DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek2 and Slitrk6

DIOPT Version :9

Sequence 1:NP_523551.1 Gene:kek2 / 34582 FlyBaseID:FBgn0015400 Length:894 Species:Drosophila melanogaster
Sequence 2:NP_780708.1 Gene:Slitrk6 / 239250 MGIID:2443198 Length:840 Species:Mus musculus


Alignment Length:288 Identity:80/288 - (27%)
Similarity:131/288 - (45%) Gaps:31/288 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LLALLAITAACP-PEV-------CVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFS--GNAL 64
            |||.|::.:..| |.|       |.|:.|.|...:.|..:.::.|.:...|.::..:.|  .|.|
Mouse    12 LLACLSLQSQSPMPSVRGSCDTLCNCEEKDGIMIINCEEKGINKLSQISVPPSRPFHLSLLNNGL 76

  Fly    65 QVLQSERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENALQNVPSETFQDYSSLM 129
            .:|.:..|  ..|.|...|:|..|.:..|...||.||..|.:|.::.|:|:.:..:||....:|.
Mouse    77 TMLHTNDF--SGLTNALSIHLGFNNIADIETGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLE 139

  Fly   130 RLSLSGNPIRELKTSAFRHLSFLTTLELSNCQVERIENE--AFVGMDNLEWLRLDGNR------I 186
            .|....|.|..::.|||..|:.|..|.|::..:|.:...  .||.:.:|:   |.||:      :
Mouse   140 FLQADNNFITIIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLD---LRGNQLQTLPYV 201

  Fly   187 GFIQGTHILPKSLHGISLHSNRWNCDCRLLDIHFWLVNY-NTPLAEEPKCMEPARLKGQVIKSLQ 250
            ||::  ||  ..:..:.|..|:|.|:|.||.:..||.|. ...:..:..|..|...||.|:..|:
Mouse   202 GFLE--HI--GRILDLQLEDNKWACNCELLQLKNWLENMPPQSIIGDVICYSPPPFKGSVLSRLK 262

  Fly   251 REQLACLPEVSPQSSYTEVSEGRNMSIT 278
            :|.....|.|..:.   |...|..::||
Mouse   263 KESFCPTPPVYEEH---EDPSGSLLAIT 287

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek2NP_523551.1 leucine-rich repeat 34..52 CDD:275380 2/17 (12%)
leucine-rich repeat 54..79 CDD:275380 6/26 (23%)
LRR_8 79..138 CDD:290566 18/58 (31%)
LRR_RI <80..187 CDD:238064 32/114 (28%)
leucine-rich repeat 80..103 CDD:275380 8/22 (36%)
leucine-rich repeat 104..127 CDD:275380 6/22 (27%)
LRR_8 126..186 CDD:290566 18/67 (27%)
leucine-rich repeat 128..151 CDD:275380 8/22 (36%)
leucine-rich repeat 152..175 CDD:275380 6/24 (25%)
leucine-rich repeat 176..198 CDD:275380 8/27 (30%)
TPKR_C2 207..256 CDD:301599 16/49 (33%)
I-set 258..361 CDD:254352 6/21 (29%)
Ig_2 263..361 CDD:290606 4/16 (25%)
Slitrk6NP_780708.1 leucine-rich repeat 68..89 CDD:275380 6/22 (27%)
LRR_8 69..124 CDD:290566 18/56 (32%)
LRR 1 89..110 7/20 (35%)
leucine-rich repeat 94..113 CDD:275380 7/18 (39%)
LRR 2 113..134 6/20 (30%)
LRR_8 114..172 CDD:290566 17/57 (30%)
leucine-rich repeat 114..137 CDD:275380 6/22 (27%)
LRR 3 137..158 7/20 (35%)
leucine-rich repeat 138..161 CDD:275380 8/22 (36%)
LRR_8 161..219 CDD:290566 15/64 (23%)
LRR 4 161..182 4/20 (20%)
leucine-rich repeat 162..177 CDD:275380 4/14 (29%)
LRR 5 184..205 6/23 (26%)
leucine-rich repeat 185..260 CDD:275380 23/81 (28%)
leucine-rich repeat 210..222 CDD:275378 3/11 (27%)
TPKR_C2 218..268 CDD:301599 16/49 (33%)
leucine-rich repeat 261..411 CDD:275380 8/30 (27%)
LRR 6 363..384
leucine-rich repeat 365..387 CDD:275380
LRR_8 387..444 CDD:290566
LRR 7 387..408
LRR_4 388..426 CDD:289563
LRR_4 410..449 CDD:289563
LRR 8 411..432
leucine-rich repeat 412..435 CDD:275380
LRR_8 435..493 CDD:290566
LRR 9 435..456
leucine-rich repeat 436..459 CDD:275380
LRR 10 459..480
leucine-rich repeat 460..481 CDD:275380
LRR 11 482..503
LRRCT 516..566 CDD:214507
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 717..736
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 113 1.000 Inparanoid score I4837
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

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