Protein Alignment kek2 and pxdn

DIOPT Version :10

• Sequence 1: NP_523551.1
• Gene: kek2 / 34582
• FlyBaseID: FBgn0015400
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001076815.1
• Gene: pxdn / 493201
• XenbaseID: XB-GENE-923300
• Length: 1460
• Species: Xenopus tropicalis
• Alignment Length: 432
• Identity: 113/432 - (26%)
• Similarity: 187/432 - (43%)
• Gaps: 95/432 - (21%)

  Fly     1 MSGLPIWIPLLALLAITA------ACPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNF 59
            |:|...|:.|.|.|.:.|      :||.. |:|    .:.||.|....|.::| .:.|.|.:|:.
 Frog     4 MAGAGSWLYLTAGLLVVALPQLSHSCPSR-CLC----FRTTVRCMHLMLESVP-AVPPHTTILDL 62

  Fly    60 SGNALQVLQSERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENALQNVPSETFQD 124
            ..|.::.:|:                          .||:.|.||..|.|:.|.::.:|||.|:|
 Frog    63 RFNRIKDIQT--------------------------GAFKHLKNLNTLLLNNNQIKRIPSEAFKD 101

  Fly   125 YSSLMRLSLSGNPIRELKTSAFRHLSFLTTLELSNCQVERIENEAFVGMDNLEWLRLDGNRIGFI 189
            ..:|..|.|..|.|:.:...||:.|:.|..|.|...|:|.:|.|:|..:..||.|.|..|||
 Frog   102 LENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRI--- 163

  Fly   190 QGTHILP------KSLHGISLHSNRWNCDCRLLDIHFWLVNYNTPLAEE------PKCMEPARLK 242
              ||::|      :|:..:.|.||..:|||.:|    ||.:.....:|.      ..|..|.||:
 Frog   164 --THLVPGTFSQLESMKRLRLDSNALHCDCEIL----WLADLLKIYSESGNAQAAATCEYPRRLQ 222

  Fly   243 GQVIKSLQREQLAC-LPEVSPQSSYTEVSEGRNMSITCLVRAIPEPKVLWLFNGQVMS--NDSLM 304
            |:.:.::...:|.| .|.::.:....:|:.|..:..||.....|:|:::||.|...:|  :||.:
 Frog   223 GRSVSTITPSELNCERPRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRL 287

  Fly   305 DNLHMYYYIDETIGVSGAEEKRSEIFIYNVGAEDNGTFSCVGQNIAGTTFSN-YTLRVIIKEPPV 368
            :.|:     |.|            :.|.|....|.|.:.|:.:|:||...:: .||| ....|..
 Frog   288 NLLN-----DGT------------LMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLR-YYGTPAT 334

  Fly   369 VNEVSFPRDYMNYIVASSAGGGIIFVVLLCTIVVKCKKTSEP 410
            ...|..|:: ...:|..|             :.::|..|.:|
 Frog   335 PTFVIQPQN-TEVLVGES-------------VTLECSATGQP 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek2	NP_523551.1	LRR	<34..>204	CDD:443914	50/175 (29%)
		leucine-rich repeat	34..52	CDD:275380	5/17 (29%)
		leucine-rich repeat	54..79	CDD:275380	4/24 (17%)
		leucine-rich repeat	80..103	CDD:275380	3/22 (14%)
		leucine-rich repeat	104..127	CDD:275380	9/22 (41%)
		leucine-rich repeat	128..151	CDD:275380	8/22 (36%)
		leucine-rich repeat	152..175	CDD:275380	8/22 (36%)
		leucine-rich repeat	176..198	CDD:275380	10/27 (37%)
		LRRCT	207..256	CDD:214507	14/54 (26%)
		Ig_3	258..348	CDD:464046	21/91 (23%)
pxdn	NP_001076815.1	leucine-rich repeat	38..56	CDD:275380	5/18 (28%)
		leucine-rich repeat	57..80	CDD:275380	7/48 (15%)
		LRR	<90..>208	CDD:443914	42/126 (33%)
		leucine-rich repeat	105..128	CDD:275378	8/22 (36%)
		leucine-rich repeat	129..152	CDD:275378	8/22 (36%)
		leucine-rich repeat	153..176	CDD:275378	10/27 (37%)
		leucine-rich repeat	177..189	CDD:275378	3/11 (27%)
		LRRCT	185..236	CDD:214507	14/54 (26%)
		I-set	239..326	CDD:400151	24/103 (23%)
		Ig strand B	256..260	CDD:409490	0/3 (0%)
		Ig strand C	269..273	CDD:409490	0/3 (0%)
		Ig strand F	307..312	CDD:409490	1/4 (25%)
		Ig strand G	321..324	CDD:409490	0/2 (0%)
		I-set	335..422	CDD:400151	7/42 (17%)
		Ig strand B	352..356	CDD:409389	0/3 (0%)
		Ig strand C	365..369	CDD:409389
		Ig strand E	388..392	CDD:409389
		Ig strand F	402..407	CDD:409389
		Ig strand G	415..418	CDD:409389
		Ig3_Peroxidasin	439..512	CDD:143222
		Ig strand B	443..447	CDD:143222
		Ig strand C	456..460	CDD:143222
		Ig strand E	478..482	CDD:143222
		Ig strand F	492..497	CDD:143222
		Ig strand G	506..509	CDD:143222
		Ig4_Peroxidasin	535..603	CDD:143223
		Ig strand B	535..539	CDD:143223
		Ig strand C	548..552	CDD:143223
		Ig strand E	570..574	CDD:143223
		Ig strand F	584..589	CDD:143223
		Ig strand G	598..601	CDD:143223
		peroxidasin_like	856..1295	CDD:188658
		VWC	1402..1452	CDD:214564