Protein Alignment kek2 and iglr-3

DIOPT Version :10

• Sequence 1: NP_523551.1
• Gene: kek2 / 34582
• FlyBaseID: FBgn0015400
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001293349.1
• Gene: iglr-3 / 171771
• WormBaseID: WBGene00021353
• Length: 488
• Species: Caenorhabditis elegans
• Alignment Length: 402
• Identity: 102/402 - (25%)
• Similarity: 167/402 - (41%)
• Gaps: 55/402 - (13%)

  Fly    10 LLALLAITAACPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFSGNALQVLQSERFLR 74
            ||.|..|:.:..|:.|...|...:.:.:|....|...|: :.|....|:.|.|::..:.:   ..
 Worm     8 LLFLPIISCSNAPKTCKSFWISNRPSQDCASLTLQEPPQ-LLPNVLSLSLSNNSIFRITT---FP 68

  Fly    75 MDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENALQN--VPSETFQDYSSLMRLSLSGNP 137
            .:...||.:.|.:.||.::...|......|.|||:|.|:|..  :|    ::.:||..|:|:.|.
 Worm    69 SEYRRLQSLRLDQCQLEKLDFDALSVFEQLRELDVSRNSLSKLIIP----RNLASLRVLNLAFNA 129

  Fly   138 IRELKTSAFRHLSFLTTLELSNCQVERIENEAFVGMDNLEWLRLDGNRIGFIQGTHILPKSLHGI 202
            ...:...:  ||..|..::||:.::..:.....  ..|||.:||..||...:.....|.| |..:
 Worm   130 FTYVPDMS--HLESLRLVDLSHNRLISVRPRML--PFNLEVVRLAANRFQHLSPWPFLHK-LQEL 189

  Fly   203 SLHSNRWNCDCRLLDIHFWLVNYNTPLAEEPKCMEPARLKGQVIKSLQREQLACLPEV---SPQS 264
            .:..|...|||.|.  ||  |.:...||.....|.|.|...::.||....:..|.|.|   ||:|
 Worm   190 DVTFNDLECDCSLW--HF--VTWAEKLALFDSTMLPCRRPSELRKSPIDGKTVCGPTVVTSSPES 250

  Fly   265 SYTEVSEGRNMSITCLVRAIPEPKVLWLFNGQVMSNDSLMDNLHMYYYIDETIGVSGAEEKRSE- 328
            :...:.:...|..|.|  |.|.|::.|.|||:.:|  |.:...|:            :|..:.|
 Worm   251 AVVSLDDAHVMCCTAL--ATPSPQLYWQFNGKNIS--SGLSQKHL------------SESGKLEF 299

  Fly   329 -IFIYNVGAEDNGTFSCVGQNIAGTTFSNYTLRVIIKEPPVVNEVSFPRDYMNYIVASSAGGGII 392
             :.|..|..:|.|.:.||. ::||...|              .|....||.:..::.|:.|..|.
 Worm   300 CLEIPKVRLKDMGKYKCVA-SLAGLNSS--------------KEFHVERDKIPIVLNSAEGIMIY 349

  Fly   393 FVVLLCTIVVKC 404
            ....:||.:..|
 Worm   350 CQFTICTFIGVC 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek2	NP_523551.1	LRR	<34..>204	CDD:443914	41/171 (24%)
		leucine-rich repeat	34..52	CDD:275380	3/17 (18%)
		leucine-rich repeat	54..79	CDD:275380	3/24 (13%)
		leucine-rich repeat	80..103	CDD:275380	6/22 (27%)
		leucine-rich repeat	104..127	CDD:275380	8/24 (33%)
		leucine-rich repeat	128..151	CDD:275380	6/22 (27%)
		leucine-rich repeat	152..175	CDD:275380	3/22 (14%)
		leucine-rich repeat	176..198	CDD:275380	7/21 (33%)
		LRRCT	207..256	CDD:214507	15/48 (31%)
		Ig_3	258..348	CDD:464046	26/94 (28%)
iglr-3	NP_001293349.1	LRR	<48..>197	CDD:443914	39/160 (24%)
		leucine-rich repeat	51..73	CDD:275380	3/24 (13%)
		leucine-rich repeat	74..97	CDD:275380	6/22 (27%)
		leucine-rich repeat	98..119	CDD:275380	8/24 (33%)
		leucine-rich repeat	120..141	CDD:275380	6/22 (27%)
		leucine-rich repeat	142..163	CDD:275380	3/22 (14%)
		leucine-rich repeat	164..185	CDD:275380	7/20 (35%)
		Ig_3	243..319	CDD:464046	25/92 (27%)