DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek2 and Rtn4rl2

DIOPT Version :9

Sequence 1:NP_523551.1 Gene:kek2 / 34582 FlyBaseID:FBgn0015400 Length:894 Species:Drosophila melanogaster
Sequence 2:XP_006499655.1 Gene:Rtn4rl2 / 269295 MGIID:2669796 Length:480 Species:Mus musculus


Alignment Length:302 Identity:84/302 - (27%)
Similarity:126/302 - (41%) Gaps:52/302 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 IPLLALLAITAACPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVL--------------- 57
            :.||||.::|.:| |.:|.|  .....||.|.....|::|..:.|.||.|               
Mouse    79 LTLLALPSVTPSC-PMLCTC--YSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRSLRPGTF 140

  Fly    58 --------NFSGNA----------LQVLQ-----SERFLR-------MDLLNLQKIYLSRNQLIR 92
                    .||.|.          ||.|:     ..|.||       ..|..||.::|.|.||..
Mouse   141 GPNLLTLWLFSNNLSTIHPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSS 205

  Fly    93 IHEKAFRGLTNLVELDLSENALQNVPSETFQDYSSLMRLSLSGNPIRELKTSAFRHLSFLTTLEL 157
            :....||||.:|..|.|.||:|.::..:.|.|.::|..|.|.||.:|.|....||.|..|..|.|
Mouse   206 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLL 270

  Fly   158 SNCQVERIENEAFVGMDNLEWLRLDGNRIGFIQGTHI--LPKSLHGISLHSNRWNCDCRLLDIHF 220
            ...:::.:...||.|:..|..|.|..|.:..:.|..:  || :|..:.|::|.|.||||...:..
Mouse   271 HGNRLQGVHRAAFHGLSRLTILYLFNNSLASLPGEALADLP-ALEFLRLNANPWACDCRARPLWA 334

  Fly   221 WLVNYNTPLAEEPKCMEPARLKGQVIKSLQREQLACLPEVSP 262
            |....... :.:..|..|...:|:.:::|:.......|..:|
Mouse   335 WFQRARVS-SSDVTCATPPERQGRDLRALRDSDFQACPPPTP 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek2NP_523551.1 leucine-rich repeat 34..52 CDD:275380 5/17 (29%)
leucine-rich repeat 54..79 CDD:275380 13/69 (19%)
LRR_8 79..138 CDD:290566 23/58 (40%)
LRR_RI <80..187 CDD:238064 38/106 (36%)
leucine-rich repeat 80..103 CDD:275380 10/22 (45%)
leucine-rich repeat 104..127 CDD:275380 8/22 (36%)
LRR_8 126..186 CDD:290566 20/59 (34%)
leucine-rich repeat 128..151 CDD:275380 10/22 (45%)
leucine-rich repeat 152..175 CDD:275380 6/22 (27%)
leucine-rich repeat 176..198 CDD:275380 7/23 (30%)
TPKR_C2 207..256 CDD:301599 11/48 (23%)
I-set 258..361 CDD:254352 2/5 (40%)
Ig_2 263..361 CDD:290606 84/302 (28%)
Rtn4rl2XP_006499655.1 leucine-rich repeat 122..143 CDD:275380 3/20 (15%)
LRR_8 143..203 CDD:338972 14/59 (24%)
leucine-rich repeat 144..167 CDD:275380 4/22 (18%)
leucine-rich repeat 168..192 CDD:275380 5/23 (22%)
leucine-rich repeat 193..216 CDD:275380 10/22 (45%)
LRR_8 216..275 CDD:338972 21/58 (36%)
leucine-rich repeat 217..240 CDD:275380 8/22 (36%)
leucine-rich repeat 241..264 CDD:275380 10/22 (45%)
LRR_8 264..322 CDD:338972 15/58 (26%)
leucine-rich repeat 265..288 CDD:275380 6/22 (27%)
leucine-rich repeat 289..312 CDD:275380 7/23 (30%)
LRRCT 321..371 CDD:214507 11/50 (22%)
PHA03247 349..>429 CDD:223021 5/27 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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