DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek2 and Lrrc17

DIOPT Version :9

Sequence 1:NP_523551.1 Gene:kek2 / 34582 FlyBaseID:FBgn0015400 Length:894 Species:Drosophila melanogaster
Sequence 2:NP_001020326.1 Gene:Lrrc17 / 502715 RGDID:1560165 Length:446 Species:Rattus norvegicus


Alignment Length:245 Identity:63/245 - (25%)
Similarity:101/245 - (41%) Gaps:54/245 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    93 IHEKAFRGLTNLVELDLSENALQNVPSETFQDYSSLMRLSLSGNPIRELKTSAFRHLSFLTTLEL 157
            :|||         .||..|..|..|..:..||   |:.:.|:.|.||.||.:.|.....|.:|:|
  Rat    65 LHEK---------YLDCQERKLVYVLPDWPQD---LLHMLLARNKIRVLKNNMFSKFKRLKSLDL 117

  Fly   158 SNCQVERIENEAFVGMDNLEWLRLDGNRIGFI-QGTHILPKSLHGISLHSNRWNCDCRLLDIHFW 221
            ...::.:||:|||.|::.|..|.|..|:|..: :...|....|..:.|:.|.|:|.|.|..:...
  Rat   118 QQNEISKIESEAFFGLNKLTTLLLQHNQIKVLTEEVFIYTPLLSYLRLYDNPWHCACELETLVSM 182

  Fly   222 L-VNYNTPLAEEPKCMEPARLKGQVIKSL---------QREQLACLPEVSPQSSYTEVSEGRNMS 276
            | :..|..|....||..|..|:.:.:..|         ::|:|..:|:||              .
  Rat   183 LQIPRNRNLGNYAKCGSPPALRNKKLLQLKPQELCDEEEKERLDPIPQVS--------------G 233

  Fly   277 ITCLVRAIPEPKVLWLFNGQVMSNDSLMDNLHMYYYIDETIGVSGAEEKR 326
            :..::|  ||.             ||.:  .|.|.:..:|:.....|.|:
  Rat   234 VPAVIR--PEA-------------DSTL--CHNYVFPIQTLDCKRKELKK 266

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek2NP_523551.1 leucine-rich repeat 34..52 CDD:275380
leucine-rich repeat 54..79 CDD:275380
LRR_8 79..138 CDD:290566 13/44 (30%)
LRR_RI <80..187 CDD:238064 31/93 (33%)
leucine-rich repeat 80..103 CDD:275380 3/9 (33%)
leucine-rich repeat 104..127 CDD:275380 7/22 (32%)
LRR_8 126..186 CDD:290566 21/59 (36%)
leucine-rich repeat 128..151 CDD:275380 8/22 (36%)
leucine-rich repeat 152..175 CDD:275380 9/22 (41%)
leucine-rich repeat 176..198 CDD:275380 6/22 (27%)
TPKR_C2 207..256 CDD:301599 15/58 (26%)
I-set 258..361 CDD:254352 13/69 (19%)
Ig_2 263..361 CDD:290606 10/64 (16%)
Lrrc17NP_001020326.1 leucine-rich repeat 68..86 CDD:275380 6/26 (23%)
LRR_8 89..146 CDD:290566 20/56 (36%)
leucine-rich repeat 89..111 CDD:275380 7/21 (33%)
LRR_4 110..151 CDD:289563 14/40 (35%)
leucine-rich repeat 112..135 CDD:275380 9/22 (41%)
leucine-rich repeat 136..159 CDD:275380 6/22 (27%)
leucine-rich repeat 160..210 CDD:275380 14/49 (29%)
TPKR_C2 168..>204 CDD:301599 11/35 (31%)
leucine-rich repeat 211..274 CDD:275380 16/87 (18%)
LRR_8 273..333 CDD:290566
LRR_4 273..314 CDD:289563
leucine-rich repeat 275..298 CDD:275380
LRR_4 299..337 CDD:289563
leucine-rich repeat 299..322 CDD:275380
leucine-rich repeat 323..346 CDD:275380
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.