DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek2 and Lrrc17

DIOPT Version :9

Sequence 1:NP_523551.1 Gene:kek2 / 34582 FlyBaseID:FBgn0015400 Length:894 Species:Drosophila melanogaster
Sequence 2:NP_083253.1 Gene:Lrrc17 / 74511 MGIID:1921761 Length:443 Species:Mus musculus


Alignment Length:251 Identity:64/251 - (25%)
Similarity:91/251 - (36%) Gaps:93/251 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 QTVECGGQQLSNLPEGMDPGTQVLNFSGNALQVLQSERFLRMDLLNLQKIYLSRNQLIRIHEKAF 98
            ||::|..::|..:|..:.|....|:.|.|.::.|:.:.|  .|:..|:|:.||.|.:..|...||
Mouse   252 QTLDCKRKELKKVPSNIPPDIVKLDLSSNKIRQLRPKEF--EDVHELKKLNLSSNGIEFIDPAAF 314

  Fly    99 RGLTNLVELDLSENALQNVPSETFQDYSSLMRLSLSGNPIRELKTSAFRHLSFLTTLELSNCQVE 163
            .||.:|.|||||.|:|||.      ||..|                  ..|.||..|        
Mouse   315 LGLIHLEELDLSNNSLQNF------DYGVL------------------EDLYFLKLL-------- 347

  Fly   164 RIENEAFVGMDNLEWLRLDGNRIGFIQGTHILPKSLHGISLHSNRWNCDCRLLDIHFWL-----V 223
                          |||                         .|.|.||..:..:::||     |
Mouse   348 --------------WLR-------------------------DNPWRCDYSIHYLYYWLKHHYNV 373

  Fly   224 NYNTPLAEEPKCMEPARLK----GQVIKSLQRE----QLACLPEVSPQSSYTEVSE 271
            :||     ..:|..|...|    |:.::|...|    :|...||...|.  ||..|
Mouse   374 HYN-----GLECKTPEEYKGWSVGKYVRSYYEECPKDKLPAYPETFDQD--TEDDE 422

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek2NP_523551.1 leucine-rich repeat 34..52 CDD:275380 5/17 (29%)
leucine-rich repeat 54..79 CDD:275380 6/24 (25%)
LRR_8 79..138 CDD:290566 23/58 (40%)
LRR_RI <80..187 CDD:238064 30/106 (28%)
leucine-rich repeat 80..103 CDD:275380 10/22 (45%)
leucine-rich repeat 104..127 CDD:275380 12/22 (55%)
LRR_8 126..186 CDD:290566 8/59 (14%)
leucine-rich repeat 128..151 CDD:275380 2/22 (9%)
leucine-rich repeat 152..175 CDD:275380 2/22 (9%)
leucine-rich repeat 176..198 CDD:275380 3/21 (14%)
TPKR_C2 207..256 CDD:301599 16/61 (26%)
I-set 258..361 CDD:254352 6/14 (43%)
Ig_2 263..361 CDD:290606 4/9 (44%)
Lrrc17NP_083253.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 20..48
leucine-rich repeat 65..83 CDD:275380
LRR 1 84..105
leucine-rich repeat 85..108 CDD:275380
LRR_8 86..143 CDD:290566
LRR_4 107..148 CDD:289563
LRR 2 108..129
leucine-rich repeat 109..132 CDD:275380
LRR 3 132..153
leucine-rich repeat 133..156 CDD:275380
leucine-rich repeat 157..207 CDD:275380
TPKR_C2 165..>201 CDD:301599
leucine-rich repeat 208..245 CDD:275380
leucine-rich repeat 251..271 CDD:275380 5/18 (28%)
LRR_RI <270..352 CDD:238064 37/154 (24%)
LRR 4 271..292 5/22 (23%)
leucine-rich repeat 272..295 CDD:275380 6/24 (25%)
LRR_8 274..330 CDD:290566 23/57 (40%)
LRR 5 295..316 8/20 (40%)
LRR_4 296..334 CDD:289563 20/43 (47%)
leucine-rich repeat 296..319 CDD:275380 10/22 (45%)
LRR 6 319..342 13/46 (28%)
leucine-rich repeat 320..343 CDD:275380 14/46 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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