Protein Alignment Vha100-5 and Atp6v0a2

DIOPT Version :9

• Sequence 1: NP_001260388.1
• Gene: Vha100-5 / 34587
• FlyBaseID: FBgn0032373
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_446227.2
• Gene: Atp6v0a2 / 116455
• RGDID: 621006
• Length: 856
• Species: Rattus norvegicus
• Alignment Length: 876
• Identity: 377/876 - (43%)
• Similarity: 544/876 - (62%)
• Gaps: 85/876 - (9%)

  Fly     1 MGDMFRSEKMALCQLFIQPEAAYASIAELGEKGCVQFRDLNEEVSAFQRKYVNEVRRCDDMERRL 65
            ||.:||||.|.|.|||:|...||..::.|||||.|||||||:.||:||||:|.||:||:::||.|
  Rat     1 MGSLFRSESMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERIL 65

  Fly    66 RYVESEMKKDEVKLPVLRPEEEPIAPNPREIVDLEAQLEKTDNELREMSANGASLDANFRHMQEL 130
            .|:..|:.:.::.||  ..|..|.||..:.:::::.||:|.:.||||::.|...|..|...:.|.
  Rat    66 VYLVQEITRADIPLP--EGEASPPAPPVKHVLEMQEQLQKLEVELREVTKNKEKLRKNLLELVEY 128

  Fly   131 KYVLENTEGFF--------SDQEVINLDVNRKLDPEDPANLPGAAQRGQLAFVAGVIKLERFFSF 187
            .::|..|:.|.        :.:|...|:.:..||......| ||    :|.||:|:|:..:..:|
  Rat   129 THMLRVTKTFLKRNVEFEPTYEEFPALESDSLLDYSCMQRL-GA----KLGFVSGLIQQGKVEAF 188

  Fly   188 ERMLWRISRGNIFLRRADIDGLVADEETGRPVLKTVFVAFFQGEQLKQRIKKVCTGYHAAVYPCP 252
            ||||||..:|...:..|::|..:.|.|||..:...||:..|.|||:..::||:|..||..:||.|
  Rat   189 ERMLWRACKGYTIVTYAELDEALEDPETGEVIKWYVFLISFWGEQIGHKVKKICDCYHCHIYPYP 253

  Fly   253 SSHAERKEMIKDVNVRLEDLKLVLSQSADHRSRVLNSASKHLPRWSIMVRKMKAIYHILNFFNPD 317
            ::..||:|:.:.:|.|::||..||.::.|:..:||..|::.:....|.|||||||||:||..:.|
  Rat   254 NTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVCSRVIQVRKMKAIYHMLNMCSFD 318

  Fly   318 VTGKCLIGEGWVPTNDISTVQDALARASKISESSIPAFMNVIETNEMPPTYTRTNKFTNGFQNLV 382
            ||.||||.|.|.|..|:..::.||...|:.|.::||:|||.|.|.|.|||..||||||.||||:|
  Rat   319 VTNKCLIAEVWCPEVDLPGLRRALEEGSRESGATIPSFMNTIPTKETPPTLIRTNKFTEGFQNIV 383

  Fly   383 DSYGMASYREVNPALYACITFPFLFAVMFGDLGHGLILLLFASWLIIKEK--QLSSIKEEIFNIF 445
            |:||:.|||||||||:..|||||||.|||||||||.::.|||..|::.|.  :||. .:||..:|
  Rat   384 DAYGVGSYREVNPALFTIITFPFLFGVMFGDLGHGFVMFLFALLLVLNENHPRLSQ-SQEILRMF 447

  Fly   446 FGGRYIIFLMGIFSIYTGFIYNDVFSKSMNIFGSAWHMN--YTRDVVEDENLKYI-----TLRPN 503
            |.||||:.|||:||:|||.||||.||||:|:|||.|:::  |:.....:|..|.:     |:|.:
  Rat   448 FDGRYILLLMGLFSVYTGLIYNDCFSKSLNLFGSGWNVSAMYSSSHSPEEQRKMVLWNDSTIRHS 512

  Fly   504 DT---------VYK-TYPFGMDPIWQLADNKIIFLNTFKMKLSIIVGVIHMIFGVSMSVVNFAYY 558
            .|         |:: .||||:||||.||.|::.|||:||||:|:|:|:.||.|||.:.:.|..::
  Rat   513 RTLQLDPNIPGVFRGPYPFGIDPIWNLATNRLTFLNSFKMKMSVILGIFHMTFGVILGIFNHLHF 577

  Fly   559 KKYASIFLEFLPQVLFLLLLFGYMVFMMFFKWVVYNDTVEGPLSPACAPSILILFINMILQGSQD 623
            :|..:|:|..:|::||:|.:|||::||:.:||:.|:......     ||||||.||||.|..|.:
  Rat   578 RKKFNIYLVSVPEILFMLCIFGYLIFMIIYKWLAYSAETSRE-----APSILIEFINMFLFPSSE 637

  Fly   624 TPEPCKEFMFDGQKSIQQVFVVVAIICIPWMLLGKPLYIM------------------------- 663
            |     ..::.||..:|:|.:.:.::.:|.:.|||||:::
  Rat   638 T-----HGLYPGQAHVQKVLLALTVLAVPVLFLGKPLFLLWLHNGRSCFGVSRSGYTLVRKDSEE 697

  Fly   664 ---------IKRKTNGAPPPKPQSGGGEGHGEDDEMGEIFIHQAIHTIEYVLSTVSHTASYLRLW 719
                     |:...|     :.:.|..|...|:...|||.:.||||:|||.|..:|:||||||||
  Rat   698 EVSLLGSQDIEEGNN-----RMEEGCREMTCEEFNFGEILMTQAIHSIEYCLGCISNTASYLRLW 757

  Fly   720 ALSLAHAQLSEVLWNMVFSMGFKYDSYIGGILIYVFFGAWALLTVGILVLIEGLSAFLHTLRLHW 784
            ||||||||||:|||.|:..:|.:.|:..|.:|:......:|:|||.||:::||||||||.:||||
  Rat   758 ALSLAHAQLSDVLWAMLMRVGLRVDNTYGVLLLLPVMTFFAVLTVFILLVMEGLSAFLHAIRLHW 822

  Fly   785 VEFMSKFYEGAGYAFEPFAFKTILD-VSEDD 814
            |||.:|||.|||..|.||:|..:.. .|:||
  Rat   823 VEFQNKFYVGAGTKFVPFSFSLLSSKFSKDD 853

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-5	NP_001260388.1	NtpI	5..805	CDD:224188	371/860 (43%)
		V_ATPase_I	28..804	CDD:279793	359/836 (43%)
Atp6v0a2	NP_446227.2	NtpI	5..839	CDD:224188	369/856 (43%)
		V_ATPase_I	28..839	CDD:279793	357/833 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D164762at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010