DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek2 and Rtn4r

DIOPT Version :9

Sequence 1:NP_523551.1 Gene:kek2 / 34582 FlyBaseID:FBgn0015400 Length:894 Species:Drosophila melanogaster
Sequence 2:NP_075358.1 Gene:Rtn4r / 65079 MGIID:2136886 Length:473 Species:Mus musculus


Alignment Length:353 Identity:96/353 - (27%)
Similarity:132/353 - (37%) Gaps:85/353 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SGLPIWIPLLALLAITAACPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFSGNALQV 66
            |.|..|:..|....:...| |..||| :...|.|..|..|.|..:|.|:...:|.:...||.:..
Mouse     9 SRLLAWVLWLQAWRVATPC-PGACVC-YNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISH 71

  Fly    67 LQSERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENA------------------ 113
            :.:..|  ....||..::|..|.|.||...||.|||.|.:||||:||                  
Mouse    72 VPAASF--QSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHT 134

  Fly   114 -------------------------------LQNVPSETFQDYSSLMRLSLSGNPIRELKTSAFR 147
                                           ||.:|..||:|..:|..|.|.||.|..:...|||
Mouse   135 LHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFR 199

  Fly   148 HLSFLTTLELSNCQVERIENEAFVGMDNLEWLRLDGNRIGFIQGTHILP-KSLHGISLHSNRWNC 211
            .|..|..|.|....|.|:...||..:..|..|.|..|.:..:....::| :||..:.|:.|.|.|
Mouse   200 GLHSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRLNDNPWVC 264

  Fly   212 DCRLLDIHFWLVNYNTPLAEEPKCMEPARLKGQVIKSL------------------QREQL---- 254
            |||...:..||..:....:|.| |..|.||..:.:|.|                  |..||    
Mouse   265 DCRARPLWAWLQKFRGSSSEVP-CNLPQRLADRDLKRLAASDLEGCAVASGPFRPIQTSQLTDEE 328

  Fly   255 ------ACLPEVSPQSSYTEVSEGRNMS 276
                  .|.|:.:.::|..|  .||..|
Mouse   329 LLSLPKCCQPDAADKASVLE--PGRPAS 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek2NP_523551.1 leucine-rich repeat 34..52 CDD:275380 6/17 (35%)
leucine-rich repeat 54..79 CDD:275380 4/24 (17%)
LRR_8 79..138 CDD:290566 30/107 (28%)
LRR_RI <80..187 CDD:238064 45/155 (29%)
leucine-rich repeat 80..103 CDD:275380 10/22 (45%)
leucine-rich repeat 104..127 CDD:275380 13/71 (18%)
LRR_8 126..186 CDD:290566 21/59 (36%)
leucine-rich repeat 128..151 CDD:275380 10/22 (45%)
leucine-rich repeat 152..175 CDD:275380 7/22 (32%)
leucine-rich repeat 176..198 CDD:275380 5/22 (23%)
TPKR_C2 207..256 CDD:301599 19/76 (25%)
I-set 258..361 CDD:254352 6/19 (32%)
Ig_2 263..361 CDD:290606 5/14 (36%)
Rtn4rNP_075358.1 LRR 1 58..79 4/22 (18%)
LRR_8 60..115 CDD:290566 21/56 (38%)
leucine-rich repeat 60..82 CDD:275380 4/23 (17%)
LRR 2 82..103 9/20 (45%)
leucine-rich repeat 83..106 CDD:275380 10/22 (45%)
LRR_RI <90..>166 CDD:238064 16/75 (21%)
LRR 3 106..128 7/21 (33%)
leucine-rich repeat 107..131 CDD:275380 7/23 (30%)
LRR_8 131..190 CDD:290566 11/58 (19%)
LRR 4 131..152 0/20 (0%)
leucine-rich repeat 132..155 CDD:275380 0/22 (0%)
LRR 5 155..176 5/20 (25%)
LRR_4 156..195 CDD:289563 12/38 (32%)
leucine-rich repeat 156..179 CDD:275380 6/22 (27%)
LRR_8 179..238 CDD:290566 21/58 (36%)
LRR 6 179..200 8/20 (40%)
leucine-rich repeat 180..203 CDD:275380 10/22 (45%)
LRR 7 203..224 7/20 (35%)
leucine-rich repeat 204..227 CDD:275380 7/22 (32%)
LRR 8 227..248 4/20 (20%)
leucine-rich repeat 228..251 CDD:275380 5/22 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 346..446 4/11 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.