Protein Alignment kek2 and kek2

DIOPT Version :10

• Sequence 1: NP_523551.1
• Gene: kek2 / 34582
• FlyBaseID: FBgn0015400
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_061512480.1
• Gene: kek2 / 1280097
• VectorBaseID: AGAMI1_010202
• Length: 877
• Species: Anopheles gambiae
• Alignment Length: 972
• Identity: 439/972 - (45%)
• Similarity: 566/972 - (58%)
• Gaps: 192/972 - (19%)

  Fly    11 LALLAITAA---------CPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFSGNALQV 66
            |.|||:|.:         ||.||||||||||||||||||:.|:.||:||||||||||||||:|.:
Mosquito    10 LVLLALTVSWSALPPATGCPAEVCVCKWKGGKQTVECGGRFLNRLPDGMDPGTQVLNFSGNSLTI 74

  Fly    67 LQSERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENALQNVPSETFQDYSSLMRL 131
            ||||||.:|:|:|||||||:||||::||::||||||||||||||:|.|..||:||||||::||||
Mosquito    75 LQSERFRKMELINLQKIYLARNQLVKIHDRAFRGLTNLVELDLSDNTLSEVPTETFQDYAALMRL 139

  Fly   132 SLSGNPIRELKTSAFRHLSFLTTLELSNCQVERIENEAFVGMDNLEWLRLDGNRIGFIQGTHILP 196
            ||||||||.|:.|||:.||:||||||||||:|.:|:|||:|||||||||||||||..|:|.|:||
Mosquito   140 SLSGNPIRALRASAFKQLSYLTTLELSNCQIELVEDEAFIGMDNLEWLRLDGNRIATIRGAHVLP 204

  Fly   197 KSLHGISLHSNRWNCDCRLLDIHFWLVNYNTPLAEEPKCMEPARLKGQVIKSLQREQLACLPEVS 261
            :|||||:|.||||:|||.|.|::.||.::|.|..||.||..||||.|:.:|:|..:.|||||.|:
Mosquito   205 ESLHGINLQSNRWHCDCHLTDVYTWLNSFNVPQREEIKCSGPARLAGETVKTLTLDDLACLPVVT 269

  Fly   262 PQSSYTEVSEGRNMSITCLVRAIPEPKVLWLFNGQVMSNDS-LMDNLHMYYYIDETIGVSGAEEK 325
            |::||.|::||||:|:.|.:.|.|||.|.|||.|||:.||| |..|||:||::||..|.     |
Mosquito   270 PETSYREIAEGRNISLDCRIVATPEPTVAWLFQGQVLLNDSFLSPNLHLYYFVDELDGA-----K 329

  Fly   326 RSEIFIYNVGAEDNGTFSCVGQNIAGTTFSNYTLRVIIKEPPVVNEVSFPRDYMNYIVASSAGGG 390
            .||:||||:.|:||||:|||.:|.||...:||||.||:||.|||.:|:|..:|...|||:||...
Mosquito   330 HSELFIYNINADDNGTYSCVAENSAGRVQTNYTLHVIVKEEPVVEQVTFSEEYFLAIVAASAATA 394

  Fly   391 IIFVVLLCTIVVKCKKTSEPAKQRKKCDQVTSIAGGTDS-----STGSTQD--TGM--GMMKCAS 446
            ::..:|.|.:..||      |:.|:        |.|:.:     :.|:|.|  .|:  |..||||
Mosquito   395 VLLALLCCIVACKC------ARARR--------ASGSGAKKPRGAKGATADGLVGVPAGQQKCAS 445

  Fly   447 ILNDGGDSMNGNPGLLLGDTLTPTKAANGAAGGGIILGNQMKQNLLLY--ATPNSAQQQLQLNVN 509
            |.:|            ||:.||..| .|||.|.|   .....|:::||  |.||...:....|:.
Mosquito   446 ITHD------------LGEPLTAGK-LNGALGLG---DGSNPQDIVLYLNANPNGLDKAALNNMT 494

  Fly   510 LMGTGPGSPPLLLSNGHGLAAAYCSPPASLRNYQEKNPDLVNDAESVKHKLK---TAVSLDGAGE 571
            .|                  |.:|||| |.|:||::||||:|||||.:||.:   .|:..| .||
Mosquito   495 AM------------------AQFCSPP-SARSYQDQNPDLINDAESGQHKARPRPDAIDSD-LGE 539

  Fly   572 YETQSDCGQYEGCYQLA-AAPHPHQGHQHPHPG------HPLM----GRFA-QAMTTLPR----- 619
            .::.......:|..::: .....||..|....|      :|.|    .||| .|::||||
Mosquito   540 KDSDEQSSVQDGGSEVSFQQQQQHQQQQQQQQGQGQGPYYPPMVLRGPRFASSALSTLPRGGTAA 604

  Fly   620 --GMQLKPAPHQVDVHLNPVCFLGQDGSFAYDYSSAHMVQQPPQQQQQQQQVQPANNFYRTLPHN 682
              |..|....||||:||:|.|||.|:| :..|.|.......||.            |:||||||.
Mosquito   605 LGGKDLSAYQHQVDIHLSPGCFLDQNG-YPVDLSLMAAPSGPPV------------NYYRTLPHK 656

  Fly   683 RLHKQQQFQAAAAAGGNVGVGGNPTLRYSLEAEFIQRGPT-VSYEKYQLPNVRFTAEGYPQQQQQ 746
            : |:||..|.....||    .|.|..||:.:||||.|..: .:|:.|...:||:|||||||
Mosquito   657 K-HQQQLQQQQQQPGG----PGKPIARYANDAEFINRTQSPAAYQMYAPTDVRYTAEGYPQ---- 712

  Fly   747 QQQQLQQQQQLQLQQQHQFPSPPEGYKSD---LAVM---------------PAPFQQWPSCLPGY 793
                         .:..||||||:|||.:   :|.|               |.|.||||:.|||:
Mosquito   713 -------------HEHGQFPSPPDGYKGEVHPVAYMSSAAAASAGFCVGPAPGPPQQWPTFLPGF 764

  Fly   794 RFAQSPTSLPAVATPPPAAVVATP--PPPT------------------SAVSTQSTATSTIPELD 838
            .    |..:|.:| |...|::|:|  |.|:                  ||:...|....| .|||
Mosquito   765 H----PQLIPIMA-PAGGALLASPMMPSPSGQQQQQQQLLSSPQTQPGSALKKCSVGAQT-SELD 823

  Fly   839 ESEASSPRLEEAAGSAAPPAGEEESSD------TAKLKQLNGPLADSPDEGYVGDGQETSDI 894
            :......|.||..        ||:..|      |.||:.|.||||||||||||||..|||||
Mosquito   824 KDVIPEQREEEEE--------EEDEQDGGGGGSTVKLRHLTGPLADSPDEGYVGDSHETSDI 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek2	NP_523551.1	LRR	<34..>204	CDD:443914	128/169 (76%)
		leucine-rich repeat	34..52	CDD:275380	12/17 (71%)
		leucine-rich repeat	54..79	CDD:275380	18/24 (75%)
		leucine-rich repeat	80..103	CDD:275380	17/22 (77%)
		leucine-rich repeat	104..127	CDD:275380	17/22 (77%)
		leucine-rich repeat	128..151	CDD:275380	17/22 (77%)
		leucine-rich repeat	152..175	CDD:275380	17/22 (77%)
		leucine-rich repeat	176..198	CDD:275380	16/21 (76%)
		LRRCT	207..256	CDD:214507	24/48 (50%)
		Ig_3	258..348	CDD:464046	50/90 (56%)
kek2	XP_061512480.1	None