	NP_001379486.1	V_ATPase_I	315..1181	CDD:396194	341/878 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53812
OrthoDB	1	1.010	-	-		D164762at33208
OrthoFinder	1	1.000	-	-		FOG0000328
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100301
Panther	1	1.100	-	-	O	PTHR11629
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X226
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930