DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek2 and lgi1a

DIOPT Version :9

Sequence 1:NP_523551.1 Gene:kek2 / 34582 FlyBaseID:FBgn0015400 Length:894 Species:Drosophila melanogaster
Sequence 2:NP_955921.2 Gene:lgi1a / 323011 ZFINID:ZDB-GENE-030131-1731 Length:537 Species:Danio rerio


Alignment Length:253 Identity:53/253 - (20%)
Similarity:94/253 - (37%) Gaps:62/253 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LLALLAI-----TAACPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFSGNALQVLQS 69
            |||.|.:     ::.||.. |.|    .|....|.  ....:|.........|:|..:....:..
Zfish    13 LLAALVLGGRRRSSRCPAP-CTC----SKDNALCA--NTGAIPRSFPQDVISLSFVKSGFTEIPK 70

  Fly    70 ERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENALQNVPSETFQDYSSLMRLSLS 134
            |.|:....|:|  :..:.|....|:|.||.||.:|..|.:..|.::::....|:...||:.|||:
Zfish    71 ESFIHTPALHL--LLFTANSFDSINEDAFLGLPHLEYLFIENNQIKSISPFAFRGLKSLIHLSLA 133

  Fly   135 GNPIRELKTSAFRHLSFLTTLELSNCQVERIENEAFVGMDNLEWLRLDGNRIGFIQGTHILPKSL 199
            .|                        .:|.:..:.|.||:                       :|
Zfish   134 YN------------------------NLETLPKDLFKGME-----------------------AL 151

  Fly   200 HGISLHSNRWNCDCRLLDIHFWLVNYNTPLAEEPKCMEPARLKGQVIKSLQREQLACL 257
            ..:.|..|.::|||:|..:..|:.:.|..: ::..|..|...:|:.|..|:.:...|:
Zfish   152 TKVDLRGNLFSCDCKLKWLVDWMFHTNATV-DQIFCNGPEGYQGKKINDLEAQTFDCI 208

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek2NP_523551.1 leucine-rich repeat 34..52 CDD:275380 2/17 (12%)
leucine-rich repeat 54..79 CDD:275380 4/24 (17%)
LRR_8 79..138 CDD:290566 18/58 (31%)
LRR_RI <80..187 CDD:238064 22/106 (21%)
leucine-rich repeat 80..103 CDD:275380 8/22 (36%)
leucine-rich repeat 104..127 CDD:275380 4/22 (18%)
LRR_8 126..186 CDD:290566 10/59 (17%)
leucine-rich repeat 128..151 CDD:275380 5/22 (23%)
leucine-rich repeat 152..175 CDD:275380 4/22 (18%)
leucine-rich repeat 176..198 CDD:275380 0/21 (0%)
TPKR_C2 207..256 CDD:301599 12/48 (25%)
I-set 258..361 CDD:254352 53/253 (21%)
Ig_2 263..361 CDD:290606
lgi1aNP_955921.2 LRR_8 57..113 CDD:290566 16/57 (28%)
LRR_4 77..120 CDD:289563 12/44 (27%)
leucine-rich repeat 79..102 CDD:275378 9/24 (38%)
LRR_8 101..161 CDD:290566 17/106 (16%)
LRR_4 101..141 CDD:289563 11/63 (17%)
leucine-rich repeat 103..126 CDD:275378 4/22 (18%)
leucine-rich repeat 127..150 CDD:275378 9/69 (13%)
leucine-rich repeat 151..163 CDD:275378 3/11 (27%)
TPKR_C2 159..207 CDD:301599 12/48 (25%)
EPTP 211..252 CDD:281697
EPTP 257..298 CDD:281697
EPTP 303..349 CDD:281697
EPTP 352..394 CDD:281697
EPTP 399..441 CDD:281697
EPTP 444..485 CDD:281697
EPTP 490..530 CDD:281697
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.