Protein Alignment kek2 and Lrrc4c

DIOPT Version :10

• Sequence 1: NP_523551.1
• Gene: kek2 / 34582
• FlyBaseID: FBgn0015400
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001101223.1
• Gene: Lrrc4c / 311236
• RGDID: 1311013
• Length: 640
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 129/515 - (25%)
• Similarity: 194/515 - (37%)
• Gaps: 145/515 - (28%)

  Fly     5 PIWIPLLALLAITAA-------CPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFSGN 62
            |:.:.||||..:..|       | |.||.|..:..|  |.|..:.|..:|:|:...|::||...|
  Rat    25 PLLVVLLALQLLVVAGLVRAQTC-PSVCSCSNQFSK--VICVRKNLREVPDGISTNTRLLNLHEN 86

  Fly    63 ALQVLQSERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENALQNVPSETFQDYSS 127
            .:|:::...|  ..|.:|:.:.||||.:..|...||.||.||..|:|.:|.|..:|:..|...|.
  Rat    87 QIQIIKVNSF--KHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSK 149

  Fly   128 LMRLSLSGNPIRELKTSAFRHLSFLTTLELSNC-QVERIENEAFVGMDNLEWLR----------- 180
            |..|.|..|||..:.:.||..:..|..|:|... ::..|...||.|:.||.:|.
  Rat   150 LKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPN 214

  Fly   181 -----------LDGN-----RIGFIQGTHILPK-------------------------------- 197
                       |.||     |.|..||...|.|
  Rat   215 LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNL 279

  Fly   198 ------------SLHGISLHSNRWNCDCRLLDIHFWLVNY---NTPLAEEPKCMEPARLKGQVIK 247
                        .|..|.||.|.|||:|.:|.:.:|:.:.   ||...  .:|..|..|||:.|.
  Rat   280 TLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIRDMAPSNTACC--ARCNTPPNLKGRYIG 342

  Fly   248 SLQREQLAC-LPEVSPQSSYTEVSEGRNMSITCLVRAIPE-PKVLWLF-NGQVMSNDSLMDNLHM 309
            .|.:....| .|.:....:...|:||....:.|  ||... ..|.|:. ||.||::.:.  .:.:
  Rat   343 ELDQNYFTCYAPVIVEPPADLNVTEGMAAELKC--RASTSLTSVSWITPNGTVMTHGAY--KVRI 403

  Fly   310 YYYIDETIGVSGAEEKRSEIFIYNVGAEDNGTFSCVGQNIAGTTFSNYTLRVIIKEPPVVNEVSF 374
            ....|.|:..:            ||..:|.|.::|:..|..|.|.::.||.       |....:.
  Rat   404 AVLSDGTLNFT------------NVTVQDTGMYTCMVSNSVGNTTASATLN-------VTAATTT 449

  Fly   375 PRDYMNYIVASSAGGGIIFVVLLCTIVVKCKKTSEPAKQRKKCDQVTSIAGGTDSSTGST 434
            |..|.:                  |:.|   :|.||::..         |..||::.|.|
  Rat   450 PFSYFS------------------TVTV---ETMEPSQDE---------ARTTDNNVGPT 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek2	NP_523551.1	LRR	<34..>204	CDD:443914	60/241 (25%)
		leucine-rich repeat	34..52	CDD:275380	5/17 (29%)
		leucine-rich repeat	54..79	CDD:275380	7/24 (29%)
		leucine-rich repeat	80..103	CDD:275380	10/22 (45%)
		leucine-rich repeat	104..127	CDD:275380	7/22 (32%)
		leucine-rich repeat	128..151	CDD:275380	8/22 (36%)
		leucine-rich repeat	152..175	CDD:275380	7/23 (30%)
		leucine-rich repeat	176..198	CDD:275380	11/92 (12%)
		LRRCT	207..256	CDD:214507	16/51 (31%)
		Ig_3	258..348	CDD:464046	20/91 (22%)
Lrrc4c	NP_001101223.1	LRRNT	47..80	CDD:214470	12/35 (34%)
		LRR	<76..325	CDD:443914	65/250 (26%)
		leucine-rich repeat	78..101	CDD:275380	7/24 (29%)
		leucine-rich repeat	102..125	CDD:275380	10/22 (45%)
		leucine-rich repeat	126..149	CDD:275380	7/22 (32%)
		leucine-rich repeat	150..173	CDD:275380	8/22 (36%)
		leucine-rich repeat	174..198	CDD:275380	7/23 (30%)
		leucine-rich repeat	199..220	CDD:275380	2/20 (10%)
		leucine-rich repeat	221..244	CDD:275380	7/22 (32%)
		leucine-rich repeat	245..268	CDD:275380	2/22 (9%)
		leucine-rich repeat	269..290	CDD:275380	0/20 (0%)
		IG_like	360..443	CDD:214653	24/105 (23%)
		Ig strand B	371..375	CDD:409390	0/3 (0%)
		Ig strand C	383..387	CDD:409390	1/3 (33%)
		Ig strand E	409..413	CDD:409390	1/3 (33%)
		Ig strand F	423..428	CDD:409390	1/4 (25%)
		Ig strand G	436..439	CDD:409390	0/2 (0%)