Protein Alignment kek2 and LOC563710

DIOPT Version :10

• Sequence 1: NP_523551.1
• Gene: kek2 / 34582
• FlyBaseID: FBgn0015400
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_692159.4
• Gene: LOC563710 / 563710
• -ID: -
• Length: 635
• Species: Danio rerio
• Alignment Length: 699
• Identity: 140/699 - (20%)
• Similarity: 224/699 - (32%)
• Gaps: 249/699 - (35%)

  Fly     7 W--IPLLALLAITAACP-------PEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFSGN 62
            |  :||| :.|..:|.|       |..|.|..|    .|.|......::|:.:..|.|.|:...|
Zfish     9 WFMVPLL-MQAWLSATPCFGERPCPRSCRCDGK----IVYCESSAFRDVPKNLSGGCQGLSLRYN 68

  Fly    63 ALQVLQSERFLRMDLL----------------------NLQKIYLSRNQLIRIHEKAFRGLTNLV 105
            :|..|::.:|:.::.|                      .|:::.||.|::..:|...|..:.||.
Zfish    69 SLASLKAGQFVGLNQLIWLYLDHNYIANVDARAFQGIRRLKELILSSNKITLLHNTTFHLVPNLR 133

  Fly   106 ELDLS------------------------ENALQNVPSETFQDYSSLMRLSLSGNPIRELKTSA- 145
            .||||                        .|:|:|:||..|||..:|..|.|..|.:|.:..::
Zfish   134 NLDLSYNKLQALQPGQFQGLRKLLSLHMRSNSLKNLPSRLFQDCRNLEFLDLGYNRLRSITRNSM 198

  Fly   146 ---------------FRHLSF--------------------------------LTTLELSNCQVE 163
                           |..::|                                |..|:||...::
Zfish   199 SGLLKLTELHIEHNQFSKINFFNFPRFYNLRALYLQWNRIRTMSEGLTWMWTSLQKLDLSGNDLQ 263

  Fly   164 RIENEAFVGMDNLEWLRLDGNR-IGFIQGTHILPKSLHGISLHSNRWNCDCRLLDIHFWLVNYNT 227
            .|:.|.:..|.||:.|.||.|: :...|.......||..|||..|.|:|...:..:..|:..:..
Zfish   264 EIDAEVYRAMPNLQTLNLDSNKLVNVSQEAVDAWTSLTAISLAGNMWDCGPVVCPLVAWMRTFRG 328

  Fly   228 PLAEEPKCMEPARLKGQ-VIKSLQREQLACLPEVSPQSSYTEVSEGRNMSITCLVRAIPEPKVLW 291
            .......|..|..::|: |:.::....:..:...:|.:.:...:.....|.|.....:|..|
Zfish   329 NKEINMICASPKEVQGEKVLDAVDANGVCRIAPATPSTIFVPSTPFVAFSQTPASSLVPTLK--- 390

  Fly   292 LFNGQVMSNDSLMDNLHMYYYIDETIGVSGAEEKRSEIFIYNVGAEDNGTFSCVGQNIAGTTFSN 356
                   |.||  ..:|                                     |.::.|:|.|
Zfish   391 -------SGDS--RRVH-------------------------------------GTSLEGSTSS- 408

  Fly   357 YTLRVIIKEPPV-VNEVSFPRDYMNYIVASSAGGGIIFVVLLCTIVVKCKKTSEPAKQ------- 413
                 :..:|.| ..|..|.....:.|||.|....:...::|..|.|..|:.....||
Zfish   409 -----VPSQPDVPPQEQDFEPVSFHKIVAGSVALFLSVAMILLVIYVSWKRYPSSVKQLQENSAA 468

  Fly   414 ----RKK----------------CDQVTSIAGGTD---SSTGSTQDTGMGMMKC------ASI-- 447
                |||                .|...:...|||   :.||....|..|..:|      :::
Zfish   469 ARKRRKKSRETERTLSTPLQEYYVDYKPNNTEGTDVLVNGTGPCTYTISGSRECEVPHQMSTLTF 533

  Fly   448 ------------------LNDGGDSMNGNPGLLLG-DTLTPTKAANGAAGGGIILGNQMKQNLLL 493
                              ||   .|..|.|..|.| :.|.|.:.:.             .|.:.|
Zfish   534 YRYEQPIVDYCQAHQPLRLN---MSYEGPPQSLEGLEELPPRERST-------------IQTVAL 582

  Fly   494 YATPNSAQQQLQLNVNLMGTGPGSPPLLLSNGHGLAAAYCSPPASLRNY 542
            .|.|         .:|...|||.|||...:...|.:..|.:...|: ||
Zfish   583 PAVP---------TINTGTTGPCSPPSQRAPMEGPSIPYPTTERSI-NY 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek2	NP_523551.1	LRR	<34..>204	CDD:443914	55/264 (21%)
		leucine-rich repeat	34..52	CDD:275380	3/17 (18%)
		leucine-rich repeat	54..79	CDD:275380	7/46 (15%)
		leucine-rich repeat	80..103	CDD:275380	6/22 (27%)
		leucine-rich repeat	104..127	CDD:275380	13/46 (28%)
		leucine-rich repeat	128..151	CDD:275380	6/38 (16%)
		leucine-rich repeat	152..175	CDD:275380	7/22 (32%)
		leucine-rich repeat	176..198	CDD:275380	6/22 (27%)
		LRRCT	207..256	CDD:214507	8/49 (16%)
		Ig_3	258..348	CDD:464046	10/89 (11%)
LOC563710	XP_692159.4	leucine-rich repeat	60..83	CDD:275380	6/22 (27%)
		LRR	63..>308	CDD:443914	52/244 (21%)
		leucine-rich repeat	84..107	CDD:275380	1/22 (5%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		leucine-rich repeat	132..155	CDD:275380	5/22 (23%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..203	CDD:275380	5/22 (23%)
		leucine-rich repeat	204..227	CDD:275380	2/22 (9%)
		leucine-rich repeat	228..251	CDD:275380	0/22 (0%)
		leucine-rich repeat	252..275	CDD:275380	7/22 (32%)